OR10A3 Olfactory Receptor
| Gene Symbol | OR10A31 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | HSHTPCRX12, OR11-97, HsOR11.5.8, ORL45 |
| External Ids | HGNC: 8162 GeneBank: AB065768, AB065940, AF399634, AY284325-AY284356, BK004404, HSHTPRX12, NM_001003745 ORDB: ORL45 |
| Build #39 labels | OR10A3 |
| Chromosomal location | 11:7,938,579-7,939,520 (-) |
| Cluster | 11@8 |
| Synteny | CLIC#25 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10A6 | 85.3% | 313 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10A3E | 87% | 314 |
| Dog | OR10A6 | 84% | 314 |
| Mouse | Or10a3 | 83% | 311 |
| Mouse | Or10a3b | 81% | 313 |
| Rat | Or10a3 | 83% | 312 |
| Rat | Or10a3d | 81% | 313 |
| Cow | OR10A3F | 89% | 314 |
| Cow | OR10A3HP | 87% | 314 |
| Orang | OR10A3K | 94% | 313 |
| Orang | OR10A3J | 92% | 313 |
| Horse | OR10A3L | 90% | 314 |
| Chimp | OR10A3P | 97% | 313 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | FN165431 |
| mRNA | AB529269 |
| GNF Atlas2 | gnf1h05415_at |
| GNF Atlas2 | gnf1h05416_s_at |
Sequence information
| Nucleotide sequence |
ATGAAAAGACAAAATCAAAGCTGTGTGGTTGAATTCATCCTCCTGGGCTTTTCTAACTTT CCTGAGCTCCAGGTGCAGCTCTTTGGGGTTTTCCTAGTTATTTATGTGGTGACCCTGATG GGAAATGCCATCATTACAGTCATCATCTCCTTAAACCAGAGCCTCCACGTTCCCATGTAC CTGTTCCTCCTGAACCTATCTGTGGTGGAGGTGAGTTTCAGTGCAGTCATTACGCCTGAA ATGCTGGTGGTGCTCTCTACTGAGAAAACTATGATTTCTTTTGTGGGCTGTTTTGCACAG ATGTATTTCATCCTTCTTTTTGGTGGGACTGAATGTTTTCTCCTGGGAGCGATGGCTTAT GACCGATTTGCTGCAATTTGCCATCCTCTGAACTACCCAGTGATTATGAACAGAGGGGTT TTTATGAAATTAGTAATATTCTCATGGATCTCAGGGATCATGGTGGCTACTGTGCAGACC ACTTGGGTATTTAGTTTTCCATTTTGTGGCCCCAATGAAATTAATCATCTCTTCTGTGAG ACTCCCCCGGTACTAGAGCTTGTGTGTGCAGACACCTTCTTATTTGAAATCTATGCCTTC ACAGGCACCATTTTGATTGTTATGGTTCCTTTCTTGTTGATCCTCTTGTCTTACATTCGA GTTCTGTTTGCCATCCTGAAGATGCCATCAACTACTGGGAGACAAAAGGCCTTTTCCACC TGTGCCTCTCACCTCACATCTGTGACCCTGTTCTATGGCACAGCCAATATGACTTATTTA CAACCCAAATCTGGCTACTCACCCGAAACCAAGAAACTGATCTCATTGGCTTACACGTTG CTTACCCCTCTGCTCAATCCGCTCATCTATAGCTTACGAAACAGTGAGATGAAGAGGACT TTGATAAAACTATGGCGAAGAAAAGTGATTTTACACACATTC |
| Conceptual translation |
MKRQNQSCVVEFILLGFSNFPELQVQLFGVFLVIYVVTLMGNAIITVIISLNQSLHVPMY LFLLNLSVVEVSFSAVITPEMLVVLSTEKTMISFVGCFAQMYFILLFGGTECFLLGAMAY DRFAAICHPLNYPVIMNRGVFMKLVIFSWISGIMVATVQTTWVFSFPFCGPNEINHLFCE TPPVLELVCADTFLFEIYAFTGTILIVMVPFLLILLSYIRVLFAILKMPSTTGRQKAFST CASHLTSVTLFYGTANMTYLQPKSGYSPETKKLISLAYTLLTPLLNPLIYSLRNSEMKRT LIKLWRRKVILHTF Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | T/C | N/S | 1000GP (YRI, YRI, YRI, YRI) |
| 11 | 7,960,751 | 7,960,751 | Del(1) | -/A | rs35194212 (DbSNP) | |
| 11 | 7,961,006 | 7,961,006 | NS | G/T | P/H | rs11606157 (DbSNP) |
| 11 | 7,961,010 | 7,961,010 | NS | A/C | F/V | rs16934214 (DbSNP) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| N172S | V163I | Q159E | Y132H | F20V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | N | V | Q | Y | F | 97.24 | 0.098 |
| 2 | N | V | Q | Y | V | 1.38 | 0.098 |
| 3 | S | V | Q | Y | F | 0.92 | 0.098 |
| 4 | N | V | E | Y | F | 0.23 | 0.098 |
| 5 | N | I | Q | Y | F | 0.15 | 0.098 |
| 6 | N | V | Q | H | F | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10A3.aApr07-unspliced | main_exon | 3UTR | chr11 | 7,938,576 | 7,938,579 | - |
| CDS | chr11 | 7,938,579 | 7,939,520 | - | ||