OR5P3 Olfactory Receptor
| Gene Symbol | OR5P31 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | P |
| Pseudogene | No |
| CORP pseudogene probability score | 0.06 (functional) |
| Aliases | OR11-94, JCG1, HsOR11.5.5, ORL3284 |
| External Ids | HGNC: 14784 GeneBank: AB065770, AF158377, AF399366, BK004321, NM_153445 ORDB: ORL3284 |
| Build #39 labels | OR5P3 |
| Chromosomal location | 11:7,825,040-7,825,972 (-) |
| Cluster | 11@8 |
| Synteny | CLIC#25 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5P1P | 70.74% | 311 |
| OR5P2 | 63.96% | 308 |
| OR5P4P | 66.01% | 303 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5P5 | 72% | 303 |
| Mouse | Or5p80 | 80% | 303 |
| Rat | Or5p80 | 80% | 303 |
| Cow | OR5P1 | 76% | 311 |
| Orang | OR5P1P | 69% | 311 |
| Horse | OR5P3B | 82% | 303 |
| Chimp | OR5P1P | 71% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB463971 |
| GNF Atlas2 | gnf1h08028_at |
Sequence information
| Nucleotide sequence |
ATGGGGACTGGAAATGACACCACTGTGGTAGAGTTTACTCTTTTGGGGTTATCTGAGGAT ACTACAGTTTGTGCTATTTTATTTCTTGTGTTTCTAGGAATTTATGTTGTCACCTTAATG GGTAATATCAGCATAATTGTATTGATCAGAAGAAGTCATCATCTTCATACACCCATGTAC ATTTTCCTCTGCCATTTGGCCTTTGTAGACATTGGGTACTCCTCATCAGTCACACCTGTC ATGCTCATGAGCTTCCTAAGGAAAGAAACCTCTCTCCCTGTTGCTGGTTGTGTGGCCCAG CTCTGTTCTGTAGTGACGTTTGGTACGGCCGAGTGCTTCCTGCTGGCTGCCATGGCCTAT GATCGCTATGTGGCCATCTGCTCACCCCTGCTCTACTCTACCTGCATGTCCCCTGGAGTC TGCATCATCTTAGTGGGCATGTCCTACCTGGGTGGATGTGTGAATGCTTGGACATTCATT GGCTGCTTATTAAGACTGTCCTTCTGTGGGCCAAATAAAGTCAATCACTTTTTCTGTGAC TATTCACCACTTTTGAAGCTTGCTTGTTCCCATGATTTTACTTTTGAAATAATTCCAGCT ATCTCTTCTGGATCTATCATTGTGGCCACTGTGTGTGTCATAGCCATATCCTACATCTAT ATCCTCATCACCATCCTGAAGATGCACTCCACCAAGGGCCGCCACAAGGCCTTCTCCACC TGCACCTCCCACCTCACTGCAGTCACTCTGTTCTATGGGACCATTACCTTCATTTATGTG ATGCCCAAGTCCAGCTACTCAACTGACCAGAACAAGGTGGTGTCTGTGTTCTACACCGTG GTGATTCCCATGTTGAACCCCCTGATCTACAGCCTCAGGAACAAGGAGATTAAGGGGGCT CTGAAGAGAGAGCTTAGAATAAAAATATTTTCT |
| Conceptual translation |
MGTGNDTTVVEFTLLGLSEDTTVCAILFLVFLGIYVVTLMGNISIIVLIRRSHHLHTPMY IFLCHLAFVDIGYSSSVTPVMLMSFLRKETSLPVAGCVAQLCSVVTFGTAECFLLAAMAY DRYVAICSPLLYSTCMSPGVCIILVGMSYLGGCVNAWTFIGCLLRLSFCGPNKVNHFFCD YSPLLKLACSHDFTFEIIPAISSGSIIVATVCVIAISYIYILITILKMHSTKGRHKAFST CTSHLTAVTLFYGTITFIYVMPKSSYSTDQNKVVSVFYTVVIPMLNPLIYSLRNKEIKGA LKRELRIKIFS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | T/C | I/M | 1000GP (YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | A/G | L/L | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 11 | 7,825,325 | 7,825,325 | SYN | T/A | I/I | 1000GP (CEU) |
