OR2S2 Olfactory Receptor
| Gene Symbol | OR2S21 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | S |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | OST715, OR9-3, HsOR9.1.3, ORL3240 |
| External Ids | HGNC: 8276 GeneBank: AF399601, BK004443, NM_019897 ORDB: ORL3240 |
| Build #39 labels | OR2S2 |
| Chromosomal location | 9:35,957,142-35,958,098 (-) |
| Cluster | 9@36 |
| Synteny | CLIC#17 |
| Remarks | Segregating Pseudo Gene, a nonsynonymous SNP in a highly conserved amino-acid (rs2233563) |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR13C6P | 80.88% | 319 |
| OR13C7P | 82.7% | 318 |
| OR2S1P | 79.62% | 319 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC113651 |
| GNF Atlas2 | 221409_at |
Sequence information
| Nucleotide sequence |
ATGGAAAAAGCCAATGAGACCTCCCCTGTGATGGGGTTCGTTCTCCTGAGGCTCTCTGCC CACCCAGAGCTGGAAAAGACATTCTTCGTGCTCATCCTGCTGATGTACCTCGTGATCCTG CTGGGCAATGGGGTCCTCATCCTGGTGACCATCCTTGACTCCCGCCTGCACACGCCCATG TACTTCTTCCTAGGGAACCTCTCCTTCCTGGACATCTGCTTCACTACCTCCTCAGTCCCA CTGGTCCTGGACAGCTTTTTGACTCCCCAGGAAACCATCTCCTTCTCAGCCTGTGCTGTG CAGATGGCACTCTCCTTTGCCATGGCAGGAACAGAGTGCTTGCTCCTGAGCATGATGGCA TTTGATCGCTATGTGGCCATCTGCAACCCCCTTAGGTACTCCGTGATCATGAGCAAGGCT GCCTACATGCCCATGGCTGCCAGCTCCTGGGCTATTGGTGGTGCTGCTTCCGTGGTACAC ACATCCTTGGCAATTCAGCTGCCCTTCTGTGGAGACAATGTCATCAACCACTTCACCTGT GAGATTCTGGCTGTTCTAAAGTTGGCCTGTGCTGACATTTCCATCAATGTGATCAGCATG GAGGTGACGAATGTGATCTTCCTAGGAGTCCCGGTTCTGTTCATCTCTTTCTCCTATGTC TTCATCATCACCACCATCCTGAGGATCCCCTCAGCTGAGGGGAGGAAAAAGGTCTTCTCC ACCTGCTCTGCCCACCTCACCGTGGTGATCGTCTTCTACGGGACCTTATTCTTCATGTAT GGGAAGCCTAAGTCTAAGGACTCCATGGGAGCAGACAAAGAGGATCTTTCAGACAAACTC ATCCCCCTTTTCTATGGGGTGGTGACCCCGATGCTCAACCCCATCATCTATAGCCTGAGG AACAAGGATGTGAAGGCTGCTGTGAGGAGACTGCTGAGACCAAAAGGCTTCACTCAG |
| Conceptual translation |
MEKANETSPVMGFVLLRLSAHPELEKTFFVLILLMYLVILLGNGVLILVTILDSRLHTPM YFFLGNLSFLDICFTTSSVPLVLDSFLTPQETISFSACAVQMALSFAMAGTECLLLSMMA FDRYVAICNPLRYSVIMSKAAYMPMAASSWAIGGAASVVHTSLAIQLPFCGDNVINHFTC EILAVLKLACADISINVISMEVTNVIFLGVPVLFISFSYVFIITTILRIPSAEGRKKVFS TCSAHLTVVIVFYGTLFFMYGKPKSKDSMGADKEDLSDKLIPLFYGVVTPMLNPIIYSLR NKDVKAAVRRLLRPKGFTQ Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 9 | 35,957,290 | 35,957,289 | Ins(1) | -/C | rs34582331 (DbSNP) | |
| 9 | 35,957,452 | 35,957,452 | NS | A/G | I/T | rs61738501 (DbSNP) |
| 9 | 35,957,764 | 35,957,764 | NS | G/A | T/I | rs2233561 (DbSNP) |
