OR51A2 Olfactory Receptor

Gene Symbol	OR51A2¹ (View this gene in GeneCards)
Family	51
Subfamily	A
Pseudogene	No
CORP pseudogene probability score
Aliases	HsOR11.3.38, ORL3371
External Ids	HGNC: 14764 GeneBank: AB065797, NM_001004748 ORDB: ORL3371
Build #39 labels	OR51A2
Chromosomal location	11:4,954,775-4,955,713 (-)
Cluster	11@5
Synteny	CLIC#23
Remarks

Most Similar ORs in Humans (Paralogs)

Symbol	Percent	Length
OR51A4	96.81%	313

Most Similar ORs in other species (Orthologs)

Specie	Symbol	Percent	Length
Dog	OR51A4	86%	313
Mouse	Or51a6	74%	308
Rat	Or51a7b	71%	308
Cow	OR51A4P	84%	313
Cow	OR51A4B	82%	313
Orang	OR51A4	95%	313
Orang	OR51A4DP	96%	227
Horse	OR51A5	71%	312
Chimp	OR51A4	96%	313

Expression evidences

Source	Accession
mRNA	AB528769

Sequence information

Nucleotide sequence

ATGTCCATTATCAACACATCATATGTTGAAATCACCACCTTCTTCTTGGTTGGGATGCCA
GGGCTAGAATATGCACACATCTGGATCTCTATCCCCATCTGCAGCATGTATCTTATTGCT
ATTCTAGGAAATGGCACCATTCTTTTTATCATCAAGACAGAGCCCTCCTTGCATGGGCCC
ATGTACTATTTTCTTTCCATGTTGGCTATGTCAGACTTGGGTTTGTCTTTATCATCTCTG
CCCACTGTGTTAAGCATCTTCCTGTTCAATGCCCCTGAAACTTCTTCTAGTGCCTGCTTT
GCCCAGGAATTCTTCATTCATGGATTCTCAGTACTGGAGTCCTCAGTCCTCCTGATCATG
TCATTTGATAGATTCCTAGCCATCCACAATCCTCTGAGATACACCTCAATCCTGACAACT
GTCAGAGTTGCCCAAATAGGGATAGTATTCTCCTTTAAGAGCATGCTCCTGGTTCTTCCC
TTCCCTTTCACTTTAAGAAGCTTGAGATATTGCAAGAAAAACCAATTATCCCATTCCTAC
TGTCTCCACCAGGATGTCATGAAGTTGGCCTGTTCTGACAACAGAATTGATGTTATCTAT
GGCTTTTTTGGAGCACTCTGCCTTATGGTAGACTTTATTCTCATTGCTGTGTCTTACACC
CTGATCCTCAAGACTGTACCGGGAATTGCATCCAAAAAGGAGGAGCTTAAGGCTCTCAAT
ACTTGTGTTTCACACATCTGTGCAGTGATCATCTTCTACCTGCCCATCATCAACCTGGCC
GTTGTCCACCGCTTTGCCGGGCATGTCTCTCCCCTCATTAATGTTCTCATGGCAAATGTT
CTCCTACTTGTACCTCCGCTGATGAAACCAATTGTTTATTGTGTAAAAACTAAACAGATT
AGAGTGAGAGTTGTAGCAAAATTGTGTCAATGGAAGATT

Conceptual translation

MSIINTSYVEITTFFLVGMPGLEYAHIWISIPICSMYLIAILGNGTILFIIKTEPSLHGP
MYYFLSMLAMSDLGLSLSSLPTVLSIFLFNAPETSSSACFAQEFFIHGFSVLESSVLLIM
SFDRFLAIHNPLRYTSILTTVRVAQIGIVFSFKSMLLVLPFPFTLRSLRYCKKNQLSHSY
CLHQDVMKLACSDNRIDVIYGFFGALCLMVDFILIAVSYTLILKTVPGIASKKEELKALN
TCVSHICAVIIFYLPIINLAVVHRFAGHVSPLINVLMANVLLLVPPLMKPIVYCVKTKQI
RVRVVAKLCQWKI

