OR51B4 Olfactory Receptor
| Gene Symbol | OR51B41 (View this gene in GeneCards) |
| Family | 51 |
| Subfamily | B |
| Pseudogene | No |
| CORP pseudogene probability score | 0.57 (pseudogene) |
| Aliases | HsOR11.3.55, ORL482 |
| External Ids | HGNC: 14708 GeneBank: BC069094, NM_033179 ORDB: ORL482 |
| Build #39 labels | OR51B4 |
| Chromosomal location | 11:5,301,017-5,301,946 (-) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR51B2 | 66.01% | 306 |
| OR51B5 | 65.02% | 303 |
| OR51B6 | 67.97% | 306 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR51B4P | 79% | 301 |
| Mouse | Or51b4 | 75% | 311 |
| Rat | Or51b4b | 76% | 309 |
| Cow | OR51B20P | 65% | 298 |
| Orang | OR51B4P | 89% | 310 |
| Horse | OR51B21P | 76% | 295 |
| Chimp | OR51B6 | 67% | 312 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | BG492876 |
| mRNA | BC153815 |
Sequence information
| Nucleotide sequence |
ATGTGGTATAACAACAGTGCTGGCCCCTTCTTGCTGACTGGCTTCTTGGGCTCAGAGGCA GTTCACTACCGGATCTCTATGTCCTTCTTTGTCATCTACTTCTCCGTCCTTTTTGGAAAT GGCACTCTTCTTGTCCTCATTTGGAATGATCACAGCCTCCATGAGCCCATGTACTACTTC CTGGCTATGCTGGCAGACACGGACCTTGGGATGACATTCACTACAATGCCCACAGTCCTG GGTGTCCTGCTGCTAGACCAGAGGGAGATTGCCCATGCTGCCTGTTTCACCCAATCCTTC ATTCATTCACTGGCCATTGTAGAATCAGGTATCTTGCTTGTTTTGGCCTATGACTGTTTC ATTGCCATCCGCACACCACTGAGGTACAACTGCATTCTTACCAATTCCCGAGTGATGAAC ATAGGACTGGGGGTACTGATGAGAGGTTTTATGTCCATTTTGCCCATAATTCTTTCACTC TACTGCTACCCATATTGTGGTTCCCGTGCCCTCTTGCACACATTTTGCCTCCATCAAGAT GTCATAAAACTCGCCTGTGCTGATATCACGTTTAATCACATATATCCAATTATTCAGACT TCTTTGACTGTCTTTTTAGATGCTCTAATCATCATCTTTTCTTATATACTAATCCTCAAG ACAGTGATGGGCATTGCGTCTGGACAAGAGGAAGCTAAATCTCTCAACACTTGTGTCTCC CATATTAGCTGTGTCCTAGTATTTCACATCACTGTGATGGGACTGTCATTCATTCACAGG TTTGGGAAACATGCACCTCATGTGGTCCCCATTACCATGAGCTATGTCCATTTTCTCTTT CCTCCATTCGTGAATCCTATCATTTATAGCATCAAGACCAAGCAGATTCAAAGAAGCATT ATTCGCCTATTTTCTGGGCAGAGTAGGGCT |
| Conceptual translation |
MWYNNSAGPFLLTGFLGSEAVHYRISMSFFVIYFSVLFGNGTLLVLIWNDHSLHEPMYYF LAMLADTDLGMTFTTMPTVLGVLLLDQREIAHAACFTQSFIHSLAIVESGILLVLAYDCF IAIRTPLRYNCILTNSRVMNIGLGVLMRGFMSILPIILSLYCYPYCGSRALLHTFCLHQD VIKLACADITFNHIYPIIQTSLTVFLDALIIIFSYILILKTVMGIASGQEEAKSLNTCVS HISCVLVFHITVMGLSFIHRFGKHAPHVVPITMSYVHFLFPPFVNPIIYSIKTKQIQRSI IRLFSGQSRA Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 5,300,803 | 5,300,803 | large insertion | 31595bp insertion | rs63751663 (DbSNP) | |
| 11 | 5,247,925 | 5,247,925 | large insertion | 87536bp insertion | rs63751692 (DbSNP) | |
| 11 | 5,322,606 | 5,322,606 | NS | A/G | F/L | rs57211922 (DbSNP) |
| 11 | 5,322,737 | 5,322,737 | NS | A/G | M/T | rs10837771 (DbSNP) |
| 11 | 5,322,768 | 5,322,768 | NS | C/G | G/R | rs62000996 (DbSNP) |
| 11 | 5,323,071 | 5,323,071 | NS | C/T | V/I | rs7118113 (DbSNP) |
| 11 | 5,322,674 | 5,322,674 | NS | G/A | S/F | rs62000995 (DbSNP) |
