OR10K2 Olfactory Receptor
| Gene Symbol | OR10K21 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.21 (functional) |
| Aliases | OR1-4, HsOR1.4.2, ORL3023 |
| External Ids | HGNC: 14826 GeneBank: BK004363, NM_001004476 ORDB: ORL3023 |
| Build #39 labels | OR10K2 |
| Chromosomal location | 1:158,419,931-158,420,866 (-) |
| Cluster | 1@159a |
| Synteny | CLIC#4 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10K1 | 83.77% | 308 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10K1 | 80% | 309 |
| Mouse | Or10k2 | 81% | 311 |
| Rat | Or10k2 | 81% | 311 |
| Cow | OR10K1 | 81% | 308 |
| Orang | OR10K1P | 83% | 312 |
| Horse | OR10K1 | 82% | 307 |
| Horse | OR10K1E | 81% | 308 |
| Horse | OR10K1D | 80% | 308 |
| Chimp | OR10K1 | 86% | 310 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h03678_at |
Sequence information
| Nucleotide sequence |
ATGGAGCGGGTCAATGAGACTGTGGTGAGAGAGGTCATCTTCCTCGGCTTCTCATCCCTG GCCAGGCTGCAGCAGCTGCTCTTTGTTATCTTCCTGCTCCTCTACCTGTTCACTCTGGGC ACCAATGCAATCATCATTTCCACCATTGTCCTGGACAGGGCCCTTCATATCCCCATGTAC TTCTTCCTTGCCATCCTCTCTTGCTCTGAGATTTGCTACACCTTCATCATTGTACCCAAG ATGCTGGTTGACCTGCTGTCCCAGAAGAAGACCATTTCTTTCCTGGGCTGTGCCATCCAA ATGTTTTCCTTCCTCTTCCTTGGCTGCTCTCACTCCTTTCTGCTGGCAGTCATGGGTTAT GATCGTTACATAGCCATCTGTAACCCACTGCGCTACTCAGTGCTAATGGGACATGGGGTG TGTATGGGACTAGTGGCTGCTGCCTGTGCCTGTGGCTTCACTGTTGCACAGATCATCACA TCCTTGGTATTTCACCTGCCTTTTTATTCCTCCAATCAACTACATCACTTCTTCTGTGAC ATTGCTCCTGTCCTCAAGCTGGCATCTCACCATAACCACTTTAGTCAGATTGTCATCTTC ATGCTCTGTACATTGGTCCTGGCTATCCCCTTATTGTTGATCTTGGTGTCCTATGTTCAC ATCCTCTCTGCCATACTTCAGTTTCCTTCCACACTGGGTAGGTGCAAAGCTTTTTCTACC TGTGTATCTCACCTCATTATTGTCACTGTCCACTATGGCTGTGCCTCCTTTATCTACTTA AGGCCTCAGTCCAACTACTCCTCAAGCCAGGATGCTCTAATATCAGTATCCTACACTATT ATAACTCCATTGTTCAACCCAATGATTTATAGCTTGAGAAATAAAGAGTTCAAATCAGCT CTTTGTAAAATTGTGAGAAGAACAATTTCCCTGTTG |
| Conceptual translation |
MERVNETVVREVIFLGFSSLARLQQLLFVIFLLLYLFTLGTNAIIISTIVLDRALHIPMY FFLAILSCSEICYTFIIVPKMLVDLLSQKKTISFLGCAIQMFSFLFLGCSHSFLLAVMGY DRYIAICNPLRYSVLMGHGVCMGLVAAACACGFTVAQIITSLVFHLPFYSSNQLHHFFCD IAPVLKLASHHNHFSQIVIFMLCTLVLAIPLLLILVSYVHILSAILQFPSTLGRCKAFST CVSHLIIVTVHYGCASFIYLRPQSNYSSSQDALISVSYTIITPLFNPMIYSLRNKEFKSA LCKIVRRTISLL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | G/A | L/F | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | A/T | I/I | 1000GP (YRI, YRI, YRI) |
| 1 | 158,390,035 | 158,390,035 | NS | C/T | A/T | rs12240099 (DbSNP) |
| 1 | 158,390,119 | 158,390,119 | NS | C/T | D/N | rs73019729 (DbSNP) |
| 1 | 158,390,229 | 158,390,229 | NS | A/C | V/G | rs73019731 (DbSNP) |
| 1 | 158,390,252 | 158,390,252 | SYN | G/T | L/L | rs12239443 (DbSNP) |
| 1 | 158,390,501 | 158,390,501 | SYN | A/G | D/D | rs34616883 (DbSNP) |
| 1 | 158,420,462 | 158,420,462 | SYN | T/G | L/L | 1000GP (CEU, CHBJPT) |
| 1 | 158,420,711 | 158,420,711 | SYN | G/A | D/D | 1000GP (CEU, CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| G253S | L222F | P210R | A208T | D180N | G143V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | G | L | P | A | D | G | 97.39 | 0.309 |
| 2 | G | L | R | T | N | V | 1.00 | 0.165 |
| 3 | S | L | P | A | D | G | 0.84 | 0.309 |
| 4 | G | F | P | A | D | G | 0.61 | 0.309 |
| 5 | G | L | R | T | N | G | 0.15 | 0.165 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10K2.aApr07-unspliced | main_exon | 3UTR | chr1 | 158,419,928 | 158,419,931 | - |
| CDS | chr1 | 158,419,931 | 158,420,866 | - | ||