OR10K1 Olfactory Receptor
| Gene Symbol | OR10K11 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.36 (functional) |
| Aliases | OR1-6, HsOR1.4.4, ORL3001 |
| External Ids | HGNC: 14693 GeneBank: AB065641, BK004190, NM_001004473 ORDB: ORL3001 |
| Build #39 labels | OR10K1 |
| Chromosomal location | 1:158,465,562-158,466,500 (+) |
| Cluster | 1@159a |
| Synteny | CLIC#4 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10K2 | 83.77% | 308 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10K2 | 78% | 310 |
| Mouse | Or10k2 | 80% | 308 |
| Rat | Or10k2 | 78% | 308 |
| Cow | OR10K1C | 84% | 308 |
| Cow | OR10K1B | 82% | 313 |
| Cow | OR10K2 | 81% | 308 |
| Orang | OR10K1P | 95% | 303 |
| Horse | OR10K1D | 87% | 313 |
| Horse | OR10K1E | 87% | 308 |
| Chimp | OR10K2P | 84% | 267 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB529282 |
| GNF Atlas2 | gnf1h10880_at |
Sequence information
| Nucleotide sequence |
ATGGAGCAAGTCAATAAGACTGTGGTGAGAGAGTTCGTCGTCCTCGGCTTCTCATCCCTG GCCAGGCTGCAGCAGCTGCTCTTTGTTATCTTCCTGCTCCTCTACCTGTTCACTCTGGGC ACCAATGCAATCATCATTTCCACCATTGTGCTGGACAGAGCCCTTCATACTCCCATGTAC TTCTTCCTTGCCATCCTTTCTTGCTCTGAGATTTGCTATACCTTTGTCATTGTACCCAAG ATGCTGGTTGACCTGCTGTCCCAGAAGAAGACCATTTCTTTCCTGGGCTGTGCCATCCAA ATGTTTTCCTTCCTCTTCTTTGGCTCCTCTCACTCCTTCCTGCTGGCAGCCATGGGCTAT GATCGCTATATGGCCATCTGTAACCCACTGCGCTACTCAGTGCTCATGGGACATGGGGTG TGTATGGGACTAATGGCTGCTGCCTGTGCCTGTGGCTTCACTGTCTCCCTGGTCACCACC TCCCTAGTATTTCATCTGCCCTTCCACTCCTCCAACCAGCTCCATCACTTCTTCTGTGAC ATCTCCCCTGTCCTTAAACTGGCATCTCAGCACTCCGGCTTCAGTCAGCTGGTCATATTC ATGCTTGGTGTATTTGCCTTGGTCATTCCTCTGCTACTTATCCTAGTCTCCTACATCCGC ATCATCTCTGCCATTCTAAAAATCCCTTCCTCCGTTGGAAGATACAAGACCTTCTCCACC TGTGCCTCCCATCTCATTGTGGTAACTGTTCACTACAGTTGTGCCTCTTTCATCTACTTA AGGCCCAAGACTAATTACACTTCAAGCCAAGACACCCTAATATCTGTGTCATACACCATC CTTACCCCATTGTTCAATCCAATGATTTATAGTCTGAGAAATAAGGAATTCAAATCAGCC CTACGAAGAACAATCGGCCAAACTTTCTATCCTCTTAGT |
| Conceptual translation |
MEQVNKTVVREFVVLGFSSLARLQQLLFVIFLLLYLFTLGTNAIIISTIVLDRALHTPMY FFLAILSCSEICYTFVIVPKMLVDLLSQKKTISFLGCAIQMFSFLFFGSSHSFLLAAMGY DRYMAICNPLRYSVLMGHGVCMGLMAAACACGFTVSLVTTSLVFHLPFHSSNQLHHFFCD ISPVLKLASQHSGFSQLVIFMLGVFALVIPLLLILVSYIRIISAILKIPSSVGRYKTFST CASHLIVVTVHYSCASFIYLRPKTNYTSSQDTLISVSYTILTPLFNPMIYSLRNKEFKSA LRRTIGQTFYPLS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | C/T | T/I | 1000GP (YRI) |
| 1 | 100 | -100 | SYN | G/C | V/V | 1000GP (YRI, YRI, YRI) |
| 1 | 158,435,501 | 158,435,501 | SYN | C/G | V/V | rs6691971 (DbSNP) |
| 1 | 158,435,927 | 158,435,927 | SYN | A/C | S/S | rs16840204 (DbSNP) |
| 1 | 158,435,928 | 158,435,928 | NS | A/G | S/G | rs41273489 (DbSNP) |
| 1 | 158,466,137 | 158,466,137 | SYN | C/A | S/S | 1000GP (CHBJPT) |
| 1 | 158,466,138 | 158,466,138 | NS | G/A | G/S | 1000GP (CEU) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T74I | S103P | N172S | G193S | I221M | Y310C | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | T | S | N | G | I | Y | 91.32 | 0.501 |
| 2 | T | S | N | S | I | Y | 4.76 | 0.501 |
| 3 | I | S | N | G | I | Y | 3.15 | 0.501 |
| 4 | T | P | N | G | I | Y | 0.31 | 0.501 |
| 5 | T | S | S | G | I | Y | 0.23 | 0.501 |
| 6 | I | S | N | G | I | C | 0.08 | 0.501 |
| 7 | T | S | N | G | M | Y | 0.08 | 0.501 |
| 8 | I | P | N | G | I | Y | 0.08 | 0.501 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10K1.aApr07-unspliced | main_exon | CDS | chr1 | 158,465,562 | 158,466,500 | + |
| 3UTR | chr1 | 158,466,500 | 158,466,503 | + | ||