OR14A16 Olfactory Receptor
| Gene Symbol | OR14A161 (View this gene in GeneCards) |
| Family | 14 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.67 (pseudogene) |
| Aliases | HsOR1.5.12 |
| External Ids | HGNC: 15022 |
| Build #39 labels | OR5AT1 |
| Chromosomal location | 1:247,814,803-247,815,729 (-) |
| Cluster | 1@248 |
| Synteny | CLIC#0 |
| Remarks | Belongs to OR14- a new family which is expanded in opossum and platypus. Was previously classified into family 5 with the symbol OR5AT1. |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR14L1P | 52.61% | 287 |
| OR14A2 | 56.25% | 304 |
| OR14J1 | 51.77% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR14J1B | 53% | 311 |
| Mouse | Or14a259 | 53% | 310 |
| Rat | Or14p1 | 51% | 307 |
| Cow | OR14J12 | 53% | 311 |
| Orang | OR14A2 | 56% | 310 |
| Horse | OR14A264P | 67% | 310 |
| Chimp | OR14A262 | 62% | 302 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB463968 |
Sequence information
| Nucleotide sequence |
ATGGCAAATCTCACAATCGTGACTGAATTTATCCTTATGGGGTTTTCTACCAATAAAAAT ATGTGCATTTTGCATTCGATTCTCTTCTTGTTGATTTATTTGTGTGCCCTGATGGGGAAT GTCCTCATTATCATGATCACAACTTTGGACCATCATCTCCACACCCCCGTGTATTTCTTC TTGAAGAATCTATCTTTCTTGGATCTCTGCCTTATTTCAGTCACGGCTCCCAAATCTATC GCCAATTCTTTGATACACAACAACTCCATTTCATTCCTTGGCTGTGTTTCCCAGGTCTTT TTGTTGCTTTCTTCAGCATCTGCAGAGCTGCTCCTCCTCACGGTGATGTCCTTTGACCGC TATACTGCTATATGTCACCCTCTGCACTATGATGTCATCATGGACAGGAGCACCTGTGTC CAAAGAGCCACTGTGTCTTGGCTGTATGGGGGTCTGATTGCTGTGATGCACACAGCTGGC ACCTTCTCCTTATCCTACTGTGGGTCCAACATGGTCCATCAGTTCTTCTGTGACATTCCC CAGTTATTAGCTATTTCTTGCTCAGAAAATTTAATAAGAGAAATTGCACTCATCCTTATT AATGTAGTTTTGGATTTCTGCTGTTTTATTGTCATCATCATTACCTATGTCCACGTCTTC TCTACAGTCAAGAAGATCCCTTCCACAGAAGGCCAGTCAAAAGCCTACTCTATTTGCCTT CCACACTTGCTGGTTGTGTTATTTCTTTCCACTGGATTCATTGCTTATCTGAAGCCAGCT TCAGAGTCTCCTTCTATTTTGGATGCTGTAATTTCTGTGTTCTACACTATGCTGCCCCCA ACCTTTAATCCCATTATATACAGTTTGAGAAACAAGGCCATAAAGGTGGCTCTGGGGATG TTGATAAAGGGAAAGCTCACCAAAAAG |
| Conceptual translation |
Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 247,978,542 | 247,978,544 | Del(3) | -/AGG | rs35979231 (DbSNP) | |
| 1 | 247,978,544 | 247,978,546 | Del(3) | -/GAG | rs60157395 (DbSNP) | |
| 1 | 247,978,544 | 247,978,546 | In-Del(3) | -/CTC | rs74163811 (DbSNP) | |
| 1 | 247,978,319 | 247,978,319 | NS | A/G | I/T | rs6695283 (DbSNP) |
| 1 | 247,978,517 | 247,978,517 | NS | A/G | V/A | rs74152818 (DbSNP) |
| 1 | 247,978,436 | 247,978,436 | NS | C/A | R/L | rs61734861 (DbSNP) |
| 1 | 247,978,135 | 247,978,135 | SYN | A/C | G/G | rs12734733 (DbSNP) |
| 1 | 247,978,339 | 247,978,339 | SYN | A/G | G/G | rs6681046 (DbSNP) |
| 1 | 247,978,996 | 247,978,996 | SYN | A/G | L/L | rs10888249 (DbSNP) |
| 1 | 247,978,924 | 247,978,924 | SYN | A/G | A/A | rs56958172 (DbSNP) |
| 1 | 247,978,768 | 247,978,768 | SYN | G/A | N/N | rs61740923 (DbSNP) |
| 1 | 247,814,833 | 247,814,833 | SNP | C/A | 1000GP (CEU) | |
| 1 | 247,815,017 | 247,815,017 | SNP | A/G | 1000GP (CEU, CHBJPT) | |
| 1 | 247,815,037 | 247,815,037 | SNP | G/A | 1000GP (CEU) | |
| 1 | 247,815,466 | 247,815,466 | SNP | G/A | 1000GP (CEU) | |
| 1 | 247,815,622 | 247,815,622 | SNP | G/A | 1000GP (CEU) | |
| 1 | 247,815,694 | 247,815,694 | SNP | A/G | 1000GP (CEU, CHBJPT) | |
| 1 | 247,815,284 | 247,815,284 | SNP | T/C | 1000GP (CHBJPT) | |
| 1 | 100 | -100 | SNP | A/G | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 247,753,334 | 248,322,316 | CopyNumber | Variation_2358 (DGV) |
| 1 | 247,714,585 | 248,277,146 | CopyNumber | Variation_3339 (DGV) |
| 1 | 247,074,430 | 248,328,835 | CopyNumber | Variation_6816 (DGV) |
| 1 | 247,753,207 | 248,376,070 | CopyNumber | Variation_8353 (DGV) |
| 1 | 247,849,473 | 248,277,638 | CopyNumber | Variation_48302 (DGV) |
| 1 | 247,849,473 | 248,285,441 | CopyNumber | Variation_48303 (DGV) |
| 1 | 247,976,105 | 247,979,131 | Deletion | #184 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I238T | L199R | V172A | Y149C | L30F | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | T | L | V | Y | L | 92.93 | 0.213 |
| 2 | T | L | A | Y | L | 3.69 | 0.213 |
| 3 | T | L | V | C | L | 1.38 | 0.213 |
| 4 | T | L | V | Y | F | 1.00 | 0.213 |
| 5 | T | R | V | Y | L | 0.69 | 0.213 |
| 6 | I | L | V | Y | L | 0.31 | 0.500 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5AT1.aApr07-unspliced | main_exon | 3UTR | chr1 | 247,814,800 | 247,814,803 | - |
| CDS | chr1 | 247,814,803 | 247,815,729 | - | ||