OR10A4 Olfactory Receptor
| Gene Symbol | OR10A41 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.03 (functional) |
| Aliases | OR11-78, OR11-87, JCG5, HsOR11.4.6, ORL356 |
| External Ids | HGNC: 15130 GeneBank: AF209506, AF399625, BK004201, BK004564, NM_207186 ORDB: ORL356 |
| Build #39 labels | OR10A4P |
| Chromosomal location | 11:6,876,621-6,877,592 (+) |
| Cluster | 11@7 |
| Synteny | CLIC#24 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10A5 | 75.49% | 306 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10A5F | 74% | 311 |
| Mouse | Or10a4 | 88% | 317 |
| Rat | Or10a4 | 87% | 315 |
| Cow | OR10A5 | 73% | 311 |
| Orang | OR10A5 | 74% | 311 |
| Horse | OR10A5 | 73% | 311 |
| Chimp | OR10A5 | 75% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AF209506 |
| GNF Atlas2 | gnf1h08194_at |
Sequence information
| Nucleotide sequence |
ATGCCCAGTGAAGTCCTGGGCAGAAGAATGATGTGGGAAAACTGGACAATTGTCAGTGAA TTTGTTCTCGTGAGCTTCTCAGCCCTGTCCACTGAGCTTCAGGCTCTACTGTTTCTCCTT TTCTTGACCATTTACTTGGTTACTTTAATGGGCAATGTCCTCATCATCCTGGTCACTATA GCTGACTCTGCACTACAAAGTCCTATGTACTTCTTCCTCAGAAACTTGTCCTTCCTGGAG ATAGGTTTCAACTTGGTCATTGTGCCCAAGATGCTGGGGACCCTGATCATTCAAGACACA ACCATCTCCTTCCTTGGATGTGCCACTCAGATGTATTTCTTCTTCTTTTTTGGGGCTGCT GAGTGCTGCCTCCTGGCCACCATGGCATATGACCGCTACGTGGCCATCTGTGACCCCTTG CACTACCCAGTCATCATGGGCCACATATCCTGTGCCCAGCTGGCAGCTGCCTCTTGGTTC TCAGGGTTTTCAGTGGCCACTGTGCAAACCACATGGATTTTCAGTTTCCCTTTTTGTGGC CCCAACAGGGTGAACCACTTCTTCTGTGACAGCCCTCCTGTTATTGCACTGGTCTGTGCT GACACCTCTGTGTTTGAACTGGAGGCTCTGACAGCCACTGTCCTATTCATTCTCTTTCCT TTCTTGCTGATCCTGGGATCCTATGTCCGCATCCTCTCCACTATCTTCAGGATGCCGTCA GCTGAGGGGAAACATCAGGCATTCTCCACCTGTTCCGCCCACCTCTTGGTTGTCTCTCTC TTCTATAGCACTGCCATCCTCACGTATTTCCGACCCCAATCCAGTGCCTCTTCTGAGAGC AAGAAGCTGCTGTCACTCTCTTCCACAGTGGTGACTCCCATGTTGAACCCCATCATCTAC AGCTCAAGGAATAAAGAAGTGAAGGCTGCACTGAAGCGGCTTATCCACAGGACCCTGGGC TCTCAGAAACTA |
| Conceptual translation |
MPSEVLGRRMMWENWTIVSEFVLVSFSALSTELQALLFLLFLTIYLVTLMGNVLIILVTI ADSALQSPMYFFLRNLSFLEIGFNLVIVPKMLGTLIIQDTTISFLGCATQMYFFFFFGAA ECCLLATMAYDRYVAICDPLHYPVIMGHISCAQLAAASWFSGFSVATVQTTWIFSFPFCG PNRVNHFFCDSPPVIALVCADTSVFELEALTATVLFILFPFLLILGSYVRILSTIFRMPS AEGKHQAFSTCSAHLLVVSLFYSTAILTYFRPQSSASSESKKLLSLSSTVVTPMLNPIIY SSRNKEVKAALKRLIHRTLGSQKL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | T/C | W/R | 1000GP (YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | A/C | R/R | 1000GP (YRI) |
| 11 | 6,877,251 | 6,877,251 | NS | A/C | T/P | 1000GP (CHBJPT) |
| 11 | 6,877,264 | 6,877,264 | NS | T/C | L/P | 1000GP (CEU) |
| 11 | 6,877,432 | 6,877,432 | NS | G/A | R/Q | 1000GP (CEU, CHBJPT) |
| 11 | 6,877,527 | 6,877,527 | SYN | A/C | R/R | 1000GP (CEU, CHBJPT) |
| 11 | 6,898,495 | 6,898,495 | NS | C/T | P/L | rs2595453 (DbSNP) |
| 11 | 6,898,540 | 6,898,540 | NS | A/G | H/R | rs7938371 (DbSNP) |
| 11 | 6,898,614 | 6,898,614 | NS | C/T | L/F | rs16919049 (DbSNP) |
| 11 | 6,898,663 | 6,898,663 | NS | A/G | Q/R | rs10839635 (DbSNP) |
| 11 | 6,898,758 | 6,898,758 | SYN | A/C | R/R | rs7102808 (DbSNP) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| W163R | L206P | R221H | Q237K | L246F | R262Q | S279Y | R304Q | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | W | L | R | Q | L | R | S | R | 57.45 | 0.022 |
| 2 | W | L | R | Q | L | Q | S | R | 27.73 | 0.022 |
| 3 | W | L | H | Q | L | R | S | R | 7.76 | 0.022 |
| 4 | W | L | H | Q | F | R | S | R | 3.15 | 0.022 |
| 5 | W | P | R | Q | L | R | S | R | 2.46 | 0.022 |
| 6 | R | L | R | Q | L | R | S | R | 0.46 | 0.022 |
| 7 | W | L | R | K | L | R | Y | R | 0.46 | 0.022 |
| 8 | W | L | R | Q | L | Q | S | Q | 0.31 | 0.022 |
| 9 | W | P | H | Q | L | R | S | R | 0.15 | 0.022 |
| 10 | W | P | R | Q | L | Q | S | R | 0.08 | 0.022 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10A4.aApr07-unspliced | main_exon | CDS_partial | chr11 | 6,876,648 | 6,877,592 | + |
| 3UTR | chr11 | 6,877,592 | 6,877,595 | + | ||