OR10G2 Olfactory Receptor

Gene Symbol	OR10G2¹ (View this gene in GeneCards)
Family	10
Subfamily	G
Pseudogene	No
CORP pseudogene probability score	0.23 (functional)
Aliases	OR14-41, AE000658-B, HsOR14.2.4, ORL3697
External Ids	HGNC: 8170 GeneBank: AB065894, BK004670, NM_001005466 ORDB: ORL3697
Build #39 labels	OR10G2
Chromosomal location	14:21,633,913-21,634,842 (-)
Cluster	14@22b
Synteny	CLIC#35
Remarks

Most Similar ORs in Humans (Paralogs)

Symbol	Percent	Length
OR10G1P	93.87%	310

Most Similar ORs in other species (Orthologs)

Specie	Symbol	Percent	Length
Dog	OR10G6	62%	295
Mouse	Or10g1	90%	310
Mouse	Or10g1b	88%	310
Rat	Or10g1	88%	310
Rat	Or10g1b	87%	310
Cow	OR10G1	91%	310
Cow	OR10G1C	89%	310
Orang	OR10G1P	91%	310
Orang	OR10G1E	91%	310
Orang	OR10G1D	91%	310
Horse	OR10G1	92%	310
Horse	OR10G1G	89%	310
Chimp	OR10G1	96%	310
Chimp	OR10G1C	95%	310

Expression evidences

Source	Accession
mRNA	AB529274
GNF Atlas2	gnf1h11245_at

Sequence information

Nucleotide sequence

ATGGGAAAGACCAAAAACACATCGCTGGATGCCGTGGTGACAGATTTCATTCTTCTGGGT
TTGTCTCACCCCCCAAATCTAAGAAGCCTCCTCTTCCTGGTCTTCTTCATCATTTACATC
CTCACTCAGCTGGGGAACCTGCTCATTCTGCTCACCATGTGGGCTGACCCGAAGCTCTGT
GCTCGCCCCATGTACATTCTTCTGGGAGTGCTCTCATTCCTGGACATGTGGCTCTCCTCA
GTCACCGTTCCTCGGCTTATTTTGGATTTTACTCCTTCCATCAAGGCTATCCCGTTTGGT
GGCTGTGTGGCTCAACTGTATTTCTTTCACTTCCTGGGCAGCACCCAGTGCTTCCTCTAC
ACCTTGATGGCCTATGACAGGTACCTAGCAATATGTCAGCCCCTGCACTACCCAGTGCTC
ATGAATGGGAGGTTATGCACAGTCCTTGTGGCTGGAGCTTGGGTCGCCGGCTCCATGCAT
GGGTCTATCCAGGCCACCTTGACCTTCCGCCTGCCCTACTGTGGGCCCAATCAGGTGGAT
TACTTTATCTGTGACATCCGCGCAGTATTGAGACTGGCCTGTGCTGACACAACTGTCAAT
GAGCTTGTGACCTTTGTGGACGTCAGGGTAGTGGCCGCCAGTTGCTTCATGTTAATTCTG
CTCTCCTATGCCAACATAGTCCATGCCATCCTGAAGATACGCACCGCTGATGGGAGGCGC
CGGGCCTTCTCCACCTGTGGCTCCCACCTAATCGTGGTCACAGTCTACTATGTCCCCTGT
ATTTTCATCTACCTTAGGGCTGGCTCCAAAGACCCCCTGGATGGGGCAGCGGCTGTGTTT
TACACTGTTGTCACTCCATTACTGAACCCCCTCATCTATACACTGAGGAACCAGGAAGTG
AAGTCTGCCCTGAAGAGGATAACAGCAGGT

Conceptual translation

MGKTKNTSLDAVVTDFILLGLSHPPNLRSLLFLVFFIIYILTQLGNLLILLTMWADPKLC
ARPMYILLGVLSFLDMWLSSVTVPRLILDFTPSIKAIPFGGCVAQLYFFHFLGSTQCFLY
TLMAYDRYLAICQPLHYPVLMNGRLCTVLVAGAWVAGSMHGSIQATLTFRLPYCGPNQVD
YFICDIRAVLRLACADTTVNELVTFVDVRVVAASCFMLILLSYANIVHAILKIRTADGRR
RAFSTCGSHLIVVTVYYVPCIFIYLRAGSKDPLDGAAAVFYTVVTPLLNPLIYTLRNQEV
KSALKRITAG

