OR51A4 Olfactory Receptor
| Gene Symbol | OR51A41 (View this gene in GeneCards) |
| Family | 51 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | HsOR11.3.37, ORL3444 |
| External Ids | HGNC: 14795 GeneBank: AB065798, NM_001005329 ORDB: ORL3444 |
| Build #39 labels | OR51A4 |
| Chromosomal location | 11:4,946,162-4,947,100 (-) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR51A2 | 96.81% | 313 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR51A8 | 74% | 308 |
| Mouse | Or51a6 | 75% | 308 |
| Rat | Or51a7b | 73% | 308 |
| Cow | OR51A4P | 86% | 313 |
| Cow | OR51A4B | 84% | 313 |
| Orang | OR51A4DP | 97% | 228 |
| Horse | OR51A5 | 71% | 312 |
| Chimp | OR51A5 | 72% | 312 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC140757 |
Sequence information
| Nucleotide sequence |
ATGTCCATTATCAACACATCATATGTTGAAATCACCACCTTCTTCTTGGTTGGGATGCCA GGGCTAGAATATGCACACATCTGGATCTCTATCCCCATCTGCAGCATGTATCTTATTGCT ATTCTAGGAAATGGCACCATTCTTTTTATCATCAAGACAGAGCCCTCCTTGCATGAGCCC ATGTACTATTTTCTTTCCATGTTGGCTATGTCAGACTTGGGTTTGTCTTTATCATCTCTG CCCACTGTGTTAAGCATCTTCCTGTTCAATGCTCCTGAAATTTCATCCAATGCCTGCTTT GCCCAGGAATTCTTCATTCATGGATTCTCAGTACTGGAGTCCTCAGTCCTCCTGATCATG TCATTTGATAGATTCCTAGCCATCCACAACCCTCTGAGATACACCTCAATCCTGACAACT GTCAGAGTTGCCCAAATAGGGATAGTATTCTCCTTTAAGAGCATGCTCCTGGTTCTTCCC TTCCCTTTCACTTTAAGAAACTTGAGATATTGCAAGAAAAACCAATTATCCCATTCCTAC TGTCTCCACCAGGATGTCATGAAGTTGGCCTGTTCTGACAACAGAATTGATGTTATCTAT GGCTTTTTTGGAGCACTCTGCCTTATGGTAGACTTTATTCTCATTGCTGTGTCTTACACC CTGATCCTCAAGACTGTACTGGGAATTGCATCCAAAAAGGAGCAGCTTAAGGCTCTCAAT ACTTGTGTTTCACACATCTGTGCAGTGATCATCTTCTACCTGCCCATCATCAACCTGGCC GTTGTCCACCGCTTTGCCCGGCATGTCTCTCCCCTCATTAATGTTCTCATGGCAAATGTT CTCCTACTTGTACCTCCACTGACGAACCCAATTGTTTATTGTGTAAAAACTAAACAGATT AGAGTGAGAGTTGTAGCAAAATTGTGTCAACGGAAGATT |
| Conceptual translation |
MSIINTSYVEITTFFLVGMPGLEYAHIWISIPICSMYLIAILGNGTILFIIKTEPSLHEP MYYFLSMLAMSDLGLSLSSLPTVLSIFLFNAPEISSNACFAQEFFIHGFSVLESSVLLIM SFDRFLAIHNPLRYTSILTTVRVAQIGIVFSFKSMLLVLPFPFTLRNLRYCKKNQLSHSY CLHQDVMKLACSDNRIDVIYGFFGALCLMVDFILIAVSYTLILKTVLGIASKKEQLKALN TCVSHICAVIIFYLPIINLAVVHRFARHVSPLINVLMANVLLLVPPLTNPIVYCVKTKQI RVRVVAKLCQRKI Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 4,967,468 | 4,967,468 | NS | A/G | M/T | rs28698374 (DbSNP) |
| 11 | 4,967,678 | 4,967,678 | NS | A/G | F/S | rs12271991 (DbSNP) |
| 11 | 4,968,198 | 4,968,198 | NS | C/A | G/C | rs3845246 (DbSNP) |
| 11 | 4,967,532 | 4,967,532 | NS | C/G | G/R | rs2595988 (DbSNP) |
| 11 | 4,967,400 | 4,967,400 | NS | G/A | R/W | rs2436782 (DbSNP) |
| 11 | 4,968,131 | 4,968,131 | NS | G/A | T/M | rs2412466 (DbSNP) |
