OR5T2 Olfactory Receptor
| Gene Symbol | OR5T21 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | T |
| Pseudogene | No |
| CORP pseudogene probability score | 0.18 (functional) |
| Aliases | OR11-177, HsOR11.11.54, ORL3296 |
| External Ids | HGNC: 15296 GeneBank: AB065838, BK004334, NM_001004746 ORDB: ORL3296 |
| Build #39 labels | OR5T2 |
| Chromosomal location | 11:56,232,109-56,233,062 (-) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5T1 | 76.92% | 312 |
| OR5T3 | 77.81% | 302 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5T2B | 83% | 311 |
| Mouse | Or5t15 | 75% | 306 |
| Rat | Or5t18 | 73% | 317 |
| Cow | OR5T21 | 79% | 305 |
| Orang | OR9S18 | 52% | 301 |
| Horse | OR5T28 | 78% | 314 |
| Chimp | OR5T2C | 89% | 314 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136876 |
| GNF Atlas2 | gnf1h11079_at |
Sequence information
| Nucleotide sequence |
ATGAAGAATGTCACTGAAGTTACCTTATTTGTACTGAAGGGCTTCACAGACAATCTTGAA CTGCAGACTATCTTCTTCTTCCTGTTTCTAGCAATCTACCTCTTCACTCTCATGGGAAAT TTAGGACTGATTTTAGTGGTCATTAGGGATTCCCAGCTCCACAAACCCATGTACTATTTT CTGAGTATGTTGTCTTCTGTGGATGCCTGCTATTCCTCAGTTATTACCCCAAATATGTTA GTAGATTTTACGACAAAGAATAAAGTCATTTCATTCCTTGGATGTGTAGCACAGGTGTTT CTTGCTTGTAGTTTTGGAACCACAGAATGCTTTCTCTTGGCTGCAATGGCTTATGATCGC TATGTAGCCATCTACAACCCTCTCCTGTATTCAGTGAGCATGTCACCCAGAGTCTACATG CCACTCATCAATGCTTCCTATGTTGCTGGCATTTTACATGCTACTATACATACAGTGGCT ACATTTAGCCTATCCTTCTGTGGAGCCAATGAAATTAGGCGTGTCTTTTGTGATATCCCT CCTCTCCTTGCTATTTCTTATTCTGACACTCACACAAACCAGCTTCTACTCTTCTACTTT GTGGGCTCTATCGAGCTGGTCACTATCCTGATTGTTCTGATCTCCTATGGTTTGATTCTG TTGGCCATTCTGAAGATGTATTCTGCTGAAGGGAGGAGAAAAGTCTTCTCCACATGTGGA GCTCACCTAACTGGAGTGTCAATTTATTATGGGACAATCCTCTTCATGTATGTGAGACCA AGTTCCAGCTATGCTTCGGACCATGACATGATAGTGTCAATATTTTACACCATTGTGATT CCCTTGCTGAATCCCGTCATCTACAGTTTGAGGAACAAAGATGTAAAAGACTCAATGAAA AAAATGTTTGGGAAAAATCAGGTTATCAATAAAGTATATTTTCATACTAAAAAA |
| Conceptual translation |
MKNVTEVTLFVLKGFTDNLELQTIFFFLFLAIYLFTLMGNLGLILVVIRDSQLHKPMYYF LSMLSSVDACYSSVITPNMLVDFTTKNKVISFLGCVAQVFLACSFGTTECFLLAAMAYDR YVAIYNPLLYSVSMSPRVYMPLINASYVAGILHATIHTVATFSLSFCGANEIRRVFCDIP PLLAISYSDTHTNQLLLFYFVGSIELVTILIVLISYGLILLAILKMYSAEGRRKVFSTCG AHLTGVSIYYGTILFMYVRPSSSYASDHDMIVSIFYTIVIPLLNPVIYSLRNKDVKDSMK KMFGKNQVINKVYFHTKK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | G/C | H/D | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | G/A | L/L | 1000GP (YRI) |
| 11 | 55,999,737 | 55,999,737 | NS | C/G | D/H | rs7121880 (DbSNP) |
| 11 | 55,999,897 | 55,999,897 | SYN | A/G | I/I | rs7122000 (DbSNP) |
| 11 | 55,999,950 | 55,999,950 | NS | C/G | V/L | rs12221615 (DbSNP) |
| 11 | 56,000,063 | 56,000,063 | NS | A/C | V/G | rs34616155 (DbSNP) |
| 11 | 56,000,066 | 56,000,066 | NS | G/A | T/I | rs62621278 (DbSNP) |
| 11 | 56,000,288 | 56,000,288 | NS | A/G | M/T | rs7122514 (DbSNP) |
| 11 | 56,000,403 | 56,000,403 | NS | C/G | V/L | rs10791893 (DbSNP) |
| 11 | 56,000,451 | 56,000,451 | SYN | A/G | L/L | rs11227598 (DbSNP) |
| 11 | 56,000,471 | 56,000,471 | NS | A/G | I/T | rs11227599 (DbSNP) |
| 11 | 56,232,202 | 56,232,202 | SYN | G/T | I/I | 1000GP (CHBJPT) |
| 11 | 56,232,261 | 56,232,261 | NS | G/C | H/D | 1000GP (CEU) |
| 11 | 56,232,421 | 56,232,421 | SYN | G/A | I/I | 1000GP (CEU) |
| 11 | 56,232,474 | 56,232,474 | NS | G/C | L/V | 1000GP (CEU, CHBJPT) |
| 11 | 56,232,590 | 56,232,590 | NS | G/A | T/I | 1000GP (CEU) |
| 11 | 56,232,603 | 56,232,603 | NS | C/T | A/T | 1000GP (CEU) |
| 11 | 56,232,812 | 56,232,812 | NS | G/A | T/M | 1000GP (CEU) |
| 11 | 56,232,927 | 56,232,927 | NS | C/G | V/L | 1000GP (CEU) |
| 11 | 56,232,975 | 56,232,975 | SYN | G/A | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 56,232,995 | 56,232,995 | NS | G/A | T/I | 1000GP (CEU, CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| H309D | L238V | S229F | T199I | A195T | T125M | V87L | T64I | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | H | L | S | T | A | T | L | T | 68.97 | 0.940 |
| 2 | H | L | S | T | A | T | V | T | 10.37 | 0.940 |
| 3 | H | V | S | T | A | T | L | I | 9.45 | 0.940 |
| 4 | D | L | S | T | A | M | L | I | 4.84 | 0.940 |
| 5 | H | L | S | I | A | T | L | T | 2.07 | 0.940 |
| 6 | D | L | S | T | A | T | L | I | 1.92 | 0.940 |
| 7 | H | L | S | T | T | T | L | T | 1.08 | 0.940 |
| 8 | H | L | S | T | A | T | L | I | 0.77 | 0.940 |
| 9 | D | L | F | T | A | T | L | I | 0.31 | 0.940 |
| 10 | H | V | S | T | A | M | L | T | 0.08 | 0.940 |
| 11 | D | L | S | T | A | T | L | T | 0.08 | 0.940 |
| 12 | H | L | S | T | A | M | V | T | 0.08 | 0.940 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5T2.aApr07-unspliced | main_exon | 3UTR | chr11 | 56,232,106 | 56,232,109 | - |
| CDS | chr11 | 56,232,109 | 56,233,062 | - | ||
| 5UTR | chr11 | 56,233,062 | 56,233,185 | - | ||