OR10AG1 Olfactory Receptor

Gene Symbol	OR10AG1¹ (View this gene in GeneCards)
Family	10
Subfamily	AG
Pseudogene	No
CORP pseudogene probability score	0.03 (functional)
Aliases	OR11-160, HsOR11.11.37
External Ids	HGNC: 19607 GeneBank: AB065594, BK004519, NM_001005491
Build #39 labels	OR10AG1
Chromosomal location	11:55,967,561-55,968,463 (-)
Cluster	11@56
Synteny	CLIC#26
Remarks

Most Similar ORs in Humans (Paralogs)

Symbol	Percent	Length
OR10A7	47.81%	297
OR10C1	48.15%	297
OR10R3P	46.8%	297

Most Similar ORs in other species (Orthologs)

Specie	Symbol	Percent	Length
Dog	OR10AG64	68%	295
Mouse	Or10ag2	75%	300
Rat	Or10ag2	74%	300
Cow	OR10AG65	66%	301
Orang	OR10A5	49%	300
Horse	OR10AG104P	77%	296
Chimp	OR10AG1P	97%	290

Expression evidences

Source	Accession
mRNA	AB529272
GNF Atlas2	gnf1h05460_at

Sequence information

Nucleotide sequence

ATGGAATTTGTTCTTTTGGGGTTTTCTGATATTCCCAATCTCCACTGGATGCTTTTTAGT
ATATTTTTACTTATGTATTTGATGATCCTGATGTGCAATGGCATCATAATACTACTAATA
AAAATTCACCCCGCTCTCCAGACTCCCATGTATTTTTTTCTTAGCAATTTTTCCCTTTTG
GAAATCTGTTATGTAACAATCATTATCCCAAGAATGCTCATGGACATTTGGACTCAGAAA
GGAAATATTTCTTTGTTTGCTTGTGCTACACAAATGTGTTTTTTTCTTATGCTTGGAGGC
ACGGAGTGTCTCCTTCTGACAGTGATGGCCTATGACCGCTACGTGGCTATTTGTAAGCCT
TTGCAGTATCCTCTAGTGATGAACCACAAAGTCTGCATTCAGCTGATAATAGCTTCCTGG
ACCATCACAATTCCTGTAGTAATTGGGGAAACATGCCAAATTTTCCTTTTGCCCTTTTGC
GGAACTAACACAATTAATCATTTCTTTTGTGACATCCCGCCAATACTCAAGCTTGCTTGT
GGAAACATATTTGTGAATGAGATAACAGTCCATGTAGTAGCGGTGGTGTTTATCACGGTG
CCATTTCTGTTGATTGTTGTCTCTTATGGCAAAATTATCTCCAACATTTTGAAATTGTCA
TCAGCCAGAGGAAAGGCTAAAGCCTTCTCCACCTGCTCATCTCACCTAATAGTTGTAATC
TTATTCTTTGGAGCAGGTACTATCACTTATTTACAGCCCAAACCACATCAGTTTCAAAGG
ATGGGGAAACTGATTTCTCTTTTCTACACCATTCTGATTCCAACTTTGAATCCTATTATA
TATACCCTGAGGAACAAAGATATCATGGTGGCATTGAGAAAATTACTAGCTAAGTTATTA
ACA

Conceptual translation

MEFVLLGFSDIPNLHWMLFSIFLLMYLMILMCNGIIILLIKIHPALQTPMYFFLSNFSLL
EICYVTIIIPRMLMDIWTQKGNISLFACATQMCFFLMLGGTECLLLTVMAYDRYVAICKP
LQYPLVMNHKVCIQLIIASWTITIPVVIGETCQIFLLPFCGTNTINHFFCDIPPILKLAC
GNIFVNEITVHVVAVVFITVPFLLIVVSYGKIISNILKLSSARGKAKAFSTCSSHLIVVI
LFFGAGTITYLQPKPHQFQRMGKLISLFYTILIPTLNPIIYTLRNKDIMVALRKLLAKLL
T

