OR6N1 Olfactory Receptor
| Gene Symbol | OR6N11 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | N |
| Pseudogene | No |
| CORP pseudogene probability score | 0.05 (functional) |
| Aliases | OR1-22, HsOR1.4.17, ORL3019 |
| External Ids | HGNC: 15034 GeneBank: AB065631, AF399608, BK004199, NM_001005185 ORDB: ORL3019 |
| Build #39 labels | OR6N1 |
| Chromosomal location | 1:158,765,747-158,766,682 (-) |
| Cluster | 1@159a |
| Synteny | CLIC#4 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6N2 | 66.34% | 309 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6N2 | 70% | 309 |
| Mouse | Or6n1 | 89% | 311 |
| Rat | Or6n1 | 88% | 312 |
| Cow | OR6N2 | 67% | 309 |
| Orang | OR6N1BP | 94% | 268 |
| Horse | OR6N2 | 68% | 305 |
| Chimp | OR6N2 | 66% | 309 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC146847 |
Sequence information
| Nucleotide sequence |
ATGGACACAGGGAACTGGAGCCAGGTAGCAGAATTCATCATCTTGGGCTTCCCCCATCTC CAGGGTGTCCAGATTTATCTCTTCCTCTTGTTGCTTCTCATTTACCTCATGACTGTGTTG GGAAACCTGCTGATATTCCTGGTGGTCTGCCTGGACTCCCGGCTTCACACACCCATGTAC CACTTTGTCAGCATTCTCTCCTTCTCAGAGCTTGGCTATACAGCTGCCACCATCCCTAAG ATGCTGGCAAACTTGCTCAGTGAGAAAAAGACCATTTCATTCTCTGGGTGTCTCCTGCAG ATCTATTTCTTTCACTCCCTTGGAGCGACTGAGTGCTATCTCCTGACAGCTATGGCCTAC GATAGGTATTTAGCCATCTGCCGGCCCCTCCACTACCCAACCCTCATGACCCCAACACTT TGTGCAGAGATTGCCATTGGCTGTTGGTTGGGAGGCTTGGCTGGGCCAGTAGTTGAAATT TCCTTGATTTCACGCCTCCCATTCTGTGGCCCCAATCGCATTCAGCACGTCTTTTGTGAC TTCCCTCCTGTGCTGAGTTTGGCTTGCACTGATACGTCTATAAATGTCCTAGTAGATTTT GTTATAAATTCCTGCAAGATCCTAGCCACCTTCCTGCTGATCCTCTGCTCCTATGTGCAG ATCATCTGCACAGTGCTCAGAATTCCCTCAGCTGCCGGCAAGAGGAAGGCCATCTCCACG TGTGCCTCCCACTTCACTGTGGTTCTCATCTTCTATGGGAGCATCCTTTCCATGTATGTG CAGCTGAAGAAGAGCTACTCACTGGACTATGACCAGGCCCTGGCAGTGGTCTACTCAGTG CTCACACCCTTCCTCAACCCCTTCATCTACAGCTTGCGCAACAAGGAGATCAAGGAGGCT GTGAGGAGGCAGCTAAAGAGAATTGGGATATTGGCA |
| Conceptual translation |
MDTGNWSQVAEFIILGFPHLQGVQIYLFLLLLLIYLMTVLGNLLIFLVVCLDSRLHTPMY HFVSILSFSELGYTAATIPKMLANLLSEKKTISFSGCLLQIYFFHSLGATECYLLTAMAY DRYLAICRPLHYPTLMTPTLCAEIAIGCWLGGLAGPVVEISLISRLPFCGPNRIQHVFCD FPPVLSLACTDTSINVLVDFVINSCKILATFLLILCSYVQIICTVLRIPSAAGKRKAIST CASHFTVVLIFYGSILSMYVQLKKSYSLDYDQALAVVYSVLTPFLNPFIYSLRNKEIKEA VRRQLKRIGILA Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 158,736,217 | 158,736,217 | NS | A/G | F/L | rs857828 (DbSNP) |
| 1 | 158,735,892 | 158,735,892 | NS | A/G | I/T | rs857827 (DbSNP) |
| 1 | 158,736,201 | 158,736,201 | NS | A/G | I/T | rs7521578 (DbSNP) |
| 1 | 158,735,740 | 158,735,740 | NS | A/G | F/L | rs857826 (DbSNP) |
| 1 | 158,736,445 | 158,736,445 | NS | C/T | A/T | rs1864346 (DbSNP) |
| 1 | 158,735,691 | 158,735,691 | NS | C/T | R/Q | rs857825 (DbSNP) |
| 1 | 158,735,595 | 158,735,595 | NS | C/T | R/H | rs857824 (DbSNP) |
| 1 | 158,736,215 | 158,736,215 | SYN | A/G | L/L | rs6666753 (DbSNP) |
| 1 | 158,765,805 | 158,765,805 | NS | C/T | R/H | 1000GP (CEU, CHBJPT) |
| 1 | 158,765,950 | 158,765,950 | NS | A/G | F/L | 1000GP (CEU, CHBJPT) |
| 1 | 158,766,425 | 158,766,425 | SYN | G/A | L/L | 1000GP (CEU, CHBJPT) |
| 1 | 158,766,115 | 158,766,115 | NS | T/G | T/P | 1000GP (CEU) |
| 1 | 158,765,901 | 158,765,901 | NS | T/C | Q/R | 1000GP (CEU, CHBJPT) |
| 1 | 158,766,655 | 158,766,655 | NS | C/T | A/T | 1000GP (CEU, CHBJPT) |
| 1 | 158,766,102 | 158,766,102 | NS | A/G | I/T | 1000GP (CEU, CHBJPT) |
| 1 | 100 | -100 | NS | C/T | R/H | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | G/A | L/L | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 158,733,537 | 158,736,572 | Deletion | #180 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R293H | Q261R | F245L | I194T | T190P | C169Y | T91I | L86F | A10T | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | H | R | L | T | T | C | T | L | A | 41.09 | 0.105 |
| 2 | R | Q | F | I | T | C | T | L | A | 28.88 | 0.105 |
| 3 | H | R | L | T | T | C | T | L | T | 26.80 | 0.105 |
| 4 | H | R | L | T | T | C | I | L | A | 1.54 | 0.105 |
| 5 | H | R | L | T | T | Y | T | L | A | 0.46 | 0.105 |
| 6 | H | R | L | T | P | C | T | L | A | 0.38 | 0.105 |
| 7 | H | R | L | T | T | C | T | F | A | 0.31 | 0.105 |
| 8 | H | Q | F | I | T | C | T | L | A | 0.23 | 0.105 |
| 9 | R | R | L | T | T | C | T | L | T | 0.15 | 0.105 |
| 10 | R | R | L | T | T | C | T | L | A | 0.08 | 0.105 |
| 11 | H | Q | L | T | T | C | T | L | T | 0.08 | 0.105 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6N1.aApr07-unspliced | main_exon | 3UTR | chr1 | 158,765,744 | 158,765,747 | - |
| CDS | chr1 | 158,765,747 | 158,766,682 | - | ||