Protein domains and features

Variations - SNPs

Chr	Start	End	Type	Variation	AA Change	SNP IDs
14	100	-100	NS	C/G	R/P	1000GP (YRI, YRI, YRI)
14	100	-100	SYN	A/G	H/H	1000GP (YRI, YRI)
14	21,634,137	21,634,137	NS	C/T	A/T	1000GP (CEU)
14	21,634,161	21,634,161	NS	G/T	H/N	1000GP (CEU)
14	21,634,162	21,634,162	SYN	G/T	V/V	1000GP (CEU)
14	21,634,177	21,634,177	SYN	G/C	S/S	1000GP (CEU)
14	21,634,283	21,634,283	NS	C/G	R/P	1000GP (CEU)
14	21,634,436	21,634,436	NS	T/C	H/R	1000GP (CEU, CHBJPT)
14	21,634,456	21,634,456	SYN	T/C	L/L	1000GP (CEU, CHBJPT)
14	21,634,589	21,634,589	NS	C/A	R/L	1000GP (CEU, CHBJPT)
14	22,102,169	22,102,169	NS	A/G	V/A	rs28445447 (DbSNP)
14	22,102,293	22,102,293	NS	C/T	A/T	rs41307110 (DbSNP)
14	22,102,315	22,102,315	SYN	G/A	H/H	rs61753931 (DbSNP)
14	22,102,333	22,102,333	SYN	C/G	S/S	rs41317324 (DbSNP)
14	22,102,374	22,102,374	NS	C/T	G/R	rs12894405 (DbSNP)
14	22,102,414	22,102,414	SYN	A/T	A/A	rs10136017 (DbSNP)
14	22,102,439	22,102,439	NS	C/G	R/P	rs35963889 (DbSNP)
14	22,102,592	22,102,592	NS	C/T	R/H	rs10138694 (DbSNP)
14	22,102,612	22,102,612	SYN	C/T	L/L	rs10138704 (DbSNP)
14	22,102,745	22,102,745	NS	A/C	L/R	rs41314525 (DbSNP)
14	22,102,800	22,102,800	NS	A/G	F/L	rs10146821 (DbSNP)
14	22,102,829	22,102,829	NS	A/G	L/P	rs57476477 (DbSNP)
14	22,102,871	22,102,871	NS	T/C	Q/R	rs61754893 (DbSNP)

Variations - CNVs

Chr	Start	End	Type	Sources
14	21,931,624	22,169,502	CopyNumber	Variation_5318 (DGV)

Haplotypes

Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.

	A236T	R209G	R187P	H136R	P98L	R85L	L67F	P57L	M53V	Q43R	K5N	% Freq	CORP
1	A	R	R	H	P	R	L	P	M	Q	K	53.99	0.139
2	A	G	P	R	P	L	L	P	M	Q	K	6.84	0.139
3	A	G	P	H	P	R	L	P	M	Q	K	5.84	0.139
4	A	G	P	H	P	L	L	P	M	Q	K	5.30	0.139
5	A	G	P	R	P	R	L	P	M	Q	K	4.84	0.139
6	A	G	R	R	P	R	F	P	M	Q	K	4.07	0.139
7	A	G	R	H	P	R	F	P	M	Q	K	3.00	0.139
8	A	R	R	H	P	L	L	P	M	Q	K	2.38	0.139
9	T	G	P	R	P	L	L	P	M	Q	K	2.15	0.139
10	T	G	P	H	P	L	L	P	M	Q	K	2.00	0.139
11	A	G	R	R	P	R	L	P	M	Q	K	1.23	0.139
12	A	G	R	H	P	R	L	P	M	Q	K	1.15	0.139
13	A	R	P	H	P	L	L	P	M	Q	K	1.00	0.139
14	A	R	R	R	P	L	L	P	M	Q	K	1.00	0.139
15	A	R	R	H	P	R	F	P	M	Q	K	0.84	0.139
16	A	R	R	H	P	R	L	P	M	R	K	0.69	0.139
17	A	G	R	R	P	L	L	P	M	Q	K	0.54	0.139
18	T	R	R	H	P	L	L	P	M	Q	K	0.46	0.139
19	A	G	R	H	P	L	L	P	M	Q	K	0.38	0.139
20	A	G	P	R	P	L	L	P	V	Q	K	0.31	0.139
21	A	R	P	H	P	R	L	P	M	Q	K	0.23	0.139
22	T	R	P	H	P	L	L	P	M	Q	K	0.23	0.139
23	A	G	P	R	P	R	L	L	M	Q	K	0.23	0.139
24	T	G	P	R	P	R	L	P	M	Q	K	0.15	0.139
25	A	G	P	H	P	L	L	P	V	Q	K	0.15	0.139
26	T	R	R	R	P	L	L	P	M	Q	K	0.15	0.139
27	A	R	R	R	P	R	F	P	M	Q	K	0.15	0.139
28	A	R	R	R	P	R	L	L	M	Q	K	0.08	0.139
29	A	R	P	R	P	L	L	P	M	Q	K	0.08	0.139
30	A	R	P	H	P	R	F	P	M	Q	K	0.08	0.139
31	T	G	R	R	P	L	L	P	M	Q	K	0.08	0.139
32	A	G	P	R	L	R	L	P	M	Q	K	0.08	0.139
33	A	R	R	H	P	R	L	P	M	Q	N	0.08	0.139
34	T	G	R	H	P	L	L	P	M	Q	K	0.08	0.139
35	A	G	R	R	P	L	L	P	V	Q	K	0.08	0.139
36	A	R	R	R	P	R	L	P	M	Q	K	0.08	0.139

AceView Gene Models

The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.

Accession	Type		Chr	Start	End	Strand
OR10G2.aApr07-unspliced	main_exon	3UTR	chr14	21,633,910	21,633,913	-
OR10G2.aApr07-unspliced	main_exon	CDS	chr14	21,633,913	21,634,842	-

HORDE

Search Olfactory receptors

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