| 11 | 7,825,333 | 7,825,333 | NS | T/A | I/L | 1000GP (CHBJPT) |
| 11 | 7,825,361 | 7,825,361 | SYN | T/A | G/G | 1000GP (CHBJPT) |
| 11 | 7,825,609 | 7,825,609 | NS | G/A | R/C | 1000GP (CHBJPT) |
| 11 | 7,825,661 | 7,825,661 | SYN | T/C | V/V | 1000GP (CEU, CHBJPT) |
| 11 | 7,825,919 | 7,825,919 | SYN | A/G | S/S | 1000GP (CEU, CHBJPT) |
| 11 | 7,825,925 | 7,825,925 | SYN | C/T | G/G | 1000GP (CEU, CHBJPT) |
| 11 | 7,846,599 | 7,846,599 | NS | T/C | I/M | rs61734816 (DbSNP) |
| 11 | 7,846,689 | 7,846,689 | NS | G/T | F/L | rs450205 (DbSNP) |
| 11 | 7,846,755 | 7,846,755 | SYN | A/G | I/I | rs377363 (DbSNP) |
| 11 | 7,846,767 | 7,846,767 | NS | G/T | F/L | rs364427 (DbSNP) |
| 11 | 7,846,772 | 7,846,772 | NS | C/G | V/L | rs364435 (DbSNP) |
| 11 | 7,846,783 | 7,846,783 | NS | C/G | S/T | rs364444 (DbSNP) |
| 11 | 7,846,941 | 7,846,941 | NS | A/C | F/L | rs73406693 (DbSNP) |
| 11 | 7,846,967 | 7,846,967 | SYN | A/G | L/L | rs61525942 (DbSNP) |
| 11 | 7,847,047 | 7,847,047 | NS | G/T | T/K | rs16932503 (DbSNP) |
| 11 | 7,847,049 | 7,847,049 | NS | C/G | W/C | rs449911 (DbSNP) |
| 11 | 7,847,208 | 7,847,208 | SYN | C/T | V/V | rs1482791 (DbSNP) |
| 11 | 7,847,348 | 7,847,348 | NS | C/G | A/P | rs60467657 (DbSNP) |
| 11 | 7,847,458 | 7,847,458 | NS | G/A | T/I | rs61742097 (DbSNP) |
| 11 | 7,847,466 | 7,847,466 | SYN | A/G | S/S | rs1482792 (DbSNP) |
| 11 | 7,847,472 | 7,847,472 | SYN | C/T | G/G | rs1482793 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 7,806,326 | 7,852,026 | CopyNumber | Variation_35017 (DGV) |
| 11 | 7,844,587 | 7,847,619 | Deletion | #285 (Waszak) |
| 11 | 7,846,597 | 7,847,543 | InDel | Variation_85643 (DGV) |
| 11 | 7,846,698 | 7,847,592 | InDel | Variation_65860 (DGV) |
| 11 | 7,846,855 | 7,847,629 | InDel | Variation_85642 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I307M | T158K | L131F | R122C | P93S | P58A | T21I | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | I | T | L | R | P | P | T | 96.62 | 0.124 |
| 2 | M | T | L | R | P | P | T | 1.54 | 0.124 |
| 3 | I | K | L | R | P | P | I | 0.84 | 0.124 |
| 4 | I | T | F | R | P | P | T | 0.54 | 0.124 |
| 5 | I | T | L | R | P | A | T | 0.23 | 0.232 |
| 6 | I | T | L | R | P | P | I | 0.08 | 0.124 |
| 7 | I | T | L | C | P | P | T | 0.08 | 0.716 |
| 8 | I | T | L | R | S | P | T | 0.08 | 0.124 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5P3.aApr07-unspliced | main_exon | 3UTR | chr11 | 7,825,037 | 7,825,040 | - |
| CDS | chr11 | 7,825,040 | 7,825,972 | - | ||