OR10H3 Olfactory Receptor
| Gene Symbol | OR10H31 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | H |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | OR19-24, AC004597-B, HsOR19.4.2, ORL313, ORL527 |
| External Ids | HGNC: 8174 GeneBank: BK004212, NM_013938 ORDB: ORL313, ORL527 |
| Build #39 labels | OR10H3 |
| Chromosomal location | 19:15,741,393-15,742,340 (+) |
| Cluster | 19@16a |
| Synteny | CLIC#46 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10H4 | 89.87% | 316 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10H4 | 82% | 314 |
| Dog | OR10H4C | 82% | 308 |
| Dog | OR10H4D | 81% | 308 |
| Mouse | Or10h28 | 77% | 315 |
| Rat | Or10h28 | 78% | 315 |
| Cow | OR10H4P | 80% | 314 |
| Cow | OR10H4G | 81% | 308 |
| Cow | OR10H4H | 82% | 282 |
| Orang | OR10H4P | 87% | 278 |
| Horse | OR10H4 | 81% | 308 |
| Horse | OR10H4K | 83% | 282 |
| Horse | OR10H4L | 81% | 282 |
| Horse | OR10H4MP | 83% | 269 |
| Chimp | OR10H4 | 90% | 316 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB529277 |
| GNF Atlas2 | 208520_at |
Sequence information
| Nucleotide sequence |
ATGCCTGGTCAGAACTACAGAACCATATCTGAATTTATCCTCTCTGGCTTCTCAGCCTTC CCCCAGCAGCTCCTGCCTGTCTTGTTCCTGCTGTACCTCCTGATGTTCCTGTTCACATTG CTTGGCAACCTTCTTATCATGGCCACAGTTTGGATTGAACGCAGACTCCACACACCCATG TACCTCTTCTTGTGTGCCCTCTCCATCTCTGAGATTCTGTTCACTGTTGCCATCACCCCT CGCATGCTGGCTGATCTGCTCTTCACCCATCGTTCCATCACCTTTGTGGCTTGTGCCATT CAGATGTTCTTCTCCTTCATGTTTGGCTTCACTCACTCCTTCCTTCTCATGGTCATGGGC TATGATCACTACGTGACCATCTGCCACCCACTGCATTACAACATGCTAATGAGTCCCCGT GGCTGTGCCCATCTTGTGGCCTGGACCTGGGCTGGTGGCTCGGTCATGGGGATGATGGTG ACAATGATGGTTTTTCACCTCACTTTCTGTGGGTCTAATGTGATCCACCATTTTCTCTGT CATGTGCTTTCCCTCTTGAAGTTGGCCTGTGGGAGCAAGACATCATCTGTCATCATGGGT GTGATGCTGGTGTGTGTCACAGCCCTGATAGGCTGTTTGTTCCTCATCATCCTCTCCTTT GTCTTCATTGTGGCTGCCATCTTGAGGATTCCTTCTGCTGAGGGCCGGCACAAGACTTTC TCCACTTGTGTATCCCACCTCACTGTGGTGGTCATGCACTATAGTTTTGCCTCCCTTATC TACCTCAAACCCAAGGGCCTCCATTCTATGTACAGTGATGCCTTGATGGCCACCACCTAT ACTGTCTTCACCCCCTTCCTCAGCCCAATCATTTTCAGTCTAAGGAACAAGGAGCTGAAG AATGCCATAAATAAAAACTTTTGCAGAAGGTTCTGCCCTCTAAGCTCC |
| Conceptual translation |
MPGQNYRTISEFILSGFSAFPQQLLPVLFLLYLLMFLFTLLGNLLIMATVWIERRLHTPM YLFLCALSISEILFTVAITPRMLADLLFTHRSITFVACAIQMFFSFMFGFTHSFLLMVMG YDHYVTICHPLHYNMLMSPRGCAHLVAWTWAGGSVMGMMVTMMVFHLTFCGSNVIHHFLC HVLSLLKLACGSKTSSVIMGVMLVCVTALIGCLFLIILSFVFIVAAILRIPSAEGRHKTF STCVSHLTVVVMHYSFASLIYLKPKGLHSMYSDALMATTYTVFTPFLSPIIFSLRNKELK NAINKNFCRRFCPLSS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 19 | 100 | -100 | NS | A/C | R/S | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 19 | 100 | -100 | SYN | C/T | F/F | 1000GP (YRI, YRI) |
| 19 | 15,741,413 | 15,741,413 | NS | A/C | R/S | 1000GP (CEU, CHBJPT) |
| 19 | 15,741,432 | 15,741,432 | NS | C/A | L/I | 1000GP (CEU, CHBJPT) |
| 19 | 15,741,553 | 15,741,553 | NS | G/A | R/H | 1000GP (CEU, CHBJPT) |
| 19 | 15,741,685 | 15,741,685 | NS | G/T | C/F | 1000GP (CHBJPT) |
| 19 | 15,741,734 | 15,741,734 | SYN | C/T | F/F | 1000GP (CEU) |
| 19 | 15,742,062 | 15,742,062 | NS | G/A | V/M | 1000GP (CEU, CHBJPT) |
| 19 | 15,742,270 | 15,742,270 | NS | G/A | S/N | 1000GP (CEU, CHBJPT) |
| 19 | 15,852,223 | 15,852,223 | NS | A/C | R/S | rs1966357 (DbSNP) |
| 19 | 15,852,242 | 15,852,242 | NS | A/C | I/L | rs2240227 (DbSNP) |
| 19 | 15,852,363 | 15,852,363 | NS | A/G | H/R | rs11670007 (DbSNP) |
| 19 | 15,852,544 | 15,852,544 | SYN | C/T | F/F | rs11670326 (DbSNP) |
| 19 | 15,852,872 | 15,852,872 | NS | A/G | M/V | rs2240228 (DbSNP) |
| 19 | 15,853,080 | 15,853,080 | NS | A/G | N/S | rs2240229 (DbSNP) |
| 19 | 15,853,150 | 15,853,150 | SYN | C/T | S/S | rs16980824 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 19 | 15,786,059 | 15,888,458 | Inversion | Variation_43709 (DGV) |
| 19 | 15,852,103 | 15,855,150 | CopyNumber | #102 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R7S | L14I | F36S | R54H | Y121C | V224M | S293N | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | S | L | F | H | Y | V | S | 25.81 | 1.000 |
| 2 | S | L | F | R | Y | M | S | 20.89 | 1.000 |
| 3 | R | I | F | R | Y | V | S | 19.43 | 1.000 |
| 4 | S | L | F | R | Y | V | N | 15.05 | 1.000 |
| 5 | R | L | F | R | Y | V | S | 14.36 | 1.000 |
| 6 | S | L | F | R | Y | V | S | 3.84 | 1.000 |
| 7 | R | L | F | R | Y | M | S | 0.15 | 1.000 |
| 8 | R | I | F | R | Y | V | N | 0.15 | 1.000 |
| 9 | S | L | F | H | Y | M | S | 0.08 | 1.000 |
| 10 | R | L | F | R | C | V | S | 0.08 | 1.000 |
| 11 | R | L | F | R | Y | V | N | 0.08 | 1.000 |
| 12 | S | L | S | R | Y | V | N | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10H3.aApr07-unspliced | main_exon | CDS | chr19 | 15,741,393 | 15,742,340 | + |
| 3UTR | chr19 | 15,742,340 | 15,742,343 | + | ||