OR10H5 Olfactory Receptor
| Gene Symbol | OR10H51 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | H |
| Pseudogene | No |
| CORP pseudogene probability score | 0.09 (functional) |
| Aliases | OR19-25, OR19-26, HsOR19.4.3, ORL3761 |
| External Ids | HGNC: 15389 GeneBank: AB065920, AF399583, BK004271, BK004272, NM_001004466 ORDB: ORL3761 |
| Build #39 labels | OR10H5 |
| Chromosomal location | 19:15,794,049-15,794,993 (+) |
| Cluster | 19@16a |
| Synteny | CLIC#46 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10H1 | 93.61% | 313 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10H5B | 86% | 313 |
| Dog | OR10H1E | 86% | 313 |
| Dog | OR10H1 | 84% | 314 |
| Dog | OR10H2 | 83% | 313 |
| Mouse | Or10h1 | 85% | 314 |
| Mouse | Or10h1b | 84% | 314 |
| Rat | Or10h1c | 85% | 312 |
| Rat | Or10h1d | 84% | 312 |
| Rat | Or10h1 | 86% | 302 |
| Cow | OR10H1 | 86% | 314 |
| Cow | OR10H1F | 85% | 311 |
| Cow | OR10H1H | 85% | 311 |
| Orang | OR10H1 | 91% | 314 |
| Orang | OR10H1JP | 90% | 241 |
| Horse | OR10H1 | 78% | 314 |
| Chimp | OR10H2 | 87% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB529278 |
Sequence information
| Nucleotide sequence |
ATGCAGGGGCTAAACCACACCTCCGTGTCTGAATTCATCCTCGTTGGCTTCTCTGCCTTC CCCCACCTCCAGCTGATGCTCTTCCTGCTGTTCCTGCTGATGTACCTGTTCACGCTGCTG GGCAACCTGCTCATCATGGCCACTGTCTGGAGCGAGCGCAGCCTCCACATGCCCATGTAC CTCTTCCTGTGTGCCCTCTCCATCACCGAGATCCTCTACACCGTGGCCATCATCCCGCGC ATGCTGGCCGACCTGCTGTCCACCCAGCGCTCCATCGCCTTCCTGGCCTGTGCCAGTCAG ATGTTCTTCTCCTTCAGCTTCGGCTTCACCCACTCCTTCCTGCTCACTGTCATGGGCTAC GACCGCTACGTGGCCATCTGCCACCCCCTGCGTTACAACGTGCTCATGAGCCTGCGGGGC TGCACCTGCCGGGTGGGCTGCTCCTGGGCTGGTGGCTTGGTCATGGGGATGGTGGTGACC TCGGCCATTTTCCACCTCGCCTTCTGTGGACACAAGGAGATCCACCATTTCTTCTGCCAC GTGCCACCTCTGTTGAAGTTGGCCTGTGGAGATGATGTGCTGGTGGTGGCCAAAGGCGTG GGCTTGGTGTGTATCACGGCCCTGCTGGGCTGTTTTCTCCTCATCCTCCTCTCCTATGCC TTCATCGTGGCCGCCATCTTGAAGATCCCTTCTGCTGAAGGTCGGAACAAGGCCTTCTCC ACCTGTGCCTCTCACCTCACTGTGGTGGTCGTGCACTATGGCTTTGCCTCCGTCATTTAC CTGAAGCCCAAAGGTCCCCAGTCTCCGGAAGGAGACACCTTGATGGGCATCACCTACACG GTCCTCACACCCTTCCTCAGCCCCATCATCTTCAGCCTCAGGAACAAGGAGCTGAAGGTC GCCATGAAGAAGACTTGCTTCACCAAACTCTTTCCACAGAACTGC |
| Conceptual translation |
MQGLNHTSVSEFILVGFSAFPHLQLMLFLLFLLMYLFTLLGNLLIMATVWSERSLHMPMY LFLCALSITEILYTVAIIPRMLADLLSTQRSIAFLACASQMFFSFSFGFTHSFLLTVMGY DRYVAICHPLRYNVLMSLRGCTCRVGCSWAGGLVMGMVVTSAIFHLAFCGHKEIHHFFCH VPPLLKLACGDDVLVVAKGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKAFS TCASHLTVVVVHYGFASVIYLKPKGPQSPEGDTLMGITYTVLTPFLSPIIFSLRNKELKV AMKKTCFTKLFPQNC Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 19 | 100 | -100 | NS | G/A | G/S | 1000GP (YRI, YRI, YRI) |
