OR4C16 Olfactory Receptor
Gene Symbol | OR4C161 (View this gene in GeneCards) |
Family | 4 |
Subfamily | C |
Pseudogene | No |
CORP pseudogene probability score | |
Aliases | OR11-135, HsOR11.11.16, ORL3435 |
External Ids | HGNC: 15172 GeneBank: AB065773, BK004504, NM_001004701 ORDB: ORL3435 |
Build #39 labels | OR4C16 |
Chromosomal location | 11:55,572,128-55,573,057 (+) |
Cluster | 11@56 |
Synteny | CLIC#26 |
Remarks | Segregating Pseudo Gene, a nonsynonymous SNP rs1459101 (AA change=Q/*) |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR4C11 | 67.31% | 309 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR4C137 | 77% | 310 |
Mouse | Or4c29 | 77% | 310 |
Rat | Or4c29 | 76% | 310 |
Cow | OR4C146 | 78% | 310 |
Orang | OR4A47P | 51% | 306 |
Horse | OR4C252P | 78% | 310 |
Chimp | OR4C16B | 85% | 310 |
Sequence information
Nucleotide sequence |
ATGCAACTGAATAATAATGTGACTGAGTTCATTCTGCTTGGATTGACACAGGATCCTTTT TGGAAGAAAATAGTGTTTGTTATTTTTTTGCGTCTCTACTTGGGAACACTGTTGGGTAAT TTGCTAATCATTATTAGTGTCAAGACCAGCCAGGCACTTAAGAACCCAATGTTCTTCTTC CTTTTCTACTTATCCTTATCTGATACTTGCCTCTCTACTTCCATAACCCCTAGAATGATT GTGGATGCCCTTTTGAAGAAGACAACTATCTCCTTCAGCGAGTGCATGATCCAAGTCTTT TCATCCCATGTCTTTGGCTGCCTGGAGATCTTCATCCTCATCCTCACGGCTGTTGACCGC TATGTGGACATCTGTAAGCCCCTGCACTACATGACCATCATAAGCCAGTGGGTCTGTGGT GTTTTGATGGCTGTGGCCTGGGTGGGATCCTGTGTGCATTCTTTAGTTCAGATTTTTCTT GCCCTGAGTTTGCCATTCTGTGGCCCCAATGTGATCAATCACTGTTTCTGTGACTTGCAG CCCTTGTTGAAACAAGCCTGTTCAGAAACCTATGTGGTTAACCTACTCCTGGTTTCCAAT AGTGGGGCCATTTGTGCAGTGAGTTATGTCATGCTAATATTCTCCTATGTCATCTTCTTG CATTCTCTGAGAAACCACAGTGCTGAAGTGATAAAGAAAGCACTTTCCACATGTGTCTCC CACATCATTGTGGTCATCTTGTTCTTTGGACCTTGCATATTTATGTACACATGCCTTGCA ACCGTATTCCCCATGGATAAGATGATAGCTGTATTTTATACAGTTGGAACATCTTTTCTC AACCCTGTGATTTACACGCTGAAGAATACAGAAGTGAAAAGTGCCATGAGGAAGCTTTGG AGCAAGAAATTGATCACAGATGACAAAAGA |
Conceptual translation |
MQLNNNVTEFILLGLTQDPFWKKIVFVIFLRLYLGTLLGNLLIIISVKTSQALKNPMFFF LFYLSLSDTCLSTSITPRMIVDALLKKTTISFSECMIQVFSSHVFGCLEIFILILTAVDR YVDICKPLHYMTIISQWVCGVLMAVAWVGSCVHSLVQIFLALSLPFCGPNVINHCFCDLQ PLLKQACSETYVVNLLLVSNSGAICAVSYVMLIFSYVIFLHSLRNHSAEVIKKALSTCVS HIIVVILFFGPCIFMYTCLATVFPMDKMIAVFYTVGTSFLNPVIYTLKNTEVKSAMRKLW SKKLITDDKR Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
11 | 55,339,652 | 55,339,652 | nonsense SNP | T/C | */Q | rs1459101 (DbSNP) |
11 | 55,340,170 | 55,340,170 | NS | A/C | E/D | rs61916568 (DbSNP) |
11 | 55,340,210 | 55,340,210 | NS | A/G | T/A | rs12288690 (DbSNP) |
11 | 55,340,466 | 55,340,466 | NS | A/G | K/R | rs56111016 (DbSNP) |
11 | 55,339,829 | 55,339,829 | NS | A/G | T/A | rs557590 (DbSNP) |
11 | 55,340,379 | 55,340,379 | NS | C/T | P/L | rs559449 (DbSNP) |
11 | 55,339,748 | 55,339,748 | NS | G/A | A/T | rs558465 (DbSNP) |
11 | 55,339,676 | 55,339,676 | NS | G/T | V/L | rs12800642 (DbSNP) |
11 | 55,339,702 | 55,339,702 | SYN | C/T | Y/Y | rs34100491 (DbSNP) |
11 | 55,339,798 | 55,339,798 | SYN | C/T | S/S | rs557667 (DbSNP) |
11 | 55,572,176 | 55,572,176 | nonsense SNP | C/T | Q/* | 1000GP (CEU, CHBJPT) |
11 | 55,572,353 | 55,572,353 | NS | A/G | T/A | 1000GP (CEU, CHBJPT) |
11 | 55,572,694 | 55,572,694 | NS | A/C | E/D | 1000GP (CEU) |
11 | 55,572,372 | 55,572,372 | NS | A/G | D/G | 1000GP (CEU) |
11 | 55,572,236 | 55,572,236 | SYN | C/T | L/L | 1000GP (CEU) |
11 | 55,572,200 | 55,572,200 | NS | G/T | V/L | 1000GP (CEU, CHBJPT) |
