OR8D1 Olfactory Receptor
| Gene Symbol | OR8D11 (View this gene in GeneCards) |
| Family | 8 |
| Subfamily | D |
| Pseudogene | No |
| CORP pseudogene probability score | 0.05 (functional) |
| Aliases | JCG9, OST004, pDJ9j14, OR11-301, HsOR11.18.26, ORL3317 |
| External Ids | HGNC: 8481 GeneBank: AB065828, AF238489, BK004501, NM_001002917 ORDB: ORL3317 |
| Build #39 labels | OR8D1 |
| Chromosomal location | 11:124,309,843-124,310,766 (-) |
| Cluster | 11@124 |
| Synteny | CLIC#29 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR8D2 | 70.13% | 308 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR8D2 | 73% | 308 |
| Mouse | Or8d1 | 85% | 308 |
| Mouse | Or8d1b | 85% | 308 |
| Rat | Or8d1f-ps | 82% | 308 |
| Rat | Or8d1e-ps | 82% | 308 |
| Rat | Or8d1d-ps | 82% | 308 |
| Rat | Or8d1g-ps | 82% | 308 |
| Cow | OR8D2P | 74% | 308 |
| Orang | OR8D2 | 70% | 308 |
| Horse | OR8D2 | 73% | 304 |
| Chimp | OR8D2 | 69% | 308 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AF238489 |
Sequence information
| Nucleotide sequence |
ATGACCATGGAAAATTATTCTATGGCAGCTCAGTTTGTCTTAGATGGTTTAACACAGCAA GCAGAGCTCCAGCTGCCCCTCTTCCTCCTGTTCCTGGGAATCTATGTGGTCACAGTAGTG GGCAACCTGGGCATGATTCTCCTGATTGCAGTCAGCCCTCTACTTCACACCCCCATGTAC TATTTCCTCAGCAGCTTGTCCTTCGTCGATTTCTGCTATTCCTCTGTCATTACTCCCAAA ATGCTGGTGAACTTCCTAGGAAAGAAGAATACAATCCTTTACTCTGAGTGCATGGTCCAG CTCTTTTTCTTTGTGGTCTTTGTGGTGGCTGAGGGTTACCTCCTGACTGCCATGGCATAT GATCGCTATGTTGCCATCTGTAGCCCACTGCTTTATAATGCGATCATGTCCTCATGGGTC TGCTCACTGCTAGTGCTGGCTGCCTTCTTCTTGGGCTTTCTCTCTGCCTTGACTCATACA AGTGCCATGATGAAACTGTCCTTTTGCAAATCCCACATTATCAACCATTACTTCTGTGAT GTTCTTCCCCTCCTCAATCTCTCCTGCTCCAACACACACCTCAATGAGCTTCTACTTTTT ATCATTGCGGGGTTTAACACCTTGGTGCCCACCCTAGCTGTTGCTGTCTCCTATGCCTTC ATCCTCTACAGCATCCTTCACATCCGCTCCTCAGAGGGCCGGTCCAAAGCTTTTGGAACA TGCAGCTCTCATCTCATGGCTGTGGTGATCTTCTTTGGGTCCATTACCTTCATGTATTTC AAGCCCCCTTCAAGTAACTCCCTGGACCAGGAGAAGGTGTCCTCTGTGTTCTACACCACG GTGATCCCCATGCTGAACCCTTTAATATACAGTCTGAGGAATAAGGATGTGAAGAAAGCA TTAAGGAAGGTCTTAGTAGGAAAA |
| Conceptual translation |
MTMENYSMAAQFVLDGLTQQAELQLPLFLLFLGIYVVTVVGNLGMILLIAVSPLLHTPMY YFLSSLSFVDFCYSSVITPKMLVNFLGKKNTILYSECMVQLFFFVVFVVAEGYLLTAMAY DRYVAICSPLLYNAIMSSWVCSLLVLAAFFLGFLSALTHTSAMMKLSFCKSHIINHYFCD VLPLLNLSCSNTHLNELLLFIIAGFNTLVPTLAVAVSYAFILYSILHIRSSEGRSKAFGT CSSHLMAVVIFFGSITFMYFKPPSSNSLDQEKVSSVFYTTVIPMLNPLIYSLRNKDVKKA LRKVLVGK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | G/A | S/F | 1000GP (YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | C/T | V/V | 1000GP (YRI) |
| 11 | 124,179,835 | 124,179,835 | SYN | C/T | V/V | rs4936918 (DbSNP) |
| 11 | 124,179,902 | 124,179,902 | NS | A/G | F/S | rs57552127 (DbSNP) |
| 11 | 124,180,063 | 124,180,063 | Del(1) | -/A | rs34197526 (DbSNP) | |
| 11 | 124,180,082 | 124,180,082 | NS | A/G | L/P | rs4936919 (DbSNP) |
| 11 | 124,180,173 | 124,180,172 | Ins(1) | -/T | rs36031700 (DbSNP) | |
| 11 | 124,180,282 | 124,180,282 | NS | A/C | C/W | rs7107539 (DbSNP) |
| 11 | 124,180,359 | 124,180,359 | NS | C/A | V/F | rs2510433 (DbSNP) |
| 11 | 124,180,477 | 124,180,477 | SYN | A/G | F/F | rs6590057 (DbSNP) |
| 11 | 124,309,939 | 124,309,939 | SYN | C/T | V/V | 1000GP (CEU, CHBJPT) |
| 11 | 124,310,006 | 124,310,006 | NS | G/A | S/F | 1000GP (CHBJPT) |
| 11 | 124,310,186 | 124,310,186 | NS | A/G | L/P | 1000GP (CEU, CHBJPT) |
| 11 | 124,310,386 | 124,310,386 | NS | A/C | C/W | 1000GP (CEU, CHBJPT) |
| 11 | 124,310,581 | 124,310,581 | SYN | G/A | F/F | 1000GP (CEU) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| S254F | I201T | L194P | C127W | F102V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | S | I | L | C | F | 54.84 | 0.199 |
| 2 | S | I | P | W | F | 29.95 | 0.199 |
| 3 | F | I | L | C | F | 11.29 | 0.199 |
| 4 | S | I | P | C | F | 1.84 | 0.199 |
| 5 | S | T | L | C | F | 1.23 | 0.199 |
| 6 | S | I | L | C | V | 0.77 | 0.199 |
| 7 | S | I | P | W | V | 0.08 | 0.199 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR8D1.aApr07-unspliced | main_exon | 3UTR | chr11 | 124,309,840 | 124,309,843 | - |
| CDS | chr11 | 124,309,843 | 124,310,766 | - | ||