| 19 | 100 | -100 | SYN | C/T | L/L | 1000GP (YRI, YRI, YRI, YRI) |
| 19 | 15,794,192 | 15,794,192 | SYN | T/C | T/T | 1000GP (CEU) |
| 19 | 15,794,396 | 15,794,396 | SYN | T/C | T/T | 1000GP (CEU) |
| 19 | 15,794,479 | 15,794,479 | NS | G/T | R/L | 1000GP (CEU, CHBJPT) |
| 19 | 15,794,621 | 15,794,621 | SYN | T/C | D/D | 1000GP (CEU) |
| 19 | 15,794,851 | 15,794,851 | NS | C/A | S/Y | 1000GP (CEU) |
| 19 | 15,902,588 | 15,902,589 | large insertion | 8016bp insertion | rs72095917 (DbSNP) | |
| 19 | 15,904,972 | 15,904,972 | SYN | A/G | T/T | rs61741283 (DbSNP) |
| 19 | 15,904,977 | 15,904,977 | NS | A/T | Q/L | rs61741282 (DbSNP) |
| 19 | 15,905,002 | 15,905,002 | SYN | C/T | T/T | rs4808379 (DbSNP) |
| 19 | 15,905,086 | 15,905,086 | SYN | C/T | A/A | rs61748357 (DbSNP) |
| 19 | 15,905,179 | 15,905,179 | SYN | C/T | F/F | rs61748264 (DbSNP) |
| 19 | 15,905,206 | 15,905,206 | SYN | C/T | T/T | rs4808380 (DbSNP) |
| 19 | 15,905,271 | 15,905,271 | NS | C/T | P/L | rs61754881 (DbSNP) |
| 19 | 15,905,276 | 15,905,276 | NS | A/G | S/G | rs61754880 (DbSNP) |
| 19 | 15,905,289 | 15,905,289 | NS | G/T | R/L | rs61754873 (DbSNP) |
| 19 | 15,905,414 | 15,905,414 | NS | A/C | K/Q | rs61741438 (DbSNP) |
| 19 | 15,905,431 | 15,905,431 | SYN | C/T | D/D | rs4808381 (DbSNP) |
| 19 | 15,905,468 | 15,905,468 | NS | G/T | G/C | rs62106065 (DbSNP) |
| 19 | 15,905,505 | 15,905,505 | NS | C/T | P/L | rs62106066 (DbSNP) |
| 19 | 15,905,529 | 15,905,529 | NS | A/C | D/A | rs62621417 (DbSNP) |
| 19 | 15,905,639 | 15,905,639 | SYN | T/C | L/L | rs3746151 (DbSNP) |
| 19 | 15,905,661 | 15,905,661 | NS | A/C | Y/S | rs67455341 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 19 | 15,875,235 | 15,905,462 | CopyNumber | Variation_35612 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| E11D | A19V | G140S | R144L | K186Q | S268Y | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | E | A | G | R | K | S | 66.74 | 0.148 |
| 2 | E | A | G | R | K | Y | 22.35 | 0.148 |
| 3 | E | A | G | L | K | S | 8.83 | 0.148 |
| 4 | E | A | S | R | K | Y | 1.15 | 0.148 |
| 5 | E | A | G | L | K | Y | 0.31 | 0.148 |
| 6 | E | V | G | R | K | Y | 0.31 | 0.148 |
| 7 | D | A | G | R | K | S | 0.15 | 0.148 |
| 8 | E | A | G | R | Q | S | 0.15 | 0.148 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10H5.aApr07-unspliced | main_exon | CDS | chr19 | 15,794,049 | 15,794,993 | + |
| 3UTR | chr19 | 15,794,993 | 15,794,996 | + | ||