OR10G4 Olfactory Receptor

Gene Symbol	OR10G4¹ (View this gene in GeneCards)
Family	10
Subfamily	G
Pseudogene	No
CORP pseudogene probability score	0.05 (functional)
Aliases	OR11-278, HsOR11.18.11, ORL3288
External Ids	HGNC: 14809 GeneBank: AB065757, BK004502, NM_001004462 ORDB: ORL3288
Build #39 labels	OR10G4
Chromosomal location	11:124,015,575-124,016,507 (+)
Cluster	11@124
Synteny	CLIC#29
Remarks

Most Similar ORs in Humans (Paralogs)

Symbol	Percent	Length
OR10G7	91.42%	303
OR10G8	87.14%	311
OR10G9	94.82%	309

Most Similar ORs in other species (Orthologs)

Specie	Symbol	Percent	Length
Dog	OR10G9C	86%	311
Dog	OR10G9	85%	311
Dog	OR10G7BP	84%	304
Mouse	Or10g9	86%	311
Mouse	Or10g9b	85%	310
Mouse	Or10g7	85%	311
Rat	Or10g9	86%	309
Rat	Or10g9b	85%	310
Cow	OR10G9E	82%	311
Cow	OR10G4B	82%	311
Cow	OR10G9D	80%	311
Orang	OR10G9	91%	311
Orang	OR10G9I	88%	311
Horse	OR10G9	86%	307
Horse	OR10G9J	85%	311
Horse	OR10G7	85%	304
Horse	OR10G9K	86%	291
Chimp	OR10G9	93%	311

Expression evidences

Source	Accession
GNF Atlas2	gnf1h05557_at
GNF Atlas2	gnf1h05558_s_at

Sequence information

Nucleotide sequence

ATGTCCAACGCCAGCCTCGTGACAGCATTCATCCTCACAGGCCTTCCCCATGCCCCAGGG
CTGGACGCCCTCCTCTTTGGAATCTTCCTGGTGGTTTACGTGCTCACTGTGCTGGGGAAC
CTCCTCATCCTGCTGGTGATCAGGGTGGATTCTCACCTCCACACCCCCATGTACTACTTC
CTCACCAACCTGTCCTTCATTGACATGTGGTTCTCCACTGTCACGGTGCCCAAAATGCTG
ATGACCTTGGTGTCCCCAAGCGGCAGGGCTATCTCCTTCCACAGCTGCGTGGCTCAGCTC
TATTTTTTCCACTTCCTGGGGAGCACCGAGTGTTTCCTCTACACAGTCATGTCCTATGAT
CGCTACTTGGCCATCAGTTACCCGCTCAGGTACACCAGCATGATGAGTGGGAGCAGGTGT
GCCCTCCTGGCCACCGGCACTTGGCTCAGTGGCTCTCTGCACTCTGCTGTCCAGACCATA
TTGACTTTCCATTTGCCCTACTGTGGACCCAACCAGATCCAGCACTACTTCTGTGACGCA
CCGCCCATCCTGAAACTGGCCTGTGCAGACACCTCAGCCAACGTGATGGTCATCTTTGTG
GACATTGGGATAGTGGCCTCAGGCTGCTTTGTCCTGATAGTGCTGTCCTATGTGTCCATC
GTCTGTTCCATCCTGCGGATCCGCACCTCAGATGGGAGGCGCAGAGCCTTTCAGACCTGT
GCCTCCCACTGTATTGTGGTCCTTTGCTTCTTTGTTCCCTGTGTTGTCATTTATCTGAGG
CCAGGCTCCATGGATGCCATGGATGGAGTTGTGGCCATTTTCTACACTGTGCTGACGCCC
CTTCTCAACCCTGTTGTGTACACCCTGAGAAACAAGGAGGTGAAGAAAGCTGTGTTGAAA
CTTAGAGACAAAGTAGCACATCCTCAGAGGAAA

Conceptual translation

MSNASLVTAFILTGLPHAPGLDALLFGIFLVVYVLTVLGNLLILLVIRVDSHLHTPMYYF
LTNLSFIDMWFSTVTVPKMLMTLVSPSGRAISFHSCVAQLYFFHFLGSTECFLYTVMSYD
RYLAISYPLRYTSMMSGSRCALLATGTWLSGSLHSAVQTILTFHLPYCGPNQIQHYFCDA
PPILKLACADTSANVMVIFVDIGIVASGCFVLIVLSYVSIVCSILRIRTSDGRRRAFQTC
ASHCIVVLCFFVPCVVIYLRPGSMDAMDGVVAIFYTVLTPLLNPVVYTLRNKEVKKAVLK
LRDKVAHPQRK

