OR5A2 Olfactory Receptor
| Gene Symbol | OR5A21 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.05 (functional) |
| Aliases | OR11-248, HsOR11.13.5, ORL3302, ORL3303 |
| External Ids | HGNC: 15249 GeneBank: AB065805, AF399529, BK004308, NM_001001954 ORDB: ORL3302, ORL3303 |
| Build #39 labels | OR5A2 |
| Chromosomal location | 11:59,421,982-59,422,953 (-) |
| Cluster | 11@59a |
| Synteny | CLIC#27 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5A1 | 67.33% | 303 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5A2B | 85% | 320 |
| Mouse | Or5a21 | 80% | 318 |
| Rat | Or5a21 | 81% | 318 |
| Cow | OR5A22P | 74% | 314 |
| Orang | OR5A1P | 64% | 297 |
| Horse | OR5A2B | 87% | 318 |
| Horse | OR5A2D | 87% | 318 |
| Horse | OR5A2C | 86% | 318 |
| Chimp | OR5A1 | 66% | 304 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136991 |
| GNF Atlas2 | gnf1h02105_at |
Sequence information
| Nucleotide sequence |
ATGGCTGTAGGAAGGAACAACACAATTGTGACAAAATTCATTCTCCTGGGACTTTCAGAC CATCCTCAAATGAAGATTTTCCTTTTCATGTTATTTCTGGGGCTCTACCTCCTGACGTTG GCCTGGAACTTAAGCCTCATTGCCCTCATTAAGATGGACTCTCACCTGCACATGCCCATG TACTTCTTCCTCAGTAACCTGTCCTTCCTGGACATCTGCTATGTGTCCTCCACCGCCCCT AAGATGCTGTCTGACATCATCACAGAGCAGAAAACCATTTCCTTTGTTGGCTGTGCCACT CAGTACTTTGTCTTCTGTGGGATGGGGCTGACTGAATGCTTTCTCCTGGCAGCTATGGCC TATGACCGGTATGCTGCAATCTGCAACCCCTTGCTTTACACAGTCCTCATATCCCATACA CTTTGTTTAAAGATGGTGGTTGGCGCCTATGTGGGTGGATTCCTTAGTTCTTTCATTGAA ACATACTCTGTCTATCAGCATGATTTCTGTGGGCCCTATATGATCAACCACTTTTTCTGT GACCTCCCTCCAGTCCTGGCTCTGTCCTGCTCTGATACCTTCACCAGCGAGGTGGTGACC TTCATAGTCAGTGTTGTCGTTGGAATAGTGTCTGTGCTAGTGGTCCTCATCTCTTATGGT TACATTGTTGCTGCTGTTGTGAAGATCAGCTCAGCTACAGGTAGGACAAAGGCCTTCAGC ACTTGTGCCTCTCACCTGACTGCTGTGACCCTCTTCTATGGTTCTGGATTCTTCATGTAC ATGCGACCCAGTTCCAGCTACTCCCTAAACAGGGACAAGGTGGTGTCCATATTCTATGCC TTGGTGATCCCCGTGGTGAATCCCATCATCTACAGTTTTAGGAATAAGGAGATTAAAAAT GCCATGAGGAAAGCCATGGAAAGGGACCCCGGGATTTCTCACGGTGGACCATTCATTTTT ATGACCTTGGGC |
| Conceptual translation |
MAVGRNNTIVTKFILLGLSDHPQMKIFLFMLFLGLYLLTLAWNLSLIALIKMDSHLHMPM YFFLSNLSFLDICYVSSTAPKMLSDIITEQKTISFVGCATQYFVFCGMGLTECFLLAAMA YDRYAAICNPLLYTVLISHTLCLKMVVGAYVGGFLSSFIETYSVYQHDFCGPYMINHFFC DLPPVLALSCSDTFTSEVVTFIVSVVVGIVSVLVVLISYGYIVAAVVKISSATGRTKAFS TCASHLTAVTLFYGSGFFMYMRPSSSYSLNRDKVVSIFYALVIPVVNPIIYSFRNKEIKN AMRKAMERDPGISHGGPFIFMTLG Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 59,190,252 | 59,190,252 | Del(1) | -/G | rs60923897 (DbSNP) | |
| 11 | 59,190,120 | 59,190,120 | NS | A/G | F/L | rs17153691 (DbSNP) |
| 11 | 59,189,912 | 59,189,912 | NS | A/G | L/P | rs1453547 (DbSNP) |
| 11 | 59,422,647 | 59,422,647 | NS | A/G | F/L | 1000GP (CEU, CHBJPT) |
| 11 | 59,422,439 | 59,422,439 | NS | G/A | P/L | 1000GP (CEU, CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| M302R | P172L | R123Q | F103L | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | M | P | R | F | 79.72 | 0.156 |
| 2 | M | L | R | F | 16.59 | 0.156 |
| 3 | M | P | R | L | 3.30 | 0.156 |
| 4 | R | P | R | F | 0.31 | 0.156 |
| 5 | M | P | Q | F | 0.08 | 0.767 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5A2.aApr07-unspliced | main_exon | 3UTR | chr11 | 59,421,979 | 59,421,982 | - |
| CDS | chr11 | 59,421,982 | 59,422,953 | - | ||