OR51A7 Olfactory Receptor
| Gene Symbol | OR51A71 (View this gene in GeneCards) |
| Family | 51 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.21 (functional) |
| Aliases | OR11-27, HsOR11.3.33, ORL3300 |
| External Ids | HGNC: 15188 GeneBank: AB065525, BK004284, NM_001004749 ORDB: ORL3300 |
| Build #39 labels | OR51A7 |
| Chromosomal location | 11:4,907,370-4,908,305 (+) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR51A2 | 70.45% | 308 |
| OR51A4 | 71.75% | 308 |
| OR51A5P | 72.73% | 308 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR51A7P | 88% | 312 |
| Mouse | Or51a7 | 86% | 312 |
| Rat | Or51a7b | 86% | 312 |
| Rat | Or51a7 | 86% | 308 |
| Cow | OR51A7CP | 84% | 312 |
| Orang | OR51A8 | 75% | 308 |
| Horse | OR51A5 | 72% | 313 |
| Chimp | OR51A8 | 75% | 308 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC137063 |
| GNF Atlas2 | gnf1h10687_at |
Sequence information
| Nucleotide sequence |
ATGTCTGTTCTCAATAACTCCGAAGTCAAGCTTTTCCTTCTGATTGGGATCCCAGGACTG GAACATGCCCACATTTGGTTCTCCATCCCCATTTGCCTCATGTACCTGCTTGCCATCATG GGCAACTGCACCATTCTCTTTATTATAAAGACAGAGCCCTCGCTTCATGAGCCCATGTAT TATTTCCTTGCCATGTTGGCTGTCTCTGACATGGGCCTGTCCCTCTCCTCCCTTCCTACC ATGTTGAGGGTCTTCTTGTTCAATGCCATGGGAATTTCACCTAATGCCTGCTTTGCTCAA GAATTCTTCATTCATGGATTCACTGTCATGGAATCCTCAGTACTTCTAATTATGTCTTTG GACCGCTTTCTTGCCATTCACAATCCCTTAAGATACAGTTCTATCCTCACTAGCAACAGG GTTGCTAAAATGGGACTTATTTTAGCCATTAGGAGCATTCTCTTAGTGATTCCATTTCCC TTCACCTTAAGGAGATTAAAATATTGTCAAAAGAATCTTCTTTCTCACTCATACTGTCTT CATCAGGATACCATGAAGCTGGCCTGCTCTGACAACAAGACCAATGTCATCTATGGCTTC TTCATTGCTCTCTGTACTATGCTGGACTTGGCACTGATTGTTTTGTCTTATGTGCTGATC TTGAAGACTATACTCAGCATTGCATCTTTGGCAGAGAGGCTTAAGGCCCTAAATACCTGT GTCTCCCACATCTGTGCTGTGCTCACCTTCTATGTGCCCATCATCACCCTGGCTGCCATG CATCACTTTGCCAAGCACAAAAGCCCTCTTGTTGTGATCCTTATTGCAGATATGTTCTTG TTGGTGCCGCCCCTTATGAACCCCATTGTGTACTGTGTAAAGACTCGACAAATCTGGGAG AAGATCTTGGGGAAGTTGCTTAATGTATGTGGGAGA |
| Conceptual translation |
MSVLNNSEVKLFLLIGIPGLEHAHIWFSIPICLMYLLAIMGNCTILFIIKTEPSLHEPMY YFLAMLAVSDMGLSLSSLPTMLRVFLFNAMGISPNACFAQEFFIHGFTVMESSVLLIMSL DRFLAIHNPLRYSSILTSNRVAKMGLILAIRSILLVIPFPFTLRRLKYCQKNLLSHSYCL HQDTMKLACSDNKTNVIYGFFIALCTMLDLALIVLSYVLILKTILSIASLAERLKALNTC VSHICAVLTFYVPIITLAAMHHFAKHKSPLVVILIADMFLLVPPLMNPIVYCVKTRQIWE KILGKLLNVCGR Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | G/A | E/K | 1000GP (YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | C/A | T/T | 1000GP (YRI, YRI, YRI, YRI) |
| 11 | 4,907,391 | 4,907,391 | NS | G/A | E/K | 1000GP (CEU, CHBJPT) |
| 11 | 4,907,611 | 4,907,611 | NS | T/C | M/T | 1000GP (CEU, CHBJPT) |
| 11 | 4,907,636 | 4,907,636 | SYN | C/T | A/A | 1000GP (CEU, CHBJPT) |
| 11 | 4,907,831 | 4,907,831 | SYN | C/G | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 4,907,866 | 4,907,866 | nonsense SNP | T/G | L/* | 1000GP (CEU) |
| 11 | 4,928,621 | 4,928,621 | NS | A/G | K/E | rs11034596 (DbSNP) |
| 11 | 4,928,787 | 4,928,786 | Ins(1) | -/C | rs35302315 (DbSNP) | |
| 11 | 4,928,841 | 4,928,841 | NS | C/T | T/M | rs7108225 (DbSNP) |
| 11 | 4,928,866 | 4,928,866 | SYN | C/T | A/A | rs7941509 (DbSNP) |
| 11 | 4,929,061 | 4,929,061 | SYN | C/G | L/L | rs10500627 (DbSNP) |
| 11 | 4,929,186 | 4,929,186 | NS | C/T | A/V | rs7108654 (DbSNP) |
| 11 | 4,929,448 | 4,929,448 | SYN | A/G | P/P | rs7119629 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 91 (Hasin) | |||
| 11 | 4,907,893 | 5,135,331 | CopyNumber | Variation_3835 (DGV) |
| 11 | 4,928,500 | 4,931,535 | CopyNumber | #120 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| E8K | M81T | V196A | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | E | M | V | 70.97 | 0.118 |
| 2 | K | M | V | 21.74 | 0.118 |
| 3 | E | T | V | 5.99 | 0.118 |
| 4 | E | M | A | 1.31 | 0.118 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR51A7.aApr07-unspliced | main_exon | CDS | chr11 | 4,907,370 | 4,908,305 | + |
| 3UTR | chr11 | 4,908,305 | 4,908,308 | + | ||