Protein domains and features

Variations - SNPs

Chr	Start	End	Type	Variation	AA Change	SNP IDs
11	100	-100	NS	C/T	A/V	1000GP (YRI, YRI, YRI)
11	100	-100	SYN	A/G	A/A	1000GP (YRI, YRI, YRI)
11	123,886,290	123,886,290	NS	C/G	N/K	rs547870 (DbSNP)
11	123,886,308	123,886,308	SYN	A/G	A/A	rs11219407 (DbSNP)
11	123,886,320	123,886,320	SYN	A/G	T/T	rs12224056 (DbSNP)
11	123,886,352	123,886,352	NS	T/C	L/P	rs547068 (DbSNP)
11	123,886,395	123,886,394	Ins(1)	-/G		rs35933133 (DbSNP)
11	123,886,466	123,886,466	NS	C/T	T/I	rs12422129 (DbSNP)
11	123,886,583	123,886,583	NS	A/G	Y/C	rs4474449 (DbSNP)
11	123,886,681	123,886,681	NS	G/A	V/M	rs1893766 (DbSNP)
11	123,886,698	123,886,698	SYN	A/G	R/R	rs3017762 (DbSNP)
11	123,886,717	123,886,717	NS	T/G	C/G	rs503223 (DbSNP)
11	123,886,796	123,886,796	NS	A/G	Q/R	rs72472246 (DbSNP)
11	123,886,809	123,886,809	SYN	C/T	Y/Y	rs3017763 (DbSNP)
11	123,886,812	123,886,812	NS	C/G	F/L	rs3017764 (DbSNP)
11	123,886,822	123,886,822	NS	T/C	S/P	rs1893764 (DbSNP)
11	123,886,865	123,886,865	NS	A/T	E/V	rs4084209 (DbSNP)
11	123,886,958	123,886,958	NS	A/G	Q/R	rs11219408 (DbSNP)
11	123,886,984	123,886,984	NS	A/G	R/G	rs4936880 (DbSNP)
11	123,887,164	123,887,164	NS	A/C	K/Q	rs4936881 (DbSNP)
11	123,887,175	123,887,175	SYN	A/G	V/V	rs61908597 (DbSNP)
11	123,887,184	123,887,184	SYN	G/T	L/L	rs4936882 (DbSNP)
11	124,015,600	124,015,600	NS	C/T	A/V	1000GP (CEU, CHBJPT)
11	124,015,601	124,015,601	SYN	A/G	A/A	1000GP (CEU, CHBJPT)
11	124,015,613	124,015,613	SYN	A/G	T/T	1000GP (CEU, CHBJPT)
11	124,015,645	124,015,645	NS	T/C	L/P	1000GP (CEU)
11	124,016,277	124,016,277	NS	A/G	R/G	1000GP (CEU, CHBJPT)
11	124,016,477	124,016,477	SYN	T/G	L/L	1000GP (CEU, CHBJPT)

Variations - CNVs

Chr	Start	End	Type	Sources
11	123,885,722	123,894,275	CopyNumber	Variation_101364 (DGV)
11	123,886,182	123,889,214	Deletion	#293 (Waszak)

Haplotypes

Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.

	A9V	L24P	M134V	G146S	V195E	R226Q	R235G	K295Q	% Freq	CORP
1	A	L	M	G	V	R	R	K	31.34	0.138
2	V	L	V	G	E	R	G	Q	28.96	0.138
3	A	P	M	G	E	R	R	K	14.29	0.138
4	A	L	M	G	E	R	R	K	8.99	0.138
5	A	L	V	S	E	R	G	Q	6.37	0.138
6	A	L	V	G	E	R	G	Q	2.76	0.138
7	V	L	M	G	E	R	G	Q	1.46	0.138
8	A	L	M	S	E	R	G	Q	1.08	0.138
9	V	L	V	G	V	R	G	Q	0.69	0.138
10	V	L	V	G	E	R	G	K	0.54	0.138
11	A	L	M	G	E	R	G	Q	0.46	0.138
12	V	L	M	G	E	R	R	K	0.38	0.138
13	V	L	V	S	E	R	G	Q	0.31	0.138
14	V	L	V	G	V	R	R	K	0.31	0.138
15	A	L	M	S	E	R	R	K	0.31	0.138
16	A	L	V	S	E	R	G	K	0.23	0.138
17	A	L	M	G	V	R	G	Q	0.23	0.138
18	A	L	V	S	E	R	R	Q	0.15	0.138
19	A	L	V	S	E	Q	G	Q	0.15	0.138
20	A	L	V	G	V	R	G	Q	0.15	0.138
21	V	L	V	G	E	R	R	Q	0.15	0.138
22	A	L	M	S	E	R	G	K	0.08	0.138
23	V	L	V	S	E	R	R	K	0.08	0.138
24	A	P	M	G	V	R	R	K	0.08	0.138
25	V	L	M	G	V	R	R	K	0.08	0.138
26	V	L	V	S	V	R	G	Q	0.08	0.138
27	A	L	V	G	V	R	R	K	0.08	0.138
28	A	L	M	S	E	Q	G	Q	0.08	0.138
29	V	L	M	S	E	R	G	Q	0.08	0.138
30	V	L	M	G	V	R	G	Q	0.08	0.138

AceView Gene Models

The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.

Accession	Type		Chr	Start	End	Strand
OR10G4.aApr07-unspliced	main_exon	CDS	chr11	124,015,575	124,016,507	+
OR10G4.aApr07-unspliced	main_exon	3UTR	chr11	124,016,507	124,016,510	+

HORDE

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