11 | 55,572,903 | 55,572,903 | NS | T/C | L/P | 1000GP (CEU, CHBJPT) |
11 | 55,572,990 | 55,572,990 | NS | A/G | K/R | 1000GP (CEU) |
11 | 55,572,322 | 55,572,322 | SYN | C/T | S/S | 1000GP (CEU) |
11 | 55,572,264 | 55,572,264 | NS | G/C | S/T | 1000GP (CEU) |
11 | 55,572,228 | 55,572,228 | NS | T/G | L/W | 1000GP (CEU) |
11 | 55,572,226 | 55,572,226 | SYN | C/T | Y/Y | 1000GP (CEU, CHBJPT) |
11 | 100 | -100 | nonsense SNP | C/T | Q/* | 1000GP (YRI) |
11 | 100 | -100 | NS | G/T | V/L | 1000GP (YRI, YRI, YRI, YRI, YRI) |
11 | 100 | -100 | SYN | C/T | Y/Y | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
Chr | Start | End | Type | Sources |
---|---|---|---|---|
11 | 55,153,930 | 55,816,828 | CopyNumber | Variation_0308 (DGV) |
11 | 55,339,702 | 55,638,112 | CopyNumber | Variation_2926 (DGV) |
11 | 55,222,420 | 55,621,884 | CopyNumber | Variation_3852 (DGV) |
11 | 54,835,623 | 55,879,426 | CopyNumber | Variation_8690 (DGV) |
11 | 55,121,706 | 55,340,753 | CopyNumber | Variation_9185 (DGV) |
11 | 55,276,602 | 55,355,722 | CopyNumber | Variation_9186 (DGV) |
11 | 55,335,878 | 55,453,486 | CopyNumber | Variation_48051 (DGV) |
11 | 55,339,829 | 55,447,427 | CopyNumber | Variation_53140 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
Q17* | V25L | L34W | S46T | K48T | T49A | T76A | D82G | V152M | E189D | A203T | V239I | L259P | K288R | % Freq | CORP | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Q | V | L | S | K | T | A | D | V | E | A | V | L | K | 36.64 | 1.000 |
2 | * | V | L | S | K | T | A | D | V | E | A | V | P | K | 27.57 | 1.200 |
3 | Q | L | L | S | K | T | A | D | V | E | A | V | P | K | 17.67 | 1.000 |
4 | Q | V | L | S | K | T | T | D | V | E | A | V | L | K | 10.37 | 1.000 |
5 | Q | V | W | T | K | T | A | D | V | D | A | V | P | R | 2.30 | 1.000 |
6 | Q | V | L | S | K | T | A | D | V | E | A | V | P | K | 2.07 | 1.000 |
7 | Q | V | L | S | K | T | T | D | V | E | T | V | L | K | 1.00 | 1.000 |
8 | Q | V | L | S | K | T | A | D | V | E | A | I | L | K | 0.54 | 1.000 |
9 | Q | V | L | S | K | A | A | D | V | E | A | V | P | K | 0.38 | 1.000 |
10 | Q | V | L | S | K | T | A | D | M | E | A | V | L | K | 0.31 | 1.000 |
11 | Q | L | L | S | K | T | A | D | V | E | A | V | L | K | 0.15 | 1.000 |
12 | Q | V | W | T | T | T | A | D | V | D | A | V | P | R | 0.15 | 1.000 |
13 | Q | V | L | S | K | T | A | G | V | E | A | V | L | K | 0.15 | 1.000 |
14 | Q | V | L | S | K | T | A | D | V | E | T | V | L | K | 0.08 | 1.000 |
15 | Q | V | L | T | K | T | T | D | V | E | A | V | L | K | 0.08 | 1.000 |
16 | * | V | L | T | K | T | A | D | V | D | A | V | P | R | 0.08 | 1.200 |
17 | Q | V | W | T | K | T | A | D | V | D | A | V | P | K | 0.08 | 1.000 |
18 | * | V | L | S | K | T | A | D | V | D | A | V | P | K | 0.08 | 1.200 |
19 | Q | V | L | T | K | T | A | D | V | D | A | V | P | K | 0.08 | 1.000 |
20 | Q | V | W | S | K | T | T | D | V | E | A | V | L | R | 0.08 | 1.000 |
21 | * | V | W | T | K | T | A | D | V | D | A | V | P | R | 0.08 | 1.200 |
22 | * | V | L | S | K | T | T | D | V | E | A | V | P | K | 0.08 | 1.200 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR4C16.aApr07-unspliced | main_exon | CDS | chr11 | 55,572,128 | 55,573,057 | + |
3UTR | chr11 | 55,573,057 | 55,573,060 | + |