OR51I2 Olfactory Receptor
| Gene Symbol | OR51I21 (View this gene in GeneCards) |
| Family | 51 |
| Subfamily | I |
| Pseudogene | No |
| CORP pseudogene probability score | 0.12 (functional) |
| Aliases | OR11-38, HsOR11.3.66, ORL3305 |
| External Ids | HGNC: 15201 GeneBank: BK004381, NM_001004754 ORDB: ORL3305 |
| Build #39 labels | OR51I2 |
| Chromosomal location | 11:5,453,489-5,454,424 (+) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR51F5P | 56.11% | 303 |
| OR51G2 | 58.05% | 298 |
| OR51I1 | 61.67% | 300 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR51I2P | 86% | 306 |
| Mouse | Or51i2 | 89% | 312 |
| Rat | Or51i2 | 89% | 312 |
| Cow | OR51I2BP | 88% | 300 |
| Orang | OR51I1 | 62% | 301 |
| Horse | OR51I2C | 89% | 312 |
| Chimp | OR51I1 | 61% | 301 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC140730 |
| GNF Atlas2 | gnf1h05433_at |
| GNF Atlas2 | gnf1h10876_s_at |
Sequence information
| Nucleotide sequence |
ATGGGGTTGTTCAATGTCACTCACCCTGCATTCTTCCTCCTGACTGGTATCCCTGGTCTG GAGAGCTCTCACTCCTGGCTGTCAGGGCCCCTCTGCGTGATGTATGCTGTGGCCCTTGGG GGAAATACAGTGATCCTGCAGGCTGTGCGAGTGGAGCCCAGCCTCCATGAGCCCATGTAC TACTTCCTGTCCATGTTGTCCTTCAGTGATGTGGCCATATCCATGGCCACACTGCCCACT GTACTCCGAACCTTCTGCCTCAATGCCCGCAACATCACTTTTGATGCCTGTCTAATTCAG ATGTTTCTTATTCACTTCTTCTCCATGATGGAATCAGGTATTCTGCTGGCCATGAGTTTT GACCGCTATGTGGCCATTTGTGACCCCTTGCGCTATGCAACTGTGCTCACCACTGAAGTC ATTGCTGCAATGGGTTTAGGTGCAGCTGCTCGAAGCTTCATCACCCTTTTCCCTCTTCCC TTTCTTATTAAGAGGCTGCCTATCTGCAGATCCAATGTTCTTTCTCACTCCTACTGCCTG CACCCAGACATGATGAGGCTTGCCTGTGCTGATATCAGTATCAACAGCATCTATGGACTC TTTGTTCTTGTATCCACCTTTGGCATGGACCTGTTTTTTATCTTCCTCTCCTATGTGCTC ATTCTGCGTTCTGTCATGGCCACTGCTTCCCGTGAGGAACGCCTCAAAGCTCTCAACACA TGTGTGTCACATATCCTGGCTGTACTTGCATTTTATGTGCCAATGATTGGGGTCTCCACA GTGCACCGCTTTGGGAAGCATGTCCCATGCTACATACATGTCCTCATGTCAAATGTGTAC CTATTTGTGCCTCCTGTGCTCAACCCTCTCATTTATAGCGCCAAGACAAAGGAAATCCGC CGAGCCATTTTCCGCATGTTTCACCACATCAAAATA |
| Conceptual translation |
MGLFNVTHPAFFLLTGIPGLESSHSWLSGPLCVMYAVALGGNTVILQAVRVEPSLHEPMY YFLSMLSFSDVAISMATLPTVLRTFCLNARNITFDACLIQMFLIHFFSMMESGILLAMSF DRYVAICDPLRYATVLTTEVIAAMGLGAAARSFITLFPLPFLIKRLPICRSNVLSHSYCL HPDMMRLACADISINSIYGLFVLVSTFGMDLFFIFLSYVLILRSVMATASREERLKALNT CVSHILAVLAFYVPMIGVSTVHRFGKHVPCYIHVLMSNVYLFVPPVLNPLIYSAKTKEIR RAIFRMFHHIKI Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | T/C | M/T | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | G/T | G/G | 1000GP (YRI, YRI) |
| 11 | 5,453,608 | 5,453,608 | SYN | G/T | G/G | 1000GP (CEU, CHBJPT) |
| 11 | 5,453,888 | 5,453,888 | NS | A/G | T/A | 1000GP (CEU, CHBJPT) |
| 11 | 5,453,940 | 5,453,940 | NS | G/C | R/P | 1000GP (CEU, CHBJPT) |
| 11 | 5,454,275 | 5,454,275 | NS | C/T | R/C | 1000GP (CEU) |
| 11 | 5,454,276 | 5,454,276 | NS | G/A | R/H | 1000GP (CEU, CHBJPT) |
| 11 | 5,454,367 | 5,454,367 | SYN | C/T | S/S | 1000GP (CEU, CHBJPT) |
| 11 | 5,454,385 | 5,454,385 | SYN | C/T | I/I | 1000GP (CHBJPT) |
| 11 | 5,474,838 | 5,474,838 | SYN | G/T | G/G | rs2030094 (DbSNP) |
| 11 | 5,474,894 | 5,474,894 | NS | C/T | T/M | rs74049540 (DbSNP) |
| 11 | 5,475,082 | 5,475,082 | NS | C/T | R/C | rs10450603 (DbSNP) |
| 11 | 5,475,118 | 5,475,118 | NS | A/G | T/A | rs12577167 (DbSNP) |
| 11 | 5,475,170 | 5,475,170 | NS | C/G | P/R | rs16931292 (DbSNP) |
| 11 | 5,475,279 | 5,475,279 | SYN | C/T | L/L | rs10450604 (DbSNP) |
| 11 | 5,475,432 | 5,475,431 | Ins(2) | -/CA | rs35301588 (DbSNP) | |
| 11 | 5,475,433 | 5,475,432 | Ins(2) | -/CA | rs67809969 (DbSNP) | |
| 11 | 5,475,434 | 5,475,433 | Ins(2) | -/CA | rs71053261 (DbSNP) | |
| 11 | 5,475,506 | 5,475,506 | NS | A/G | H/R | rs11037502 (DbSNP) |
| 11 | 5,475,597 | 5,475,597 | SYN | C/T | S/S | rs11037503 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 5,416,622 | 5,492,033 | CopyNumber | Variation_2901 (DGV) |
| 11 | 5,431,984 | 5,493,309 | CopyNumber | Variation_9174 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| M59T | R122C | T134A | R151P | R231C | R263C | R263H | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | M | R | T | R | R | R | R | 56.61 | 0.138 |
| 2 | M | R | A | R | R | R | R | 15.13 | 0.138 |
| 3 | M | R | T | P | R | R | H | 13.06 | 0.138 |
| 4 | T | R | T | R | R | R | R | 6.84 | 0.572 |
| 5 | M | C | T | R | R | R | R | 4.38 | 0.741 |
| 6 | M | R | T | R | R | R | H | 1.54 | 0.138 |
| 7 | M | R | T | R | R | C | R | 1.08 | 0.138 |
| 8 | M | R | T | R | C | R | R | 0.92 | 0.138 |
| 9 | M | C | T | R | C | R | R | 0.31 | 0.741 |
| 10 | M | R | T | P | R | R | R | 0.08 | 0.138 |
| 11 | M | C | T | P | R | R | H | 0.08 | 0.741 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR51I2.aApr07-unspliced | main_exon | CDS | chr11 | 5,453,489 | 5,454,424 | + |
| 3UTR | chr11 | 5,454,424 | 5,454,427 | + | ||