OR5V1 Olfactory Receptor
| Gene Symbol | OR5V11 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | V |
| Pseudogene | No |
| CORP pseudogene probability score | 0.07 (functional) |
| Aliases | OR6-26, hs6M1-21, bA150A6.2, HsOR6.3.17, ORL1029 |
| External Ids | HGNC: 13972 GeneBank: BC069149, BK004440, HSA459859, NM_030876 ORDB: ORL1029 |
| Build #39 labels | OR5V1 |
| Chromosomal location | 6:29,355,233-29,356,195 (-) |
| Cluster | 6@29 |
| Synteny | CLIC#12 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR13D1 | 49.84% | 307 |
| OR5G3P | 49.34% | 302 |
| OR9G4 | 51.29% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR13L2 | 55% | 310 |
| Mouse | Or5v1 | 83% | 316 |
| Mouse | Or5v1b | 83% | 316 |
| Rat | Or5v1b | 82% | 316 |
| Cow | OR5V1C | 81% | 307 |
| Orang | OR10C1 | 52% | 307 |
| Horse | OR5V1D | 83% | 309 |
| Chimp | OR9G4 | 51% | 310 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB463953 |
| GNF Atlas2 | gnf1h00457_at |
Sequence information
| Nucleotide sequence |
ATGGAAAGAAAGAATCAAACAGCTATAACTGAATTCATCATCTTGGGATTCTCCAACCTA AATGAATTGCAGTTTTTACTATTCACCATCTTCTTTCTGACTTATTTCTGTACTTTGGGA GGAAATATATTAATTATCTTGACGACTGTGACTGATCCACACCTGCATACACCTATGTAT TATTTTCTAGGGAACTTGGCCTTTATTGACATCTGCTACACCACCAGCAATGTCCCCCAG ATGATGGTGCACCTCCTCTCAAAGAAAAAAAGCATTTCTTATGTGGGGTGTGTGGTTCAA CTTTTTGCATTTGTTTTCTTTGTAGGATCAGAGTGTCTCCTACTGGCAGCAATGGCATAT GATCGTTACATTGCAATCTGCAATCCTTTAAGGTATTCAGTTATTCTGAGCAAGGTTCTA TGCAATCAATTAGCAGCCTCATGCTGGGCTGCTGGTTTCCTTAACTCAGTGGTGCATACA GTGTTGACATTCTGCCTGCCCTTCTGTGGCAACAATCAGATTAATTACTTCTTCTGTGAC ATCCCCCCTTTGCTGATCTTGTCTTGTGGAAACACTTCTGTCAATGAGTTGGCACTGCTA TCCACTGGGGTCTTCATTGGTTGGACTCCTTTCCTTTGTATCGTACTTTCCTACATTTGC ATAATCTCCACCATCTTGAGGATCCAGTCCTCAGAGGGAAGACGAAAAGCCTTTTCTACA TGTGCCTCCCACCTGGCCATTGTCTTTCTCTTTTATGGCAGCGCCATCTTTACATATGTA CGGCCCATCTCAACTTACTCATTAAAGAAAGATAGGTTGGTTTCAGTGTTGTACAGTGTT GTTACCCCCATGCTAAACCCTATAATTTACACATTGAGGAATAAGGACATCAAAGAAGCT GTCAAAACTATAGGGAGCAAGTGGCAGCCACCAATTTCCTCTTTGGATAGTAAACTCACT TAT |
| Conceptual translation |
MERKNQTAITEFIILGFSNLNELQFLLFTIFFLTYFCTLGGNILIILTTVTDPHLHTPMY YFLGNLAFIDICYTTSNVPQMMVHLLSKKKSISYVGCVVQLFAFVFFVGSECLLLAAMAY DRYIAICNPLRYSVILSKVLCNQLAASCWAAGFLNSVVHTVLTFCLPFCGNNQINYFFCD IPPLLILSCGNTSVNELALLSTGVFIGWTPFLCIVLSYICIISTILRIQSSEGRRKAFST CASHLAIVFLFYGSAIFTYVRPISTYSLKKDRLVSVLYSVVTPMLNPIIYTLRNKDIKEA VKTIGSKWQPPISSLDSKLTY Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 6 | 29,323,905 | 29,323,905 | NS | A/C | L/W | rs6930033 (DbSNP) |
| 6 | 29,323,838 | 29,323,838 | NS | A/C | I/M | rs9257770 (DbSNP) |
| 6 | 29,323,245 | 29,323,245 | NS | C/G | C/S | rs41271546 (DbSNP) |
| 6 | 29,323,276 | 29,323,276 | NS | T/C | R/G | rs61742983 (DbSNP) |
| 6 | 29,323,655 | 29,323,655 | SYN | A/G | F/F | rs7761746 (DbSNP) |
| 6 | 29,323,259 | 29,323,259 | SYN | A/G | F/F | rs3117438 (DbSNP) |
| 6 | 29,323,076 | 29,323,076 | SYN | C/T | E/E | rs9257769 (DbSNP) |
| 6 | 29,323,664 | 29,323,664 | SYN | C/T | A/A | rs28359952 (DbSNP) |
| 6 | 29,355,468 | 29,355,468 | NS | G/C | S/C | 1000GP (CEU) |
| 6 | 29,355,299 | 29,355,299 | SYN | T/C | E/E | 1000GP (CEU, CHBJPT) |
| 6 | 29,355,482 | 29,355,482 | SYN | G/A | F/F | 1000GP (CEU, CHBJPT) |
| 6 | 29,355,878 | 29,355,878 | SYN | G/A | F/F | 1000GP (CEU, CHBJPT) |
| 6 | 29,356,061 | 29,356,061 | NS | A/C | I/M | 1000GP (CEU, CHBJPT) |
| 6 | 29,356,128 | 29,356,128 | NS | A/C | L/W | 1000GP (CEU, CHBJPT) |
| 6 | 29,355,887 | 29,355,887 | SYN | T/C | A/A | 1000GP (CHBJPT) |
| 6 | 100 | -100 | SYN | G/A | F/F | 1000GP (YRI, YRI) |
| 6 | 100 | -100 | NS | C/T | G/R | 1000GP (YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| S243C | G233R | I46V | I45M | L23W | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | S | G | I | I | L | 67.20 | 0.217 |
| 2 | S | G | I | I | W | 22.96 | 0.217 |
| 3 | S | R | I | I | L | 6.68 | 0.183 |
| 4 | S | G | I | M | L | 2.61 | 0.217 |
| 5 | C | G | I | I | L | 0.31 | 0.044 |
| 6 | S | G | V | I | L | 0.23 | 0.217 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR11A1andOR5V1.bApr07 | main_exon | 3UTR | chr6 | 29,355,229 | 29,355,233 | - |
| CDS | chr6 | 29,355,233 | 29,356,195 | - | ||
| 5UTR | chr6 | 29,356,195 | 29,356,277 | - | ||