| 11 | 5,322,660 | 5,322,660 | NS | G/T | H/N | rs74049368 (DbSNP) |
| 11 | 5,323,161 | 5,323,161 | NS | T/C | S/G | rs61739194 (DbSNP) |
| 11 | 5,322,624 | 5,322,624 | NS | T/C | T/A | rs62000994 (DbSNP) |
| 11 | 5,322,520 | 5,322,520 | SYN | A/G | L/L | rs12283334 (DbSNP) |
| 11 | 5,301,841 | 5,301,841 | NS | C/T | V/I | 1000GP (CEU, CHBJPT) |
| 11 | 5,301,290 | 5,301,290 | SYN | G/A | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 5,301,507 | 5,301,507 | NS | A/G | M/T | 1000GP (CEU, CHBJPT) |
| 11 | 5,301,269 | 5,301,269 | SYN | C/T | A/A | 1000GP (CHBJPT) |
| 11 | 5,301,546 | 5,301,546 | NS | G/A | T/I | 1000GP (CHBJPT) |
| 11 | 5,301,773 | 5,301,773 | nonsense SNP | G/C | Y/* | 1000GP (CHBJPT) |
| 11 | 100 | -100 | SYN | G/A | L/L | 1000GP (YRI) |
| 11 | 100 | -100 | NS | C/T | A/T | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| A310P | T293I | A226V | A185T | H173N | S168F | M147T | R137G | T134I | L84M | Y58* | V36I | S6G | M1T | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | A | T | A | A | H | S | T | R | T | L | Y | I | S | M | 42.09 | 0.641 |
| 2 | A | T | A | A | H | S | M | R | T | L | Y | V | S | M | 29.19 | 0.641 |
| 3 | A | T | A | A | H | S | M | R | T | L | Y | I | S | M | 21.12 | 0.641 |
| 4 | A | T | A | T | H | S | M | R | T | L | Y | V | G | M | 2.76 | 0.641 |
| 5 | A | T | A | A | H | S | M | R | I | L | Y | I | S | M | 0.92 | 0.641 |
| 6 | A | T | V | A | H | S | M | R | T | L | Y | V | S | M | 0.69 | 0.641 |
| 7 | A | T | A | T | H | S | M | G | T | L | Y | V | G | M | 0.54 | 0.641 |
| 8 | A | T | A | A | H | F | M | R | T | L | Y | V | S | M | 0.46 | 0.641 |
| 9 | P | T | A | A | H | S | T | R | T | L | Y | I | S | M | 0.38 | 0.641 |
| 10 | A | T | A | T | H | S | M | R | T | M | Y | V | G | M | 0.38 | 0.641 |
| 11 | A | T | A | A | H | S | M | R | T | L | Y | I | S | T | 0.31 | 1.200 |
| 12 | A | T | A | A | H | S | T | R | T | L | Y | V | S | M | 0.23 | 0.641 |
| 13 | A | T | A | A | H | S | T | R | I | L | Y | I | S | M | 0.23 | 0.641 |
| 14 | A | T | A | A | N | S | M | R | T | L | Y | I | S | M | 0.23 | 0.735 |
| 15 | P | T | A | A | H | S | T | R | T | L | * | I | S | M | 0.08 | 1.200 |
| 16 | A | T | A | T | H | S | M | R | T | L | Y | I | S | M | 0.08 | 0.641 |
| 17 | A | T | A | A | H | S | T | R | T | L | * | I | S | M | 0.08 | 1.200 |
| 18 | A | T | A | T | H | S | M | R | T | L | Y | V | S | M | 0.08 | 0.641 |
| 19 | A | T | A | A | H | S | M | R | T | L | Y | V | G | M | 0.08 | 0.641 |
| 20 | A | I | A | A | H | S | M | R | T | L | Y | V | S | T | 0.08 | 1.200 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR51B4.aApr07-unspliced | main_exon | 3UTR | chr11 | 5,300,139 | 5,301,017 | - |
| CDS | chr11 | 5,301,017 | 5,301,946 | - | ||