OR8G1 Olfactory Receptor
| Gene Symbol | OR8G11 (View this gene in GeneCards) |
| Family | 8 |
| Subfamily | G |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | OR11-296, HSTPCR25, OR11-281, HsOR11.18.24P, ORL209 |
| External Ids | HGNC: 8484 GeneBank: AB065946, AF399507, BK004423, BK004659, HSTPCR25P, NM_001002905, XM_499553 ORDB: ORL209 |
| Build #39 labels | OR8G1 |
| Chromosomal location | 11:124,249,676-124,251,438 (+) |
| Cluster | 11@124 |
| Synteny | CLIC#29 |
| Remarks | Segregating Pseudo Gene, a nonsynonymous SNP rs4268525 (AA change=Y/* ) |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR8G5 | 82% | 311 |
| Mouse | Or8g23 | 79% | 308 |
| Rat | Or8g20 | 77% | 311 |
| Cow | OR8G5B | 82% | 311 |
| Cow | OR8G5 | 80% | 311 |
| Orang | OR8G3G | 79% | 308 |
| Horse | OR8G5C | 86% | 311 |
| Chimp | OR8G5 | 87% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | X89672 |
Sequence information
| Nucleotide sequence |
ATGTCAGGAGAAAATAATTCCTCAGTGACTGAGTTCATTCTGGCTGGGCTCTCAGAACAG CCAGAGCTCCAGCTGCCCCTCTTCCTCCTGTTCTTAGGAATCTATGTGGTCACAGTGGTG GGCAACCTGGGCATGACCACACTGATTTGGCTCAGTTCTCACCTGCACACCCCTATGTAC TATTTCCTCAGCAGTCTGTCCTTCATTGACTTCTGCCATTCCACTGTCATTACCCCTAAG ATGCTGGTGAACTTTGTGACAGAGAAGAACATCATCTCCTACCCTGAATGCATGACTCAG CTCTACTTCTTCCTCGTTTTTGCTATTGCAGAGTGTCACATGTTGGCTGCAATGGCGTAT GACCGTTACATGGCCATCTGTAGCCCCTTGCTGTACAGTGTCATCATATCCAATAAGGCT TGCTTTTCTCTGATTTTAGGGGTGTATATAATAGGCCTGGTTTGTGCATCAGTTCATACA GGCTGTATGTTTAGGGTTCAATTCTGCAAATTTGATTTGATTAACCATTATTTCTGTGAT CTTCTTCCCCTCCTAAAGCTCTCTTGCTCTAGTATCTATGTCAACAAACTACTTATTCTA TGTGTTGGTGCATTTAACATCCTTGTCCCCAGCCTGACCATCCTTTGCTCTTACATCTTT ATTATTGCCAGCATCCTCCACATTCGCTCCACTGAGGGCAGGTCCAAAGCCTTCAGCACT TGTAGCTCCCACATGTTGGCGGTTGTAATCTTTTTTGGATCTGCAGCATTCATGTAGTTG CAGCCATCTTCAATCAGCTCCATGGACCAGGGGAAAGTATCCTCTGTGTTTTATACTATT ATTGTGCCCATGTTGAACCCTCTGAGCTACATATGTTTTTAAATCTAATCTAATTTAATT TATATTTCAAGT |
| Conceptual translation |
Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | nonsense SNP | G/C | */Y | 1000GP (YRI) |
| 11 | 100 | -100 | NS | A/G | S/G | 1000GP (YRI, YRI) |
| 11 | 100 | -100 | SYN | T/C | S/S | 1000GP (YRI, YRI) |
| 11 | 124,120,821 | 124,120,821 | SYN | C/T | S/S | rs12099154 (DbSNP) |
| 11 | 124,121,162 | 124,121,162 | NS | C/T | A/V | rs4482039 (DbSNP) |
| 11 | 124,121,199 | 124,121,199 | nonsense SNP | C/G | Y/* | rs4268525 (DbSNP) |
| 11 | 124,121,288 | 124,121,287 | Ins(851) | Ins | rs71019875 (DbSNP) | |
| 11 | 124,250,074 | 124,250,074 | SYN | T/C | S/S | 1000GP (CEU, CHBJPT) |
| 11 | 124,250,415 | 124,250,415 | NS | C/T | A/V | 1000GP (CHBJPT) |
| 11 | 124,250,452 | 124,250,452 | nonsense SNP | G/C | */Y | 1000GP (CEU) |
| 11 | 124,250,452 | 124,251,303 | nonsense SNP | G/C | */Y | 1000GP (CHBJPT) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 124,109,057 | 124,122,118 | CopyNumber | Variation_71393 (DGV) |
| 11 | 124,121,285 | 124,121,286 | CopyNumber | Variation_41258 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| Y35C | S133G | *259Y | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | Y | S | * | 51.46 | 1.200 |
| 2 | Y | S | Y | 48.31 | 0.377 |
| 3 | Y | G | Y | 0.15 | 0.377 |
| 4 | C | S | Y | 0.08 | 0.678 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR8G1.aApr07-unspliced | main_exon | CDS_partial | chr11 | 124,250,050 | 124,250,521 | + |