OR7G3 Olfactory Receptor
| Gene Symbol | OR7G31 (View this gene in GeneCards) |
| Family | 7 |
| Subfamily | G |
| Pseudogene | No |
| CORP pseudogene probability score | 0.12 (functional) |
| Aliases | OR19-9, OST085, HsOR19.2.7, ORL37465 |
| External Ids | HGNC: 8467 GeneBank: AB065932, AF399540, BK004266, NM_001001958 ORDB: ORL37465 |
| Build #39 labels | OR7G3 |
| Chromosomal location | 19:9,126,015-9,126,950 (-) |
| Cluster | 19@9b |
| Synteny | CLIC#42 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR7D4 | 65.16% | 310 |
| OR7G1 | 67.1% | 307 |
| OR7G2 | 68.39% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR7G7 | 73% | 305 |
| Mouse | Or7g12 | 78% | 310 |
| Rat | Or7g12 | 77% | 310 |
| Cow | OR7G7 | 72% | 305 |
| Orang | OR7G3P | 93% | 312 |
| Horse | OR7G3P | 81% | 305 |
| Chimp | OR7G3P | 96% | 305 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h11268_at |
Sequence information
| Nucleotide sequence |
ATGAAAGCAGGAAACTTCTCAGACACTCCAGAATTCTTTCTCTTGGGATTGTCAGGGGAT CCGGAGCTGCAGCCCATCCTCTTCATGCTGTTCCTGTCCATGTACCTGGCCACAATGCTG GGGAACCTGCTCATCATCCTGGCCGTCAACTCTGACTCCCACCTCCACACCCCCATGTAC TTCCTCCTCTCTATCCTGTCCTTGGTCGACATCTGTTTCACCTCCACCACGATGCCCAAG ATGCTGGTGAACATCCAGGCACAGGCTCAATCCATCAATTACACAGGCTGCCTCACCCAA ATCTGCTTTGTCCTGGTTTTTGTTGGATTGGAAAATGGAATTCTGGTCATGATGGCCTAT GATCGATTTGTGGCCATCTGTCACCCACTGAGGTACAATGTCATCATGAACCCCAAACTC TGTGGGCTGCTGCTTCTGCTGTCCTTCATCGTTAGTGTCCTGGATGCTCTGCTGCACACG TTGATGGTGCTACAGCTGACCTTCTGCATAGACCTGGAAATTCCCCACTTTTTCTGTGAA CTAGCTCATATTCTCAAGCTCGCCTGTTCTGATGTCCTCATCAATAACATCCTGGTGTAT TTGGTGACCAGCCTGTTAGGTGTTGTTCCTCTCTCTGGGATCATTTTCTCTTACACACGA ATTGTCTCCTCTGTCATGAAAATTCCATCAGCTGGTGGAAAGTATAAAGCTTTTTCCATC TGCGGGTCACATTTAATCGTTGTTTCCTTGTTTTATGGAACAGGGTTTGGGGTGTACCTT AGTTCTGGGGCTACCCACTCCTCCAGGAAGGGTGCAATAGCATCAGTGATGTATACCGTG GTCACCCCCATGCTGAACCCACTCATTTACAGCCTGAGAAACAAGGACATGTTGAAGGCT TTGAGGAAACTAATATCTAGGATACCATCTTTCCAT |
| Conceptual translation |
MKAGNFSDTPEFFLLGLSGDPELQPILFMLFLSMYLATMLGNLLIILAVNSDSHLHTPMY FLLSILSLVDICFTSTTMPKMLVNIQAQAQSINYTGCLTQICFVLVFVGLENGILVMMAY DRFVAICHPLRYNVIMNPKLCGLLLLLSFIVSVLDALLHTLMVLQLTFCIDLEIPHFFCE LAHILKLACSDVLINNILVYLVTSLLGVVPLSGIIFSYTRIVSSVMKIPSAGGKYKAFSI CGSHLIVVSLFYGTGFGVYLSSGATHSSRKGAIASVMYTVVTPMLNPLIYSLRNKDMLKA LRKLISRIPSFH Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 19 | 100 | -100 | nonsense SNP | G/A | R/* | 1000GP (YRI, YRI) |
| 19 | 100 | -100 | NS | C/T | V/I | 1000GP (YRI, YRI, YRI, YRI) |
| 19 | 100 | -100 | SYN | A/G | V/V | 1000GP (YRI, YRI, YRI) |
| 19 | 9,126,048 | 9,126,048 | NS | C/G | L/F | 1000GP (CHBJPT) |
