OR2T1 Olfactory Receptor
| Gene Symbol | OR2T11 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | T |
| Pseudogene | No |
| CORP pseudogene probability score | 0.05 (functional) |
| Aliases | OR1-25, OR1-61, HsOR1.5.39, ORL253 |
| External Ids | HGNC: 8277 GeneBank: AF399613, BK004463, NM_030904, U86215 ORDB: ORL253 |
| Build #39 labels | OR2T1 |
| Chromosomal location | 1:248,406,148-248,407,101 (+) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2T27 | 71.34% | 307 |
| OR2T6 | 72.79% | 305 |
| OR2T7 | 73.93% | 280 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2T6 | 71% | 312 |
| Mouse | Or2t1 | 87% | 314 |
| Rat | Or2t1 | 87% | 314 |
| Cow | OR2T6 | 71% | 314 |
| Orang | OR2T6 | 74% | 305 |
| Horse | OR2T1B | 90% | 315 |
| Horse | OR2T1C | 89% | 314 |
| Horse | OR2T1D | 88% | 318 |
| Chimp | OR2T6 | 73% | 305 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB463961 |
| GNF Atlas2 | gnf1h10655_at |
Sequence information
| Nucleotide sequence |
ATGGAAGAGTACAACACATCCTCTACAGACTTCACTTTCATGGGGCTGTTCAACAGAAAG GAAACCTCAGGTCTTATTTTTGCCATCATCTCTATCATCTTCTTCACCGCACTGATGGCC AATGGGGTTATGATCTTCCTGATCCAAACAGATTTGCGCCTTCATACACCCATGTACTTC CTCCTCAGCCACCTTTCCTTAATTGACATGATGTATATTTCCACTATTGTGCCTAAGATG CTGGTTAATTACCTGCTGGATCAAAGGACCATTTCCTTTGTGGGGTGCACAGCTCAACAC TTCCTCTACCTTACCCTTGTGGGAGCTGAATTCTTCCTGCTGGGCCTCATGGCCTATGAC CGCTATGTGGCCATTTGCAACCCTCTGAGATACCCTGTCCTCATGAGCCGCCGGGTCTGT TGGATGATTATAGCAGGTTCCTGGTTTGGGGGCTCTTTGGATGGCTTCCTCCTAACCCCC ATCACCATGAGCTTTCCCTTCTGCAATTCCCGGGAGATTAACCACTTCTTCTGTGAGGCA CCAGCAGTCCTGAAGTTGGCATGTGCAGACACAGCCCTCTACGAGACAGTGATGTATGTG TGCTGTGTTTTGATGCTGCTGATTCCTTTCTCTGTAGTCCTTGCTTCCTATGCCCGAATC CTGACTACAGTTCAGTGCATGAGCTCAGTGGAGGGCAGGAAGAAGGCATTTGCCACTTGC TCATCCCACATGACTGTGGTGTCCTTGTTCTACGGGGCTGCCATGTACACCTACATGCTG CCACATTCTTACCACAAGCCAGCCCAGGACAAAGTCCTCTCTGTGTTTTACACCATTCTC ACACCCATGCTGAACCCCCTCATCTACAGCCTTAGAAACAAGGATGTGACTGGAGCTCTG AAGAGGGCCTTGGGGAGGTTCAAGGGTCCTCAAAGGGTGTCAGGAGGTGTCTTT |
| Conceptual translation |
MEEYNTSSTDFTFMGLFNRKETSGLIFAIISIIFFTALMANGVMIFLIQTDLRLHTPMYF LLSHLSLIDMMYISTIVPKMLVNYLLDQRTISFVGCTAQHFLYLTLVGAEFFLLGLMAYD RYVAICNPLRYPVLMSRRVCWMIIAGSWFGGSLDGFLLTPITMSFPFCNSREINHFFCEA PAVLKLACADTALYETVMYVCCVLMLLIPFSVVLASYARILTTVQCMSSVEGRKKAFATC SSHMTVVSLFYGAAMYTYMLPHSYHKPAQDKVLSVFYTILTPMLNPLIYSLRNKDVTGAL KRALGRFKGPQRVSGGVF Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 248,569,674 | 248,569,674 | NS | A/G | I/V | rs41269351 (DbSNP) |
| 1 | 248,570,218 | 248,570,218 | NS | C/G | T/S | rs61736252 (DbSNP) |
| 1 | 100 | -100 | NS | A/G | I/V | 1000GP (YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | C/T | Y/Y | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 248,500,109 | 248,865,374 | CopyNumber | Variation_3340 (DGV) |
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,522,680 | 249,158,239 | CopyNumber | Variation_8355 (DGV) |
| 1 | 248,242,528 | 248,817,382 | CopyNumber | Variation_8935 (DGV) |
| 1 | 248,566,080 | 248,571,442 | CopyNumber | Variation_34795 (DGV) |
| 1 | 248,568,385 | 248,580,311 | CopyNumber | Variation_34796 (DGV) |
| 1 | 248,570,193 | 248,573,234 | CopyNumber | Variation_34797 (DGV) |
| 1 | 248,566,656 | 248,571,144 | CopyNumber | Variation_74990 (DGV), Variation_84992 (DGV) |
| 1 | 248,562,168 | 248,571,144 | CopyNumber | Variation_74991 (DGV) |
| 1 | 248,566,656 | 248,584,112 | CopyNumber | Variation_74993 (DGV) |
| 1 | 248,567,778 | 248,571,144 | CopyNumber | Variation_84988 (DGV) |
| 1 | 248,562,168 | 248,584,112 | CopyNumber | Variation_84991 (DGV) |
| 1 | 248,570,022 | 248,584,112 | CopyNumber | Variation_84993 (DGV) |
| 1 | 248,569,349 | 248,572,402 | CopyNumber | #33 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I76V | P132L | R137H | W148* | S152C | R171W | R171Q | T257S | R312T | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | I | P | R | W | S | R | R | T | R | 92.78 | 0.118 |
| 2 | V | P | R | W | S | R | R | T | R | 2.46 | 0.118 |
| 3 | I | P | R | W | S | R | R | T | T | 1.69 | 0.118 |
| 4 | I | P | R | W | S | R | R | S | R | 0.92 | 0.118 |
| 5 | I | L | R | W | S | R | R | T | R | 0.69 | 0.118 |
| 6 | I | P | R | W | S | R | Q | T | R | 0.54 | 0.118 |
| 7 | I | L | H | W | S | R | R | T | R | 0.23 | 0.118 |
| 8 | I | P | R | W | C | R | R | T | R | 0.23 | 0.118 |
| 9 | I | P | H | W | S | R | R | T | R | 0.15 | 0.118 |
| 10 | I | P | R | * | S | R | R | T | R | 0.15 | 1.200 |
| 11 | I | P | R | W | S | W | R | T | R | 0.15 | 0.118 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2T1.aApr07-unspliced | main_exon | 5UTR | chr1 | 248,405,995 | 248,406,148 | + |
| CDS | chr1 | 248,406,148 | 248,407,101 | + | ||
| 3UTR | chr1 | 248,407,101 | 248,407,104 | + | ||