OR4N5 Olfactory Receptor
| Gene Symbol | OR4N51 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | N |
| Pseudogene | No |
| CORP pseudogene probability score | 0.45 (functional) |
| Aliases | OR14-33, HsOR14.1.23, ORL3685 |
| External Ids | HGNC: 15358 GeneBank: AB065890, BK004451, NM_001004724 ORDB: ORL3685 |
| Build #39 labels | OR4N5 |
| Chromosomal location | 14:20,143,736-20,144,659 (+) |
| Cluster | 14@20b |
| Synteny | CLIC#32 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4N1P | 83.88% | 304 |
| OR4N2 | 84.64% | 306 |
| OR4N4 | 83.77% | 308 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4N2 | 85% | 305 |
| Dog | OR4N2B | 84% | 308 |
| Mouse | Or4n5 | 86% | 308 |
| Rat | Or4n5 | 87% | 308 |
| Cow | OR4N4 | 87% | 308 |
| Cow | OR4N2C | 86% | 307 |
| Cow | OR4N2 | 86% | 306 |
| Orang | OR4N1P | 83% | 308 |
| Orang | OR4N2 | 83% | 306 |
| Horse | OR4N2D | 87% | 306 |
| Horse | OR4N2E | 86% | 306 |
| Horse | OR4N2 | 86% | 305 |
| Chimp | OR4N2 | 85% | 306 |
Sequence information
| Nucleotide sequence |
ATGGAAACACAGAACCTCACAGTGGTGACAGAATTCATTCTTCTTGGTCTGACCCAGTCT CAAGATGCTCAACTTCTGGTCTTTGTGCTAGTCTTAATTTTCTACCTTATCATCCTCCCT GGAAATTTCCTCATCATTTTCACCATAAAGTCAGACCCTGGGCTCACAGCCCCCCTCTAT TTCTTTCTGGGCAACTTGGCCTTACTGGATGCATCCTACTCCTTCATTGTGGTTCCCAGG ATGTTGGTGGACTTCCTCTCTGAGAAGAAGGTAATCTCCTATAGAAGCTGCATCACTCAG CTCTTTTTCTTGCATTTTCTTGGAGCGGGAGAGATGTTCCTCCTCGTTGTGATGGCCTTT GACCGCTACATCGCCATCTGCCGGCCTTTACACTATTCAACCATCATGAACCCTAGAGCC TGCTATGCATTATCGTTGGTTCTGTGGCTTGGGGGCTTTATCCATTCCATTGTACAAGTA GCCCTTATCCTGCACTTGCCTTTCTGTGGCCCAAACCAGCTCGATAACTTCTTCTGTGAT GTTCCACAGGTCATCAAGCTGGCCTGCACCAATACCTTTGTGGTGGAGCTTCTGATGGTC TCCAACAGTGGCCTGCTCAGCCTCCTGTGCTTCCTGGGCCTTCTGGCCTCCTATGCAGTC ATCCTCTGTCGTATAAGGGAGCACTCCTCTGAAGGAAAGAGCAAGGCTATTTCCACATGC ACCACCCATATTATCATTATATTTCTCATGTTTGGACCTGCTATTTTCATCTACACTTGC CCCTTCCAGGCTTTCCCAGCTGACAAGGTAGTTTCTCTTTTCCATACTGTCATCTTTCCT TTGATGAACCCTGTTATTTATACGCTTCGCAACCAGGAGGTGAAAGCTTCCATGAGGAAG TTGTTAAGTCAACATATGTTTTGC |
| Conceptual translation |
METQNLTVVTEFILLGLTQSQDAQLLVFVLVLIFYLIILPGNFLIIFTIKSDPGLTAPLY FFLGNLALLDASYSFIVVPRMLVDFLSEKKVISYRSCITQLFFLHFLGAGEMFLLVVMAF DRYIAICRPLHYSTIMNPRACYALSLVLWLGGFIHSIVQVALILHLPFCGPNQLDNFFCD VPQVIKLACTNTFVVELLMVSNSGLLSLLCFLGLLASYAVILCRIREHSSEGKSKAISTC TTHIIIIFLMFGPAIFIYTCPFQAFPADKVVSLFHTVIFPLMNPVIYTLRNQEVKASMRK LLSQHMFC Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 14 | 20,612,300 | 20,612,299 | Ins(1) | -/C | rs36058896 (DbSNP) | |
| 14 | 20,612,267 | 20,612,267 | NS | A/G | T/A | rs74033809 (DbSNP) |