| 9 | 35,957,383 | 35,957,383 | NS | G/A | A/V | rs2233567 (DbSNP) |
| 9 | 35,957,236 | 35,957,236 | NS | G/A | A/V | rs2233570 (DbSNP) |
| 9 | 35,957,831 | 35,957,831 | NS | G/A | P/S | rs2233560 (DbSNP) |
| 9 | 35,957,615 | 35,957,615 | NS | T/C | T/A | rs2233565 (DbSNP) |
| 9 | 35,958,047 | 35,958,047 | NS | T/C | R/G | rs2233558 (DbSNP) |
| 9 | 35,957,317 | 35,957,317 | NS | T/C | Y/C | rs2233569 (DbSNP) |
| 9 | 35,958,008 | 35,958,008 | NS | T/C | M/V | rs2233559 (DbSNP) |
| 9 | 35,957,728 | 35,957,728 | NS | T/C | H/R | rs2233563 (DbSNP) |
| 9 | 35,957,669 | 35,957,669 | NS | T/C | M/V | rs2233564 (DbSNP) |
| 9 | 35,957,577 | 35,957,577 | SYN | G/A | N/N | rs2233566 (DbSNP) |
| 9 | 35,957,355 | 35,957,355 | SYN | G/A | T/T | rs2233568 (DbSNP) |
| 9 | 35,957,760 | 35,957,760 | SYN | T/C | E/E | rs2233562 (DbSNP) |
| 9 | 35,958,050 | 35,958,050 | NS | T/C | R/G | 1000GP (CEU, CHBJPT) |
| 9 | 35,957,455 | 35,957,455 | NS | A/G | I/T | 1000GP (CEU) |
| 9 | 35,957,358 | 35,957,358 | SYN | G/A | T/T | 1000GP (CEU, CHBJPT) |
| 9 | 35,957,672 | 35,957,672 | NS | T/C | M/V | 1000GP (CEU, CHBJPT) |
| 9 | 35,957,767 | 35,957,767 | NS | G/A | T/I | 1000GP (CHBJPT) |
| 9 | 100 | -100 | NS | A/G | V/A | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 9 | 100 | -100 | SYN | G/A | T/T | 1000GP (YRI, YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| V277A | V228A | I205T | T151A | M133V | L121R | R113H | P79S | V20M | R7G | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | V | V | I | T | M | L | R | P | V | R | 62.14 | 1.000 |
| 2 | V | V | I | T | V | L | R | P | V | G | 29.49 | 1.000 |
| 3 | V | A | I | A | M | L | R | S | V | G | 3.07 | 1.000 |
| 4 | V | V | I | T | V | L | H | P | V | G | 2.23 | 1.000 |
| 5 | A | V | I | T | M | L | R | P | V | R | 0.92 | 1.000 |
| 6 | V | V | T | T | V | L | R | P | V | G | 0.77 | 1.000 |
| 7 | V | V | I | T | M | L | R | P | V | G | 0.54 | 1.000 |
| 8 | V | V | I | T | M | L | R | P | M | R | 0.46 | 1.000 |
| 9 | V | V | I | T | M | R | R | P | V | R | 0.15 | 1.000 |
| 10 | V | V | I | T | M | L | H | P | V | R | 0.15 | 1.000 |
| 11 | V | V | I | T | M | L | R | S | V | G | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2S2.aApr07-unspliced | main_exon | 3UTR | chr9 | 35,957,108 | 35,957,142 | - |
| CDS | chr9 | 35,957,142 | 35,958,098 | - | ||
| 5UTR | chr9 | 35,958,098 | 35,958,154 | - | ||