OR10H1 Olfactory Receptor
| Gene Symbol | OR10H11 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | H |
| Pseudogene | No |
| CORP pseudogene probability score | 0.09 (functional) |
| Aliases | AC004510, OR19-27, HsOR19.4.4, ORL733, ORL525 |
| External Ids | HGNC: 8172 GeneBank: AF399584, BK004210, NM_013940 ORDB: ORL733, ORL525 |
| Build #39 labels | OR10H1 |
| Chromosomal location | 19:15,807,084-15,808,037 (-) |
| Cluster | 19@16a |
| Synteny | CLIC#46 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10H2 | 89.58% | 307 |
| OR10H5 | 93.61% | 313 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10H5B | 86% | 312 |
| Dog | OR10H1E | 86% | 312 |
| Dog | OR10H2 | 83% | 311 |
| Mouse | Or10h1 | 87% | 310 |
| Mouse | Or10h1b | 86% | 310 |
| Rat | Or10h1d | 87% | 310 |
| Rat | Or10h1c | 85% | 310 |
| Rat | Or10h1 | 87% | 300 |
| Cow | OR10H1F | 85% | 315 |
| Cow | OR10H1H | 87% | 309 |
| Cow | OR10H1I | 83% | 310 |
| Orang | OR10H5 | 92% | 310 |
| Orang | OR10H1JP | 93% | 241 |
| Horse | OR10H1KP | 80% | 314 |
| Chimp | OR10H2 | 89% | 307 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | CO246691 |
| mRNA | BC132969 |
| GNF Atlas2 | 208558_at |
Sequence information
| Nucleotide sequence |
ATGCAGAGAGCCAATCACTCCACAGTGACCCAATTCATCCTCGTCGGCTTCTCTGTCTTC CCCCACCTCCAGCTGATGCTCTTCCTGCTGTTCCTGCTGATGTACCTGTTCACGCTGCTG GGCAACCTGCTCATCATGGCCACCGTCTGGAGCGAGCGCAGCCTCCACACGCCCATGTAC CTCTTCCTGTGCGCCCTCTCCGTCTCCGAGATCCTCTACACCGTGGCCATCATCCCGCGC ATGCTGGCCGACCTGCTGTCCACCCAGCGCTCCATCGCCTTCCTGGCCTGTGCCAGTCAG ATGTTCTTCTCCTTCAGCTTCGGCTTCACCCACTCCTTCCTGCTCACCGTCATGGGCTAC GACCGCTACGTGGCCATCTGCCACCCCCTGCGCTACAACGTGCTCATGAGCCCGCGGGGC TGCGCCTGCCTGGTGGGCTGCTCCTGGGCTGGTGGCTTGGTCATGGGGATGGTGGTGACC TCGGCCATTTTCCACCTCGCCTTCTGTGGACACAAGGAGATCCACCATTTTGCTTGCCAT GTGCCACCTCTGTTGAAGTTGGCCTGTGGAGACGATGTGCTGGTGGTGGCCAAAGGCGTG GGCTTGGTGTGTATCACGGCCCTGCTGGGCTGTTTTCTCCTCATCCTCCTCTCCTATGCC TTCATCGTGGCCGCCATCTTGAAGATCCCTTCTGCTGAAGGTCGGAACAAGGCCTTCTCC ACCTGTGCCTCTCACCTCACTGTGGTGGTCGTGCACTATGGCTTTGCCTCCGTCATTTAC CTGAAGCCCAAAAGTCCCCAGTCTCTGGAAGGAGACACCTTGATGGGCATCACCTACACG GTCCTCACACCCTTCCTCAGCCCCATCATCTTCAGCCTCAGGAACAAGGAGCTGAAGGTC GCCATGAAGAAGACCTTCTTCAGTAAACTCTACCCAGAAAAAAATGTAATGATG |
| Conceptual translation |
MQRANHSTVTQFILVGFSVFPHLQLMLFLLFLLMYLFTLLGNLLIMATVWSERSLHTPMY LFLCALSVSEILYTVAIIPRMLADLLSTQRSIAFLACASQMFFSFSFGFTHSFLLTVMGY DRYVAICHPLRYNVLMSPRGCACLVGCSWAGGLVMGMVVTSAIFHLAFCGHKEIHHFACH VPPLLKLACGDDVLVVAKGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKAFS TCASHLTVVVVHYGFASVIYLKPKSPQSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKV AMKKTFFSKLYPEKNVMM Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 19 | 100 | -100 | NS | C/G | G/R | 1000GP (YRI) |
| 19 | 15,807,992 | 15,807,992 | NS | C/G | G/R | 1000GP (CEU, CHBJPT) |
| 19 | 15,918,008 | 15,918,008 | SYN | C/A | T/T | rs61745312 (DbSNP) |
| 19 | 15,918,177 | 15,918,177 | NS | G/T | A/D | rs62619246 (DbSNP) |
| 19 | 15,918,251 | 15,918,251 | SYN | G/A | G/G | rs61746476 (DbSNP) |
| 19 | 15,918,275 | 15,918,275 | SYN | G/A | D/D | rs61746475 (DbSNP) |
| 19 | 15,918,323 | 15,918,323 | NS | C/G | Q/H | rs1859298 (DbSNP) |
| 19 | 15,918,349 | 15,918,349 | NS | T/C | T/A | rs61745313 (DbSNP) |
| 19 | 15,918,380 | 15,918,380 | SYN | C/T | G/G | rs28426969 (DbSNP) |
| 19 | 15,918,390 | 15,918,390 | NS | A/G | L/S | rs4081569 (DbSNP) |
| 19 | 15,918,433 | 15,918,433 | NS | A/G | W/R | rs8103631 (DbSNP) |
| 19 | 15,918,434 | 15,918,434 | SYN | A/C/T | P/P | rs1859299 (DbSNP) |
| 19 | 15,918,455 | 15,918,455 | SYN | A/G | R/R | rs61739573 (DbSNP) |
| 19 | 15,918,647 | 15,918,647 | SYN | G/T | S/S | rs4081570 (DbSNP) |
| 19 | 15,918,654 | 15,918,654 | NS | A/G | V/A | rs4808382 (DbSNP) |
| 19 | 15,918,802 | 15,918,802 | NS | C/G | G/R | rs4808383 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 27 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| A167T | A142T | A65V | G16R | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | A | A | A | G | 83.03 | 0.148 |
| 2 | A | A | A | R | 13.29 | 0.148 |
| 3 | T | A | A | G | 1.69 | 0.148 |
| 4 | A | A | V | R | 1.54 | 0.148 |
| 5 | A | T | A | G | 0.46 | 0.148 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10H1.aApr07-unspliced | main_exon | 3UTR | chr19 | 15,807,003 | 15,807,084 | - |
| CDS | chr19 | 15,807,084 | 15,808,037 | - | ||
| 5UTR | chr19 | 15,808,037 | 15,808,126 | - | ||