OR10A7 Olfactory Receptor
| Gene Symbol | OR10A71 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OR12-6, HsOR12.5.5, ORL3655 |
| External Ids | HGNC: 15329 GeneBank: AB065864, AF399626, BK004327, NM_001005280 ORDB: ORL3655 |
| Build #39 labels | OR10A7 |
| Chromosomal location | 12:55,221,025-55,221,972 (+) |
| Cluster | 12@56 |
| Synteny | CLIC#31 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10A2 | 61.22% | 294 |
| OR10A4 | 61.76% | 306 |
| OR10A5 | 61.41% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10A5 | 62% | 310 |
| Mouse | Or10a4 | 63% | 315 |
| Rat | Or10a4 | 63% | 316 |
| Cow | OR10A5 | 61% | 306 |
| Orang | OR10A4 | 62% | 315 |
| Horse | OR10A56P | 78% | 306 |
| Chimp | OR10A5 | 62% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB529271 |
| GNF Atlas2 | gnf1h10668_at |
Sequence information
| Nucleotide sequence |
ATGATCTGTGAAAATCACACCAGAGTCACTGAATTTATTCTTCTTGGTTTTACAAACAAC CCCGAGATGCAAGTTTCCCTCTTTATTTTTTTCCTGGCCATTTATACAGTCACTTTGTTG GGCAACTTTCTTATTGTCACAGTTACCAGTGTGGATCTCGCACTTCAAACACCCATGTAC TTCTTTCTTCAAAATCTGTCACTTCTTGAAGTATGTTTCACCTTGGTTATGGTGCCAAAA ATGCTTGTAGATCTAGTGTCCCCAAGGAAAATTATCTCTTTTGTGGGCTGTGGTACCCAG ATGTACTTCTTCTTCTTCTTTGGCAGTTCTGAATGTTTCCTTCTCTCCATGATGGCTTAT GATCGCTTTGTGGCCATCTGTAACCCTCTCCATTATTCAGTCATAATGAACAGGTCCCTA TGCTTGTGGATGGCCATAGGCTCTTGGATGTCCGGTGTTCCTGTGTCTATGCTACAGACA GCTTGGATGATGGCCCTTCCTTTCTGTGGACCAAATGCCGTGGACCACTTTTTCTGTGAT GGTCCCCCAGTGTTAAAACTAGTCACAGTGGATACAACCATGTATGAAATGCAAGCACTT GCCTCCACACTCCTGTTTATCATGTTTCCCTTTTGTCTCATTTTGGTTTCCTACACCCGC ATTATCATAACAATTCTGAGGATGTCCTCTGCCACTGGCCGCCAGAAGGCATTTTCTACT TGTTCCTCACACCTCATTGTGGTGTCCCTCTTCTACGGAACAGCCAGTCTGACCTACCTG CGGCCCAAATCAAACCAGTCCCCTGAGAGCAAGAAGCTAGTGTCATTGTCCTACACTGTC ATCACACCTATGCTAAACCCCATCATCTACGGCCTGAGGAACAATGAAGTGAAAGGGGCT GTCAAGAGGACAATCACTCAAAAAGTCTTACAGAAGTTAGATGTGTTT |
| Conceptual translation |
MICENHTRVTEFILLGFTNNPEMQVSLFIFFLAIYTVTLLGNFLIVTVTSVDLALQTPMY FFLQNLSLLEVCFTLVMVPKMLVDLVSPRKIISFVGCGTQMYFFFFFGSSECFLLSMMAY DRFVAICNPLHYSVIMNRSLCLWMAIGSWMSGVPVSMLQTAWMMALPFCGPNAVDHFFCD GPPVLKLVTVDTTMYEMQALASTLLFIMFPFCLILVSYTRIIITILRMSSATGRQKAFST CSSHLIVVSLFYGTASLTYLRPKSNQSPESKKLVSLSYTVITPMLNPIIYGLRNNEVKGA VKRTITQKVLQKLDVF Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 12 | 100 | -100 | NS | T/C | L/P | 1000GP (YRI, YRI) |
| 12 | 55,221,310 | 55,221,310 | NS | G/A | G/S | 1000GP (CHBJPT) |
| 12 | 55,221,543 | 55,221,543 | SYN | C/T | A/A | 1000GP (CEU) |
| 12 | 55,615,094 | 55,615,094 | NS | A/G | S/G | rs12578318 (DbSNP) |
| 12 | 55,615,703 | 55,615,702 | Ins(1) | -/G | rs34372866 (DbSNP) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| S50N | D52E | L53P | L66V | G96S | F106L | C141R | K272Q | G291S | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | S | D | L | L | G | F | C | K | G | 97.54 | 0.081 |
| 2 | S | D | L | L | S | F | C | K | G | 1.00 | 0.081 |
| 3 | S | D | L | L | G | F | R | K | G | 0.54 | 0.081 |
| 4 | S | D | P | V | G | L | C | K | S | 0.46 | 0.418 |
| 5 | N | D | L | L | G | F | C | K | G | 0.15 | 0.081 |
| 6 | S | E | L | L | G | F | C | K | G | 0.15 | 0.081 |
| 7 | S | D | L | L | G | F | C | Q | G | 0.08 | 0.081 |
| 8 | S | D | P | L | G | L | C | K | S | 0.08 | 0.081 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10A7.aApr07-unspliced | main_exon | CDS | chr12 | 55,221,025 | 55,221,972 | + |
| 3UTR | chr12 | 55,221,972 | 55,221,975 | + | ||