OR51A2 Olfactory Receptor
| Gene Symbol | OR51A2 (View this gene in GeneCards) |
| Family | 51 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | HsOR11.3.38, ORL3371 |
| GeneBank Accessions | AB065797, NM_001004748 |
| ORDB | ORL3371 |
| Build #39 labels | OR51A2 |
| Chromosomal location | 11:4,976,005-4,976,943 (-) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR51A4 | 96.81% | 313 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | cOR51A16 | 87% | 305 |
| Chimp | CONTIG465.120-3413 | 96% | 313 |
| Mouse | MOR8-1 | 74% | 308 |
| Mouse | MOR8-3 | 72% | 306 |
| Mouse | MOR8-2 | 68% | 310 |
| Rat | NM_001001279 | 71% | 308 |
| Rat | NM_001000133 | 73% | 299 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB528769 |
Sequence information
| Nucleotide sequence |
ATGTCCATTATCAACACATCATATGTTGAAATCACCACCTTCTTCTTGGTTGGGATGCCA GGGCTAGAATATGCACACATCTGGATCTCTATCCCCATCTGCAGCATGTATCTTATTGCT ATTCTAGGAAATGGCACCATTCTTTTTATCATCAAGACAGAGCCCTCCTTGCATGGGCCC ATGTACTATTTTCTTTCCATGTTGGCTATGTCAGACTTGGGTTTGTCTTTATCATCTCTG CCCACTGTGTTAAGCATCTTCCTGTTCAATGCCCCTGAAACTTCTTCTAGTGCCTGCTTT GCCCAGGAATTCTTCATTCATGGATTCTCAGTACTGGAGTCCTCAGTCCTCCTGATCATG TCATTTGATAGATTCCTAGCCATCCACAATCCTCTGAGATACACCTCAATCCTGACAACT GTCAGAGTTGCCCAAATAGGGATAGTATTCTCCTTTAAGAGCATGCTCCTGGTTCTTCCC TTCCCTTTCACTTTAAGAAGCTTGAGATATTGCAAGAAAAACCAATTATCCCATTCCTAC TGTCTCCACCAGGATGTCATGAAGTTGGCCTGTTCTGACAACAGAATTGATGTTATCTAT GGCTTTTTTGGAGCACTCTGCCTTATGGTAGACTTTATTCTCATTGCTGTGTCTTACACC CTGATCCTCAAGACTGTACCGGGAATTGCATCCAAAAAGGAGGAGCTTAAGGCTCTCAAT ACTTGTGTTTCACACATCTGTGCAGTGATCATCTTCTACCTGCCCATCATCAACCTGGCC GTTGTCCACCGCTTTGCCGGGCATGTCTCTCCCCTCATTAATGTTCTCATGGCAAATGTT CTCCTACTTGTACCTCCGCTGATGAAACCAATTGTTTATTGTGTAAAAACTAAACAGATT AGAGTGAGAGTTGTAGCAAAATTGTGTCAATGGAAGATT |
| Conceptual translation |
MSIINTSYVEITTFFLVGMPGLEYAHIWISIPICSMYLIAILGNGTILFIIKTEPSLHGP MYYFLSMLAMSDLGLSLSSLPTVLSIFLFNAPETSSSACFAQEFFIHGFSVLESSVLLIM SFDRFLAIHNPLRYTSILTTVRVAQIGIVFSFKSMLLVLPFPFTLRSLRYCKKNQLSHSY CLHQDVMKLACSDNRIDVIYGFFGALCLMVDFILIAVSYTLILKTVPGIASKKEELKALN TCVSHICAVIIFYLPIINLAVVHRFAGHVSPLINVLMANVLLLVPPLMKPIVYCVKTKQI RVRVVAKLCQWKI Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 4,976,013 | 4,976,013 | NS | A/G | W/R | rs55827480 (DbSNP), 1000GP (CEU, CHBJPT, YRI) |
| 11 | 4,976,077 | 4,976,077 | NS | T/G | K/N | rs2570573 (DbSNP), 1000GP (CEU) |
| 11 | 4,976,081 | 4,976,081 | NS | G/A | T/M | rs2442426 (DbSNP) |
| 11 | 4,976,086 | 4,976,086 | SYN | T/C | P/P | rs2570572 (DbSNP) |
| 11 | 4,976,145 | 4,976,145 | NS | C/G | G/R | rs56066301 (DbSNP), 1000GP (CEU) |
| 11 | 4,976,153 | 4,976,153 | NS | C/A | R/L | rs61744535 (DbSNP) |
| 11 | 4,976,241 | 4,976,241 | NS | C/G | E/Q | rs2570571 (DbSNP), 1000GP (CEU, YRI) |
| 11 | 4,976,263 | 4,976,263 | SYN | A/C | P/P | rs74052692 (DbSNP) |
| 11 | 4,976,264 | 4,976,264 | NS | G/A | P/L | rs2442425 (DbSNP), 1000GP (CEU) |
| 11 | 4,976,291 | 4,976,291 | NS | A/G | F/S | rs55889636 (DbSNP) |
| 11 | 4,976,444 | 4,976,444 | NS | C/T | S/N | 1000GP (CEU) |
| 11 | 4,976,447 | 4,976,447 | NS | C/G | R/T | 1000GP (CEU) |
