OR5F1 Olfactory Receptor
| Gene Symbol | OR5F11 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | F |
| Pseudogene | No |
| CORP pseudogene probability score | 0.06 (functional) |
| Aliases | OR11-10, OR11-158, OR11-167, OR5F1, HsOR11.11.39, ORL3328 |
| External Ids | HGNC: 8343 GeneBank: AF065863, AF399527, BK004343, BK004722, NM_003697 ORDB: ORL3328 |
| Build #39 labels | OR5F1 |
| Chromosomal location | 11:55,993,684-55,994,625 (-) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5F2P | 91.08% | 314 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5F2 | 84% | 309 |
| Mouse | Or5w1b | 55% | 307 |
| Rat | Or5ap2 | 56% | 304 |
| Cow | OR5F2C | 83% | 314 |
| Cow | OR5F2B | 82% | 314 |
| Cow | OR5F2 | 82% | 314 |
| Orang | OR5E1P | 54% | 310 |
| Horse | OR5F11P | 75% | 302 |
| Chimp | OR5F2 | 92% | 314 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC101241 |
| GNF Atlas2 | gnf1h05456_at |
Sequence information
| Nucleotide sequence |
ATGACCAGAAAAAATTATACCTCACTGACTGAGTTCGTCCTATTGGGATTAGCAGACACG CTGGAGCTACAGATTATCCTCTTTTTGTTTTTTCTTGTGATTTATACACTTACAGTACTG GGAAATCTCGGGATGATCCTCTTAATCAGGATCGATTCCCAGCTTCACACACCCATGTAT TTCTTCCTGGCTAACCTGTCCTTTGTGGACGTTTGTAACTCAACTACCATCACCCCAAAG ATGCTGGCAGATTTATTATCAGAGAAGAAAACCATCTCTTTTGCTGGCTGCTTCCTACAG ATGTACTTCTTTATCTCCCTGGCGACAACCGAATGCATCCTCTTTGGGTTAATGGCCTAT GACAGGTATGCGGCCATATGTCGCCCGCTGCTTTACTCCTTGATCATGTCCAGGACCGTC TACCTAAAAATGGCAGCCGGGGCTTTTGCTGCAGGGTTGCTGAACTTCATGGTCAACACA AGCCATGTCAGCAGCTTGTCATTCTGTGACTCCAATGTCATCCATCACTTCTTCTGTGAC AGTCCCCCACTTTTCAAGCTCTCTTGTTCTGACACAATCCTGAAAGAAAGCATAAGTTCT ATTTTGGCTGGTGTGAATATTGTGGGGACTCTGCTTGTCATCCTCTCCTCCTACTCCTAC GTTCTCTTCTCCATTTTTTCTATGCATTCGGGGGAGGGGAGGCACAGAGCTTTCTCCACG TGTGCCTCTCACCTGACAGCCATAATTCTGTTCTATGCCACCTGCATCTATACTTACCTG AGACCTAGTTCCAGCTACTCCCTGAATCAGGACAAAGTGGCTTCTGTGTTCTACACAGTG GTGATTCCCATGTTGAATCCTCTGATCTACAGCCTCAGGAGTAAGGAAGTAAAGAAGGCT TTAGCGAATGTAATTAGCAGGAAAAGGACCTCTTCCTTTCTG |
| Conceptual translation |
MTRKNYTSLTEFVLLGLADTLELQIILFLFFLVIYTLTVLGNLGMILLIRIDSQLHTPMY FFLANLSFVDVCNSTTITPKMLADLLSEKKTISFAGCFLQMYFFISLATTECILFGLMAY DRYAAICRPLLYSLIMSRTVYLKMAAGAFAAGLLNFMVNTSHVSSLSFCDSNVIHHFFCD SPPLFKLSCSDTILKESISSILAGVNIVGTLLVILSSYSYVLFSIFSMHSGEGRHRAFST CASHLTAIILFYATCIYTYLRPSSSYSLNQDKVASVFYTVVIPMLNPLIYSLRSKEVKKA LANVISRKRTSSFL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 55,761,181 | 55,761,180 | Ins(1) | -/C | rs34761514 (DbSNP) | |
| 11 | 55,761,786 | 55,761,786 | NS | A/C | S/A | rs61888467 (DbSNP) |
| 11 | 55,761,251 | 55,761,251 | NS | A/G | M/T | rs66470326 (DbSNP) |
| 11 | 55,761,270 | 55,761,270 | NS | A/G | Y/H | rs11825964 (DbSNP) |
