OR8K1 Olfactory Receptor
| Gene Symbol | OR8K11 (View this gene in GeneCards) |
| Family | 8 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.84 (pseudogene) |
| Aliases | OR11-182, HsOR11.11.61, ORL3321 |
| External Ids | HGNC: 14831 GeneBank: AB065835, AF399517, BK004339, NM_001002907, XM_372396 ORDB: ORL3321 |
| Build #39 labels | OR8K1 |
| Chromosomal location | 11:56,346,039-56,346,995 (+) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR8K3 | 68.83% | 308 |
| OR8K5 | 64.29% | 308 |
| OR8V1P | 66.56% | 305 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR8K71 | 68% | 312 |
| Mouse | Or8k1 | 82% | 312 |
| Rat | Or8k1 | 82% | 313 |
| Cow | OR8K1B | 85% | 313 |
| Orang | OR5G1 | 54% | 302 |
| Horse | OR8K1C | 85% | 317 |
| Chimp | OR8K3 | 69% | 308 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC146844 |
Sequence information
| Nucleotide sequence |
ATGAATCATGTGGTAAAACACAATCACACGGCAGTGACCAAGGTGACTGAATTTATTCTC ATGGGGATTACAGACAACCCTGGGCTGCAGGCTCCACTGTTTGGACTCTTCCTCATCATA TATCTGGTCACAGTGATAGGCAATCTGGGCATGGTTATCTTGACCTACTTGGACTCCAAG CTACACACCCCCATGTACTTTTTCCTTAGACATTTGTCAATCACTGATCTTGGTTACTCC ACTGTCATTGCCCCGAAGATGTTAGTAAACTTCATAGTGCACAAAAACACAATTTCTTAC AATTGGTATGCCACTCAGCTAGCATTCTTTGAGATTTTCATCATCTCTGAGCTCTTTATT CTATCAGCAATGGCCTATGATCGCTACGTAGCCATCTGTAAACCTCTTCTGTACGTGATC ATCATGGCAGAGAAAGTACTTTGGGTGCTGGTAATTGTTCCCTATCTCTATAGCACGTTT GTGTCACTATTTCTCACAATTAAGTTATTTAAACTGTCCTTCTGTGGCTCAAACATAATC AGCTATTTTTACTGTGACTGTATCCCTCTGATGTCCATACTCTGTTCTGACACAAATGAA TTAGAATTAATAATTTTGATCTTCTCAGGCTGTAATTTGCTCTTCTCCCTCTCAATTGTT CTCATATCCTACATGTTTATTCTAGTGGCCATTCTCAGAATGAACTCAAGGAAAGGGAGG TACAAAGCCTTCTCCACCTGTAGCTCTCATCTGACAGTGGTGATCATGTTCTATGGGACA TTGTTATTTATTTACTTGCAACCCAAGTCCAGTCATACTTTGGCTATTGATAAAATGGCC TCAGTGTTTTATACCCTGTTGATTCCTATGCTGAATCCGTTGATCTACAGCCTAAGGAAC AAAGAAGTAAAAGATGCTCTAAAGAGAACTTTAACCAATCGATTCAAAATTCCCATT |
| Conceptual translation |
MNHVVKHNHTAVTKVTEFILMGITDNPGLQAPLFGLFLIIYLVTVIGNLGMVILTYLDSK LHTPMYFFLRHLSITDLGYSTVIAPKMLVNFIVHKNTISYNWYATQLAFFEIFIISELFI LSAMAYDRYVAICKPLLYVIIMAEKVLWVLVIVPYLYSTFVSLFLTIKLFKLSFCGSNII SYFYCDCIPLMSILCSDTNELELIILIFSGCNLLFSLSIVLISYMFILVAILRMNSRKGR YKAFSTCSSHLTVVIMFYGTLLFIYLQPKSSHTLAIDKMASVFYTLLIPMLNPLIYSLRN KEVKDALKRTLTNRFKIPI Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | T/C | M/T | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | G/A | P/P | 1000GP (YRI) |
| 11 | 56,113,516 | 56,113,516 | NS | T/C | M/T | rs1905055 (DbSNP) |
| 11 | 56,113,575 | 56,113,575 | NS | A/G | M/V | rs10896271 (DbSNP) |
| 11 | 56,113,593 | 56,113,593 | NS | A/C | T/P | rs10896272 (DbSNP) |
| 11 | 56,113,764 | 56,113,764 | NS | A/G | T/A | rs17614327 (DbSNP) |
| 11 | 56,113,769 | 56,113,769 | SYN | A/G | P/P | rs17150344 (DbSNP) |
| 11 | 56,113,923 | 56,113,923 | SYN | C/T | L/L | rs61745885 (DbSNP) |
| 11 | 56,346,040 | 56,346,040 | NS | T/C | M/T | 1000GP (CEU, CHBJPT) |
| 11 | 56,346,099 | 56,346,099 | NS | A/G | M/V | 1000GP (CEU, CHBJPT) |
| 11 | 56,346,117 | 56,346,117 | NS | C/A | P/T | 1000GP (CEU, CHBJPT) |
| 11 | 56,346,172 | 56,346,172 | NS | T/G | V/G | 1000GP (CHBJPT) |
| 11 | 56,346,288 | 56,346,288 | NS | G/A | A/T | 1000GP (CEU) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| M1T | M21V | P27T | V45G | A84T | L217F | I219T | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | T | V | T | V | A | L | I | 40.09 | 1.200 |
| 2 | T | M | P | V | A | L | I | 26.65 | 1.200 |
| 3 | M | M | P | V | A | L | I | 24.35 | 0.917 |
| 4 | T | M | P | V | T | L | I | 4.99 | 1.200 |
| 5 | T | V | P | V | A | L | I | 1.15 | 1.200 |
| 6 | T | V | T | G | A | L | I | 0.61 | 1.200 |
| 7 | T | M | P | V | A | F | I | 0.61 | 1.200 |
| 8 | T | M | T | V | A | L | I | 0.54 | 2.000 |
| 9 | T | M | P | V | A | L | T | 0.38 | 1.200 |
| 10 | M | M | T | V | A | L | I | 0.23 | 0.917 |
| 11 | M | M | P | V | T | L | I | 0.23 | 0.917 |
| 12 | M | V | T | V | A | L | I | 0.08 | 0.917 |
| 13 | T | V | P | V | T | L | I | 0.08 | 1.200 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR8K1.aApr07-unspliced | main_exon | CDS | chr11 | 56,346,039 | 56,346,995 | + |
| 3UTR | chr11 | 56,346,995 | 56,346,998 | + | ||