OR10G8 Olfactory Receptor
| Gene Symbol | OR10G81 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | G |
| Pseudogene | No |
| CORP pseudogene probability score | 0.1 (functional) |
| Aliases | OR11-274, OR11-282, HsOR11.18.13, ORL3377 |
| External Ids | HGNC: 14845 GeneBank: AB065755, BK004510, BK004571, NM_001004464 ORDB: ORL3377 |
| Build #39 labels | OR10G8 |
| Chromosomal location | 11:124,029,623-124,030,555 (+) |
| Cluster | 11@124 |
| Synteny | CLIC#29 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10G4 | 87.14% | 311 |
| OR10G7 | 88.1% | 311 |
| OR10G9 | 88.1% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10G9 | 84% | 311 |
| Dog | OR10G9C | 84% | 311 |
| Dog | OR10G7 | 82% | 311 |
| Dog | OR10G7BP | 81% | 311 |
| Mouse | Or10g9 | 83% | 311 |
| Mouse | Or10g7 | 82% | 311 |
| Mouse | Or10g9b | 83% | 309 |
| Rat | Or10g9 | 83% | 309 |
| Rat | Or10g9b | 82% | 309 |
| Rat | Or10g7-ps | 81% | 311 |
| Cow | OR10G9D | 78% | 311 |
| Orang | OR10G9I | 92% | 311 |
| Horse | OR10G9 | 85% | 308 |
| Horse | OR10G9L | 83% | 310 |
| Chimp | OR10G9D | 95% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136920 |
Sequence information
| Nucleotide sequence |
ATGTCCAACGCCAGCCTACTGACAGCGTTCATCCTCATGGGCCTTCCCCATGCCCCAGCG CTGGACGCCCCCCTCTTTGGAGTCTTCCTGGTGGTTTACGTGCTCACTGTGCTGGGGAAC CTCCTCATCCTGCTGGTGATCAGGGTGGATTCTCACCTCCACACCACCATGTACTACTTC CTCACCAACCTGTCGTTCATTGACATGTGGTTCTCCACTGTCACGGTGCCCAAATTGCTG ATGACTTTGGTGTTCCCAAGTGGCAGGGCTATCTCCTTCCACAGCTGCATGGCTCAGCTC TATTTCTTTCACTTCCTAGGGGGCACCGAGTGTTTCCTCTACAGGGTCATGTCCTGTGAT CGCTACCTGGCCATCAGTTACCCGCTCAGGTACACCAGCATGATGACTGGGCGCTCGTGT ACTCTTCTGGCCACCAGCACTTGGCTCAGTGGCTCTCTGCACTCTGCTGTCCAGGCCATA TTGACTTTCCATTTGCCCTACTGTGGACCCAACTGGATCCAGCACTATTTGTGTGATGCA CCGCCCATCCTGAAACTGGCCTGTGCAGACACCTCAGCCATAGAGACTGTCATTTTTGTG ACTGTTGGAATAGTGGCCTCGGGCTGCTTTGTCCTGATAGTGCTGTCCTATGTGTCCATC GTCTGTTCCATCCTGCGGATCCGCACCTCAGAGGGGAAGCACAGAGCCTTTCAGACCTGT GCCTCCCACTGTATCGTGGTCCTTTGCTTCTTTGGCCCTGGTCTTTTCATTTACCTGAGG CCAGGCTCCAGGAAAGCTGTGGATGGAGTTGTGGCCGTTTTCTACACTGTGCTGACGCCC CTTCTCAACCCTGTTGTGTACACCCTGAGGAACAAGGAGGTGAAGAAAGCTCTGTTGAAG CTGAAAGACAAAGTAGCACATTCTCAGAGCAAA |
| Conceptual translation |
MSNASLLTAFILMGLPHAPALDAPLFGVFLVVYVLTVLGNLLILLVIRVDSHLHTTMYYF LTNLSFIDMWFSTVTVPKLLMTLVFPSGRAISFHSCMAQLYFFHFLGGTECFLYRVMSCD RYLAISYPLRYTSMMTGRSCTLLATSTWLSGSLHSAVQAILTFHLPYCGPNWIQHYLCDA PPILKLACADTSAIETVIFVTVGIVASGCFVLIVLSYVSIVCSILRIRTSEGKHRAFQTC ASHCIVVLCFFGPGLFIYLRPGSRKAVDGVVAVFYTVLTPLLNPVVYTLRNKEVKKALLK LKDKVAHSQSK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | G/A | R/H | 1000GP (YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | G/T | L/L | 1000GP (YRI) |
| 11 | 123,900,382 | 123,900,382 | NS | C/T | A/V | rs73028928 (DbSNP) |
| 11 | 123,900,385 | 123,900,385 | NS | A/C | Q/P | rs73028930 (DbSNP) |
| 11 | 123,900,401 | 123,900,401 | SYN | C/G | P/P | rs28485314 (DbSNP) |
| 11 | 123,900,866 | 123,900,866 | SYN | C/T | D/D | rs28711441 (DbSNP) |
| 11 | 123,901,175 | 123,901,175 | SYN | A/C | L/L | rs11825515 (DbSNP) |
| 11 | 124,029,664 | 124,029,664 | SYN | C/A | G/G | 1000GP (CHBJPT) |
| 11 | 124,029,987 | 124,029,987 | NS | A/G | Y/C | 1000GP (CHBJPT) |
| 11 | 124,030,209 | 124,030,209 | NS | C/T | T/I | 1000GP (CHBJPT) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 123,900,230 | 123,903,262 | Deletion | #228 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| P19Q | R121H | Y122C | C140Y | N171S | T196I | I213V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | P | R | Y | C | N | T | I | 85.41 | 0.255 |
| 2 | P | R | C | C | N | I | I | 6.68 | 0.182 |
| 3 | Q | R | Y | C | N | T | I | 4.22 | 0.255 |
| 4 | P | R | Y | Y | N | T | I | 2.23 | 0.255 |
| 5 | P | R | Y | C | N | T | V | 0.61 | 0.255 |
| 6 | P | R | Y | C | S | T | I | 0.38 | 0.255 |
| 7 | P | H | Y | C | N | T | I | 0.23 | 0.859 |
| 8 | P | R | C | C | N | T | I | 0.15 | 0.182 |
| 9 | Q | R | Y | C | S | T | I | 0.08 | 0.255 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10G8.aApr07-unspliced | main_exon | CDS | chr11 | 124,029,623 | 124,030,555 | + |
| 3UTR | chr11 | 124,030,555 | 124,030,558 | + | ||