| 11 | 55,761,338 | 55,761,338 | NS | C/G | C/S | rs58625186 (DbSNP) |
| 11 | 55,761,528 | 55,761,528 | NS | C/T | A/T | rs35607186 (DbSNP) |
| 11 | 55,761,221 | 55,761,221 | NS | T/C | N/S | rs2449134 (DbSNP) |
| 11 | 55,761,328 | 55,761,328 | SYN | A/G | T/T | rs56190402 (DbSNP) |
| 11 | 55,762,060 | 55,762,060 | SYN | C/T | L/L | rs71490418 (DbSNP) |
| 11 | 55,761,738 | 55,761,738 | SYN | G/T | R/R | rs2128152 (DbSNP) |
| 11 | 55,994,310 | 55,994,310 | NS | A/C | S/A | 1000GP (CEU) |
| 11 | 55,994,052 | 55,994,052 | NS | T/C | T/A | 1000GP (CEU, CHBJPT) |
| 11 | 55,993,780 | 55,993,780 | SYN | A/G | I/I | 1000GP (CEU) |
| 11 | 55,994,584 | 55,994,584 | SYN | T/C | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 55,993,775 | 55,993,775 | NS | A/G | M/T | 1000GP (CEU) |
| 11 | 55,993,805 | 55,993,805 | NS | G/A | A/V | 1000GP (CEU) |
| 11 | 100 | -100 | NS | C/T | S/N | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | A/G | I/I | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 55,153,930 | 55,816,828 | CopyNumber | Variation_0308 (DGV) |
| 11 | 55,710,709 | 55,787,839 | CopyNumber | Variation_1245 (DGV) |
| 11 | 55,689,863 | 55,849,156 | CopyNumber | Variation_2927 (DGV) |
| 11 | 54,835,623 | 55,879,426 | CopyNumber | Variation_8690 (DGV) |
| 11 | 55,685,799 | 55,842,512 | CopyNumber | Variation_9189 (DGV) |
| 11 | 55,685,556 | 55,819,544 | CopyNumber | Variation_29912 (DGV), Variation_48846 (DGV) |
| 11 | 55,685,556 | 55,796,170 | CopyNumber | Variation_48845 (DGV) |
| 11 | 55,685,556 | 55,836,620 | CopyNumber | Variation_48847 (DGV) |
| 11 | 55,683,109 | 55,833,490 | CopyNumber | Variation_85786 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| S294N | M284T | Y278H | A274V | C255S | T192A | L166S | S106A | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | N | M | Y | A | C | T | L | S | 79.57 | 0.135 |
| 2 | N | M | Y | A | C | A | L | S | 7.91 | 0.135 |
| 3 | N | M | Y | V | C | T | L | A | 4.15 | 0.135 |
| 4 | S | M | Y | A | C | T | L | S | 3.00 | 0.135 |
| 5 | N | T | Y | A | C | A | L | S | 2.53 | 0.135 |
| 6 | N | M | Y | A | S | T | L | S | 0.77 | 0.135 |
| 7 | N | M | H | A | C | T | L | S | 0.69 | 0.135 |
| 8 | N | M | Y | V | C | T | L | S | 0.54 | 0.135 |
| 9 | N | M | Y | A | C | T | L | A | 0.38 | 0.135 |
| 10 | N | M | Y | A | C | T | S | S | 0.38 | 0.135 |
| 11 | N | T | Y | A | C | T | L | S | 0.08 | 0.135 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5F1.aApr07-unspliced | main_exon | 3UTR | chr11 | 55,993,681 | 55,993,684 | - |
| CDS | chr11 | 55,993,684 | 55,994,625 | - | ||
| 5UTR | chr11 | 55,994,625 | 55,994,627 | - | ||