OR6X1 Olfactory Receptor
| Gene Symbol | OR6X11 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | X |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | OR11-270, HsOR11.18.1, ORL3438 |
| External Ids | HGNC: 14737 GeneBank: AB065510, BK004362, NM_001005188 ORDB: ORL3438 |
| Build #39 labels | OR6X1 |
| Chromosomal location | 11:123,753,583-123,754,518 (-) |
| Cluster | 11@124 |
| Synteny | CLIC#29 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6F1 | 48.83% | 299 |
| OR6M1 | 48.18% | 303 |
| OR6M2P | 48.36% | 304 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6M2 | 52% | 303 |
| Mouse | Or6x1 | 85% | 312 |
| Rat | Or6x1 | 84% | 312 |
| Cow | OR6M7 | 52% | 304 |
| Orang | OR6M2P | 49% | 304 |
| Horse | OR6M8 | 53% | 303 |
| Chimp | OR6M2P | 48% | 304 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136856 |
| GNF Atlas2 | gnf1h02119_at |
Sequence information
| Nucleotide sequence |
ATGAGAAATGGCACAGTAATCACAGAATTCATCCTGCTAGGCTTTCCTGTTATCCAAGGC CTACAAACACCTCTCTTTATTGCAATCTTTCTCACCTACATATTAACCCTTGCAGGCAAT GGGCTTATTATTGCCACTGTGTGGGCTGAGCCCAGGCTACAAATTCCAATGTACTTCTTC CTTTGTAACTTGTCTTTCTTAGAAATCTGGTACACCACCACAGTCATCCCCAAACTGCTA GGAACCTTTGTAGTGGCAAGAACAGTAATCTGCATGTCCTGCTGCCTGCTGCAGGCCTTC TTCCACTTCTTCGTGGGCACCACCGAGTTCTTGATCCTCACTATCATGTCTTTTGACCGC TACCTCACCATCTGCAATCCCCTTCACCACCCCACCATCATGACCAGCAAACTCTGCCTG CAGCTGGCCCTGAGCTCCTGGGTGGTGGGCTTCACCATTGTCTTTTGTCAGACGATGCTG CTCATCCAGTTGCCATTCTGTGGCAATAATGTTATCAGTCATTTCTACTGTGATGTTGGG CCCAGTTTGAAAGCCGCCTGCATAGACACCAGCATTTTGGAACTCCTGGGCGTCATAGCA ACCATCCTTGTGATCCCAGGGTCACTTCTCTTTAATATGATTTCTTATATCTACATTCTG TCCGCAATCCTACGAATTCCTTCAGCCACTGGCCACCAAAAGACTTTCTCTACCTGTGCC TCGCACCTGACAGTTGTCTCCCTGCTCTACGGGGCTGTTCTGTTCATGTACCTAAGACCC ACAGCACACTCCTCCTTTAAGATTAATAAGGTGGTGTCTGTGCTAAATACTATCCTCACC CCCCTTCTGAATCCCTTTATTTATACTATTAGAAACAAGGAGGTGAAGGGAGCCTTAAGA AAGGCAATGACTTGCCCAAAGACTGGTCATGCAAAG |
| Conceptual translation |
MRNGTVITEFILLGFPVIQGLQTPLFIAIFLTYILTLAGNGLIIATVWAEPRLQIPMYFF LCNLSFLEIWYTTTVIPKLLGTFVVARTVICMSCCLLQAFFHFFVGTTEFLILTIMSFDR YLTICNPLHHPTIMTSKLCLQLALSSWVVGFTIVFCQTMLLIQLPFCGNNVISHFYCDVG PSLKAACIDTSILELLGVIATILVIPGSLLFNMISYIYILSAILRIPSATGHQKTFSTCA SHLTVVSLLYGAVLFMYLRPTAHSSFKINKVVSVLNTILTPLLNPFIYTIRNKEVKGALR KAMTCPKTGHAK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 123,624,658 | 123,624,658 | NS | G/T | T/N | rs12364099 (DbSNP) |
| 11 | 123,753,950 | 123,753,950 | NS | G/T | T/N | 1000GP (CEU, CHBJPT) |
| 11 | 100 | -100 | SYN | G/C | P/P | 1000GP (YRI, YRI) |
| 11 | 100 | -100 | NS | T/C | I/V | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 59 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I268V | A229G | T190N | A185V | R120C | T74I | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | I | A | T | A | R | T | 88.94 | 1.000 |
| 2 | I | A | N | A | R | T | 8.53 | 1.000 |
| 3 | V | A | T | A | R | T | 1.46 | 1.000 |
| 4 | I | G | T | A | R | I | 0.46 | 1.000 |
| 5 | I | A | T | V | R | T | 0.38 | 1.000 |
| 6 | I | A | T | A | C | T | 0.23 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6X1.aApr07-unspliced | main_exon | 3UTR | chr11 | 123,753,580 | 123,753,583 | - |
| CDS | chr11 | 123,753,583 | 123,754,518 | - | ||