| 11 | 4,976,554 | 4,976,554 | SYN | G/A | N/N | rs2595986 (DbSNP), 1000GP (CEU) |
| 11 | 4,976,654 | 4,976,654 | NS | T/C | N/S | rs3986371 (DbSNP) |
| 11 | 4,976,656 | 4,976,656 | SYN | G/A | S/S | rs3986370 (DbSNP) |
| 11 | 4,976,659 | 4,976,659 | SYN | A/T | S/S | rs3986369 (DbSNP) |
| 11 | 4,976,663 | 4,976,663 | NS | G/A | T/I | rs2595985 (DbSNP), 1000GP (CEU) |
| 11 | 4,976,668 | 4,976,668 | SYN | A/C | P/P | 1000GP (YRI) |
| 11 | 4,976,671 | 4,976,671 | SYN | G/A | A/A | rs2595984 (DbSNP), 1000GP (CEU) |
| 11 | 4,976,768 | 4,976,768 | NS | C/T | G/E | 1000GP (CEU, YRI) |
| 11 | 4,976,788 | 4,976,788 | NS | A/C | N/K | rs35318834 (DbSNP) |
| 11 | 4,976,811 | 4,976,811 | NS | A/C | C/G | rs28482315 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 201 (Hasin) | |||
| 11 | 4,907,893 | 5,135,331 | CopyNumber | Variation_3835 (DGV) |
| 11 | 4,946,334 | 4,979,373 | CopyNumber | Variation_34970 (DGV) |
| 11 | 4,950,959 | 4,997,769 | CopyNumber | Variation_34971 (DGV) |
| 11 | 4,952,232 | 4,977,682 | CopyNumber | Variation_34973 (DGV) |
| 11 | 4,959,236 | 4,985,373 | CopyNumber | Variation_0413 (DGV), Variation_34974 (DGV) |
| 11 | 4,961,913 | 4,992,282 | CopyNumber | Variation_2900 (DGV) |
| 11 | 4,966,798 | 4,976,975 | CopyNumber | Variation_23184 (DGV) |
| 11 | 4,966,925 | 4,977,889 | CopyNumber | Variation_65847 (DGV) |
| 11 | 4,967,091 | 4,976,651 | CopyNumber | Variation_101113 (DGV) |
| 11 | 4,967,343 | 4,976,055 | CopyNumber | Variation_85627 (DGV) |
| 11 | 4,967,343 | 4,977,111 | CopyNumber | Variation_75525 (DGV) |
| 11 | 4,967,343 | 4,980,015 | CopyNumber | Variation_75523 (DGV), Variation_85626 (DGV) |
| 11 | 4,967,783 | 4,993,968 | CopyNumber | Variation_34975 (DGV) |
| 11 | 4,967,806 | 4,977,042 | CopyNumber | Variation_58515 (DGV) |
| 11 | 4,967,827 | 4,976,675 | CopyNumber | Variation_30538 (DGV) |
| 11 | 4,967,827 | 4,978,643 | CopyNumber | Variation_31803 (DGV) |
| 11 | 4,968,108 | 4,977,116 | CopyNumber | Variation_22813 (DGV) |
| 11 | 4,968,113 | 4,977,082 | CopyNumber | Variation_38836 (DGV) |
| 11 | 4,968,156 | 4,976,768 | CopyNumber | Variation_41249 (DGV) |
| 11 | 4,968,399 | 4,976,055 | CopyNumber | Variation_75524 (DGV), Variation_85625 (DGV) |
| 11 | 4,974,005 | 4,977,043 | Deletion, CopyNumber | #24 (Waszak) |
| 11 | 4,976,077 | 4,976,768 | InDel | Variation_10824 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| K289N | E235Q | P227L | S218F | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | K | E | P | S | 44.78 | 0.027 |
| 2 | N | E | P | F | 34.41 | 0.139 |
| 3 | K | Q | P | S | 14.06 | 0.033 |
| 4 | K | E | P | F | 4.38 | 0.077 |
| 5 | K | Q | P | F | 1.23 | 0.092 |
| 6 | N | E | P | S | 0.77 | 0.052 |
| 7 | K | Q | L | F | 0.23 | 0.092 |
| 8 | K | Q | L | S | 0.08 | 0.033 |
| 9 | N | E | L | F | 0.08 | 0.139 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR51A2.aApr07-unspliced | main_exon | 3UTR | chr11 | 4,976,002 | 4,976,005 | - |
| CDS | chr11 | 4,976,005 | 4,976,943 | - | ||