| 11 | 4,967,464 | 4,967,464 | NS | G/T | N/K | rs73388946 (DbSNP) |
| 11 | 4,968,117 | 4,968,117 | NS | T/C | N/D | rs2412467 (DbSNP) |
| 11 | 4,967,831 | 4,967,831 | NS | T/C | N/S | rs2595987 (DbSNP) |
| 11 | 4,967,941 | 4,967,941 | SYN | A/G | N/N | rs72860814 (DbSNP) |
| 11 | 4,967,473 | 4,967,473 | SYN | C/T | P/P | rs72639631 (DbSNP) |
| 11 | 4,946,302 | 4,946,302 | NS | G/C | R/G | 1000GP (CEU) |
| 11 | 4,946,238 | 4,946,238 | NS | G/A | T/M | 1000GP (CEU, CHBJPT) |
| 11 | 4,946,421 | 4,946,421 | NS | A/G | L/P | 1000GP (CEU) |
| 11 | 4,946,601 | 4,946,601 | NS | T/C | N/S | 1000GP (CEU) |
| 11 | 100 | -100 | NS | G/A | T/M | 1000GP (YRI, YRI) |
| 11 | 100 | -100 | SYN | C/T | L/L | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 4,959,236 | 4,985,373 | CopyNumber | Variation_0413 (DGV), Variation_34974 (DGV) |
| 11 | 4,961,913 | 4,992,282 | CopyNumber | Variation_2900 (DGV) |
| 11 | 4,907,893 | 5,135,331 | CopyNumber | Variation_3835 (DGV) |
| 11 | 4,968,108 | 4,977,116 | CopyNumber | Variation_22813 (DGV) |
| 11 | 4,966,798 | 4,976,975 | CopyNumber | Variation_23184 (DGV) |
| 11 | 4,967,827 | 4,976,675 | CopyNumber | Variation_30538 (DGV) |
| 11 | 4,967,827 | 4,978,643 | CopyNumber | Variation_31803 (DGV) |
| 11 | 4,946,334 | 4,979,373 | CopyNumber | Variation_34970 (DGV) |
| 11 | 4,950,959 | 4,997,769 | CopyNumber | Variation_34971 (DGV) |
| 11 | 4,952,232 | 4,977,682 | CopyNumber | Variation_34973 (DGV) |
| 11 | 4,967,783 | 4,993,968 | CopyNumber | Variation_34975 (DGV) |
| 11 | 4,968,113 | 4,977,082 | CopyNumber | Variation_38836 (DGV) |
| 11 | 4,968,156 | 4,976,768 | CopyNumber | Variation_41249 (DGV) |
| 11 | 4,967,806 | 4,977,042 | CopyNumber | Variation_58515 (DGV) |
| 11 | 4,966,925 | 4,977,889 | CopyNumber | Variation_65847 (DGV) |
| 11 | 4,967,343 | 4,980,015 | CopyNumber | Variation_75523 (DGV), Variation_85626 (DGV) |
| 11 | 4,967,343 | 4,977,111 | CopyNumber | Variation_75525 (DGV) |
| 11 | 4,967,343 | 4,976,055 | CopyNumber | Variation_85627 (DGV) |
| 11 | 4,967,091 | 4,976,651 | CopyNumber | Variation_101113 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T288M | L227P | S218F | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | M | L | S | 70.58 | 0.038 |
| 2 | T | L | S | 14.21 | 0.038 |
| 3 | M | P | S | 6.68 | 0.038 |
| 4 | M | L | F | 6.30 | 0.105 |
| 5 | M | P | F | 2.23 | 0.105 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR51A4.aApr07-unspliced | main_exon | 3UTR | chr11 | 4,946,159 | 4,946,162 | - |
| CDS | chr11 | 4,946,162 | 4,947,100 | - | ||