| 19 | 9,126,210 | 9,126,210 | SYN | A/G | V/V | 1000GP (CEU, CHBJPT) |
| 19 | 9,126,212 | 9,126,212 | NS | C/T | V/I | 1000GP (CHBJPT) |
| 19 | 9,126,293 | 9,126,293 | nonsense SNP | G/A | R/* | 1000GP (CHBJPT) |
| 19 | 9,126,654 | 9,126,654 | SYN | G/A | T/T | 1000GP (CEU) |
| 19 | 9,126,759 | 9,126,759 | SYN | A/G | S/S | 1000GP (CEU, CHBJPT) |
| 19 | 9,126,760 | 9,126,760 | NS | G/A | S/F | 1000GP (CHBJPT) |
| 19 | 9,126,781 | 9,126,781 | NS | G/T | T/N | 1000GP (CHBJPT) |
| 19 | 9,126,843 | 9,126,843 | SYN | C/T | L/L | 1000GP (CHBJPT) |
| 19 | 9,126,866 | 9,126,866 | NS | T/C | M/V | 1000GP (CEU, CHBJPT) |
| 19 | 9,126,946 | 9,126,946 | NS | T/C | K/R | 1000GP (CHBJPT) |
| 19 | 9,236,706 | 9,236,705 | Ins(5) | -/GGTAT | rs3029651 (DbSNP) | |
| 19 | 9,236,707 | 9,236,706 | Ins(5) | -/GGTAT | rs34694385 (DbSNP) | |
| 19 | 9,236,886 | 9,236,886 | SYN | A/G | V/V | rs10424352 (DbSNP) |
| 19 | 9,236,888 | 9,236,888 | NS | T/C | I/V | rs61730396 (DbSNP) |
| 19 | 9,236,917 | 9,236,917 | NS | A/G | V/A | rs61730387 (DbSNP) |
| 19 | 9,236,969 | 9,236,969 | nonsense SNP | G/A | R/* | rs61751875 (DbSNP) |
| 19 | 9,237,263 | 9,237,263 | nonsense SNP | A/G | */R | rs17001893 (DbSNP) |
| 19 | 9,237,435 | 9,237,435 | SYN | A/G | S/S | rs10407484 (DbSNP) |
| 19 | 9,237,436 | 9,237,436 | NS | G/A | S/F | rs61745558 (DbSNP) |
| 19 | 9,237,542 | 9,237,542 | NS | C/T | V/M | rs10414255 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 19 | 9,234,691 | 9,237,726 | Deletion | #246 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| L301F | V247I | R220* | L172V | R122* | T57N | M29V | K2R | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | L | V | R | L | R | T | M | K | 54.45 | 0.239 |
| 2 | L | V | R | L | R | T | V | K | 38.63 | 0.239 |
| 3 | L | I | * | L | R | T | V | R | 2.38 | 1.200 |
| 4 | L | V | R | L | * | T | M | K | 1.77 | 1.200 |
| 5 | L | I | * | L | R | N | V | R | 1.08 | 1.200 |
| 6 | L | I | * | L | R | T | V | K | 0.54 | 1.200 |
| 7 | F | V | R | L | R | T | V | K | 0.54 | 0.239 |
| 8 | L | I | * | L | R | N | M | R | 0.23 | 1.200 |
| 9 | L | V | * | L | R | N | V | R | 0.08 | 1.200 |
| 10 | L | I | R | L | R | T | V | K | 0.08 | 0.286 |
| 11 | L | V | R | V | R | T | V | K | 0.08 | 0.239 |
| 12 | L | V | R | L | * | T | V | K | 0.08 | 1.200 |
| 13 | L | V | R | L | R | T | M | R | 0.08 | 0.239 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR7G3.aApr07-unspliced | main_exon | 3UTR | chr19 | 9,126,012 | 9,126,015 | - |
| CDS | chr19 | 9,126,015 | 9,126,950 | - | ||