Protein domains and features

Variations - SNPs

Chr	Start	End	Type	Variation	AA Change	SNP IDs
11	55,735,649	55,735,649	NS	A/C	I/M	rs61896167 (DbSNP)
11	55,735,518	55,735,518	NS	A/G	I/T	rs61896165 (DbSNP)
11	55,735,579	55,735,579	SYN	A/G	L/L	rs61896166 (DbSNP)
11	55,735,106	55,735,106	SYN	A/G	P/P	rs61896163 (DbSNP)
11	55,735,280	55,735,280	SYN	A/T	S/S	rs61896164 (DbSNP)
11	55,735,091	55,735,091	SYN	C/T	L/L	rs12292026 (DbSNP)
11	55,968,337	55,968,337	NS	G/C	H/D	1000GP (CEU)
11	55,967,797	55,967,797	NS	T/C	R/G	1000GP (CEU)
11	55,968,173	55,968,173	NS	C/A	M/I	1000GP (CEU)
11	55,968,042	55,968,042	NS	G/A	T/I	1000GP (CEU)
11	55,968,103	55,968,103	SYN	A/G	L/L	1000GP (CEU)
11	55,967,937	55,967,937	NS	A/G	L/P	1000GP (CEU)
11	55,967,630	55,967,630	SYN	A/G	P/P	1000GP (CEU)
11	55,968,332	55,968,332	SYN	G/A	P/P	1000GP (CEU)
11	55,967,804	55,967,804	SYN	T/A	S/S	1000GP (CEU)
11	55,968,372	55,968,372	NS	A/G	M/T	1000GP (CEU)
11	55,968,381	55,968,381	NS	A/G	M/T	1000GP (CEU)
11	55,967,872	55,967,872	NS	T/A	I/F	1000GP (CHBJPT)
11	100	-100	SYN	C/T	L/L	1000GP (YRI, YRI, YRI)
11	100	-100	NS	G/A	T/I	1000GP (YRI, YRI, YRI)

Variations - CNVs

Chr	Start	End	Type	Sources
11	55,153,930	55,816,828	CopyNumber	Variation_0308 (DGV)
11	55,710,709	55,787,839	CopyNumber	Variation_1245 (DGV)
11	55,689,863	55,849,156	CopyNumber	Variation_2927 (DGV)
11	54,835,623	55,879,426	CopyNumber	Variation_8690 (DGV)
11	55,685,799	55,842,512	CopyNumber	Variation_9189 (DGV)
11	55,685,556	55,819,544	CopyNumber	Variation_29912 (DGV), Variation_48846 (DGV)
11	55,685,556	55,796,170	CopyNumber	Variation_48845 (DGV)
11	55,685,556	55,836,620	CopyNumber	Variation_48847 (DGV)
11	55,683,109	55,833,490	CopyNumber	Variation_85786 (DGV)

Haplotypes

Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.

	V239A	V192I	L176P	T141I	M97I	H43D	M31T	M28T	% Freq	CORP
1	V	V	L	T	M	H	M	M	94.09	0.078
2	V	V	L	I	I	D	T	T	3.92	0.078
3	A	V	L	T	M	H	M	M	0.54	0.135
4	V	V	L	I	I	H	M	M	0.54	0.078
5	V	I	L	T	M	H	M	M	0.46	0.078
6	V	V	L	I	I	H	T	T	0.15	0.078
7	V	V	P	I	I	D	M	T	0.08	0.078
8	V	V	L	I	I	D	M	M	0.08	0.078
9	V	V	L	T	I	D	T	T	0.08	0.078
10	V	V	L	T	M	D	T	T	0.08	0.078

AceView Gene Models

The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.

Accession	Type		Chr	Start	End	Strand
OR10AG1.aApr07-unspliced	main_exon	3UTR	chr11	55,967,558	55,967,561	-
OR10AG1.aApr07-unspliced	main_exon	CDS	chr11	55,967,561	55,968,463	-

HORDE

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