Protein domains and features

Variations - SNPs

Chr	Start	End	Type	Variation	AA Change	SNP IDs
11	4,976,811	4,976,811	NS	A/C	C/G	rs28482315 (DbSNP)
11	4,976,788	4,976,788	NS	A/C	N/K	rs35318834 (DbSNP)
11	4,976,291	4,976,291	NS	A/G	F/S	rs55889636 (DbSNP)
11	4,976,013	4,976,013	NS	A/G	W/R	rs55827480 (DbSNP)
11	4,976,153	4,976,153	NS	C/A	R/L	rs61744535 (DbSNP)
11	4,976,145	4,976,145	NS	C/G	G/R	rs56066301 (DbSNP)
11	4,976,241	4,976,241	NS	C/G	E/Q	rs2570571 (DbSNP)
11	4,976,663	4,976,663	NS	G/A	T/I	rs2595985 (DbSNP)
11	4,976,081	4,976,081	NS	G/A	T/M	rs2442426 (DbSNP)
11	4,976,264	4,976,264	NS	G/A	P/L	rs2442425 (DbSNP)
11	4,976,654	4,976,654	NS	T/C	N/S	rs3986371 (DbSNP)
11	4,976,077	4,976,077	NS	T/G	K/N	rs2570573 (DbSNP)
11	4,976,263	4,976,263	SYN	A/C	P/P	rs74052692 (DbSNP)
11	4,976,659	4,976,659	SYN	A/T	S/S	rs3986369 (DbSNP)
11	4,976,671	4,976,671	SYN	G/A	A/A	rs2595984 (DbSNP)
11	4,976,554	4,976,554	SYN	G/A	N/N	rs2595986 (DbSNP)
11	4,976,656	4,976,656	SYN	G/A	S/S	rs3986370 (DbSNP)
11	4,976,086	4,976,086	SYN	T/C	P/P	rs2570572 (DbSNP)
11	4,955,441	4,955,441	SYN	G/A	A/A	1000GP (CEU)
11	4,955,538	4,955,538	NS	C/T	G/E	1000GP (CEU)
11	4,955,433	4,955,433	NS	G/A	T/I	1000GP (CEU)
11	4,955,034	4,955,034	NS	G/A	P/L	1000GP (CEU)
11	4,954,847	4,954,847	NS	T/G	K/N	1000GP (CEU)
11	4,955,324	4,955,324	SYN	A/G	N/N	1000GP (CEU)
11	4,955,214	4,955,214	NS	C/T	S/N	1000GP (CEU)
11	4,955,011	4,955,011	NS	C/G	E/Q	1000GP (CEU)
11	4,954,915	4,954,915	NS	C/G	G/R	1000GP (CEU)
11	4,954,783	4,954,783	NS	A/G	W/R	1000GP (CEU, CHBJPT)
11	4,955,217	4,955,217	NS	C/G	R/T	1000GP (CEU)
11	100	-100	NS	A/G	W/R	1000GP (YRI, YRI, YRI)
11	100	-100	SYN	A/C	P/P	1000GP (YRI)

Variations - CNVs

Chr	Start	End	Type	Sources
11	4,959,236	4,985,373	CopyNumber	Variation_0413 (DGV), Variation_34974 (DGV)
11	4,961,913	4,992,282	CopyNumber	Variation_2900 (DGV)
11	4,907,893	5,135,331	CopyNumber	Variation_3835 (DGV)
11	4,968,108	4,977,116	CopyNumber	Variation_22813 (DGV)
11	4,966,798	4,976,975	CopyNumber	Variation_23184 (DGV)
11	4,967,827	4,976,675	CopyNumber	Variation_30538 (DGV)
11	4,967,827	4,978,643	CopyNumber	Variation_31803 (DGV)
11	4,946,334	4,979,373	CopyNumber	Variation_34970 (DGV)
11	4,950,959	4,997,769	CopyNumber	Variation_34971 (DGV)
11	4,952,232	4,977,682	CopyNumber	Variation_34973 (DGV)
11	4,967,783	4,993,968	CopyNumber	Variation_34975 (DGV)
11	4,968,113	4,977,082	CopyNumber	Variation_38836 (DGV)
11	4,968,156	4,976,768	CopyNumber	Variation_41249 (DGV)
11	4,967,806	4,977,042	CopyNumber	Variation_58515 (DGV)
11	4,966,925	4,977,889	CopyNumber	Variation_65847 (DGV)
11	4,967,343	4,980,015	CopyNumber	Variation_75523 (DGV), Variation_85626 (DGV)
11	4,968,399	4,976,055	CopyNumber	Variation_75524 (DGV), Variation_85625 (DGV)
11	4,967,343	4,977,111	CopyNumber	Variation_75525 (DGV)
11	4,967,343	4,976,055	CopyNumber	Variation_85627 (DGV)
11	4,967,091	4,976,651	CopyNumber	Variation_101113 (DGV)
11	4,976,077	4,976,768	InDel	Variation_10824 (DGV)
			CopyNumber	201 (Hasin)
11	4,974,005	4,977,043	Deletion, CopyNumber	#24 (Waszak)

Haplotypes

Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.

	K289N	E235Q	P227L	S218F	% Freq	CORP
1	K	E	P	S	44.78	0.027
2	N	E	P	F	34.41	0.139
3	K	Q	P	S	14.06	0.033
4	K	E	P	F	4.38	0.077
5	K	Q	P	F	1.23	0.092
6	N	E	P	S	0.77	0.052
7	K	Q	L	F	0.23	0.092
8	K	Q	L	S	0.08	0.033
9	N	E	L	F	0.08	0.139

AceView Gene Models

The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.

Accession	Type		Chr	Start	End	Strand
OR51A2.aApr07-unspliced	main_exon	3UTR	chr11	4,954,772	4,954,775	-
OR51A2.aApr07-unspliced	main_exon	CDS	chr11	4,954,775	4,955,713	-

HORDE

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