| 14 | 20,612,763 | 20,612,763 | NS | A/G | H/R | rs10141025 (DbSNP) |
| 14 | 20,612,465 | 20,612,465 | NS | A/G | N/D | rs10131326 (DbSNP) |
| 14 | 20,612,286 | 20,612,286 | NS | A/G | H/R | rs55660957 (DbSNP) |
| 14 | 20,612,595 | 20,612,595 | NS | C/G | T/S | rs10140908 (DbSNP) |
| 14 | 20,612,672 | 20,612,672 | NS | C/T | R/C | rs10134472 (DbSNP) |
| 14 | 20,611,974 | 20,611,974 | NS | G/T | G/V | rs11622442 (DbSNP) |
| 14 | 20,612,158 | 20,612,158 | SYN | A/G | E/E | rs28408764 (DbSNP) |
| 14 | 20,612,290 | 20,612,290 | SYN | C/T | Y/Y | rs17308206 (DbSNP) |
| 14 | 20,612,605 | 20,612,605 | SYN | C/T | I/I | rs10134379 (DbSNP) |
| 14 | 20,143,999 | 20,143,999 | SYN | G/A | E/E | 1000GP (CHBJPT) |
| 14 | 20,144,108 | 20,144,108 | NS | G/A | A/T | 1000GP (CHBJPT) |
| 14 | 20,144,131 | 20,144,131 | SYN | T/C | Y/Y | 1000GP (CHBJPT) |
| 14 | 20,144,186 | 20,144,186 | NS | G/T | G/W | 1000GP (CHBJPT) |
| 14 | 20,144,257 | 20,144,257 | SYN | C/T | L/L | 1000GP (CHBJPT) |
| 14 | 20,144,306 | 20,144,306 | NS | A/G | N/D | 1000GP (CHBJPT) |
| 14 | 20,144,436 | 20,144,436 | NS | G/C | S/T | 1000GP (CHBJPT) |
| 14 | 20,144,446 | 20,144,446 | SYN | T/C | I/I | 1000GP (CHBJPT) |
| 14 | 20,144,513 | 20,144,513 | NS | T/C | C/R | 1000GP (CHBJPT) |
| 14 | 20,144,604 | 20,144,604 | NS | G/A | R/H | 1000GP (CHBJPT) |
| 14 | 100 | -100 | SYN | G/A | E/E | 1000GP (YRI, YRI, YRI) |
| 14 | 100 | -100 | NS | G/A | A/T | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 14 | 20,203,125 | 20,626,160 | CopyNumber | Variation_8763 (DGV) |
| 14 | 20,203,125 | 20,716,841 | CopyNumber | Variation_8765 (DGV) |
| 14 | 20,203,125 | 20,655,466 | CopyNumber | Variation_34656 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| A125T | H131R | N191D | R224H | S234T | C260R | C260F | T288M | R290H | F307L | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | A | H | N | R | S | C | C | T | R | F | 95.47 | 0.551 |
| 2 | T | H | D | R | T | R | C | T | H | F | 2.00 | 1.000 |
| 3 | A | R | N | R | S | C | C | T | R | F | 1.69 | 0.551 |
| 4 | A | H | N | R | S | C | C | M | R | F | 0.38 | 0.551 |
| 5 | T | H | D | H | T | R | C | T | H | F | 0.15 | 1.000 |
| 6 | A | R | N | R | S | C | F | T | R | F | 0.15 | 0.551 |
| 7 | A | H | N | R | S | C | F | T | R | F | 0.08 | 0.551 |
| 8 | A | H | N | R | S | C | C | T | R | L | 0.08 | 0.551 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR4N5.aApr07-unspliced | main_exon | CDS | chr14 | 20,143,736 | 20,144,659 | + |
| 3UTR | chr14 | 20,144,659 | 20,144,662 | + | ||