OR10J1 Olfactory Receptor
| Gene Symbol | OR10J11 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | J |
| Pseudogene | No |
| CORP pseudogene probability score | 0.19 (functional) |
| Aliases | OR1-26, HSHGMP07J, HsOR1.4.26, ORL21 |
| External Ids | HGNC: 8175 GeneBank: AF399587, BC069150, BK004527, HSHGMP07J, NM_012351 ORDB: ORL21 |
| Build #39 labels | OR10J1 |
| Chromosomal location | 1:159,439,792-159,440,718 (+) |
| Cluster | 1@159b |
| Synteny | CLIC#4 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10J2P | 77.45% | 306 |
| OR10J8P | 79.94% | 309 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10J8 | 80% | 309 |
| Mouse | Or10j2 | 80% | 305 |
| Rat | Or10j2 | 79% | 307 |
| Cow | OR10J1B | 89% | 280 |
| Orang | OR10J1P | 96% | 309 |
| Horse | OR10J1C | 83% | 309 |
| Horse | OR10J2 | 80% | 307 |
| Chimp | OR10J1P | 98% | 309 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | DA686268 |
| mRNA | BC069150 |
| GNF Atlas2 | 221346_at |
Sequence information
| Nucleotide sequence |
ATGAAAAGAGAGAACTTTACTCTCATCACTGACTTTGTTTTCCAAGGTTTCTCTAGCTTC CATGAGCAGCAGATCACCCTTTTTGGCGTGTTCCTTGCACTATACATCTTAACCTTAGCA GGCAATATCATCATTGTGACCATCATCCGAATGGATCTTCATCTTCACACACCCATGTAC TTCTTCCTGAGCATGCTGTCCACTTCAGAGACTGTATATACATTGGTCATTCTCCCAAGA ATGCTCTCCAGCCTCGTAGGTATGAGCCAGCCCATATCATTGGCAGGGTGTGCCACACAG ATGTTCTTTTTTGTAACCTTTGGCATCACTAACTGCTTCCTGCTCACAGCAATGGGATAT GACCGCTATGTGGCCATCTGCAACCCCCTGAGATACATGGTTATTATGAACAAGAGGCTG CGTATCCAACTTGTCCTGGGGGCCTGCAGCATTGGGCTGATTGTAGCAATAACGCAAGTG ACATCTGTATTCAGGTTACCCTTCTGTGCTAGAAAGGTGCCCCACTTCTTCTGTGACATC CGCCCTGTGATGAAGCTCTCCTGCATTGACACCACTGTCAATGAAATCCTGACTTTGATT ATCAGTGTGCTGGTGCTTGTTGTACCTATGGGTCTGGTTTTCATTTCTTATGTTCTCATT ATCTCTACAATCCTCAAGATTGCTTCAGTTGAGGGCCGGAAGAAGGCTTTTGCCACCTGT GCATCCCACCTCACTGTGGTCATTGTCCACTACAGCTGTGCCTCCATTGCCTACCTCAAG CCCAAGTCAGAGAACACCAGAGAACATGACCAGCTGATCTCGGTGACCTACACTGTCATC ACTCCCCTACTGAACCCTGTGGTATACACCCTGAGAAATAAAGAGGTCAAAGATGCTCTG TGCAGGGCTGTTGGTGGGAAGTTTTCC |
| Conceptual translation |
MKRENFTLITDFVFQGFSSFHEQQITLFGVFLALYILTLAGNIIIVTIIRMDLHLHTPMY FFLSMLSTSETVYTLVILPRMLSSLVGMSQPISLAGCATQMFFFVTFGITNCFLLTAMGY DRYVAICNPLRYMVIMNKRLRIQLVLGACSIGLIVAITQVTSVFRLPFCARKVPHFFCDI RPVMKLSCIDTTVNEILTLIISVLVLVVPMGLVFISYVLIISTILKIASVEGRKKAFATC ASHLTVVIVHYSCASIAYLKPKSENTREHDQLISVTYTVITPLLNPVVYTLRNKEVKDAL CRAVGGKFS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | nonsense SNP | T/A | C/* | 1000GP (YRI) |
| 1 | 100 | -100 | NS | G/T | M/I | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | C/T | N/N | 1000GP (YRI, YRI) |
| 1 | 159,409,612 | 159,409,612 | NS | A/G | N/D | rs62641745 (DbSNP) |
| 1 | 159,409,676 | 159,409,675 | Ins(1) | -/C | rs35762410 (DbSNP) | |
| 1 | 159,409,734 | 159,409,734 | NS | G/T | M/I | rs10908722 (DbSNP) |
| 1 | 159,409,757 | 159,409,757 | NS | C/T | T/M | rs35634161 (DbSNP) |
| 1 | 159,409,857 | 159,409,857 | NS | A/G | I/M | rs12048482 (DbSNP) |
| 1 | 159,409,884 | 159,409,884 | NS | A/G | I/M | rs12118628 (DbSNP) |
| 1 | 159,409,965 | 159,409,965 | SYN | C/T | N/N | rs12070985 (DbSNP) |
| 1 | 159,410,103 | 159,410,103 | SYN | C/G | P/P | rs62641747 (DbSNP) |
| 1 | 159,410,217 | 159,410,217 | SYN | A/G | L/L | rs41264477 (DbSNP) |
| 1 | 159,410,340 | 159,410,340 | nonsense SNP | A/T | */C | rs12409540 (DbSNP) |
| 1 | 159,410,354 | 159,410,354 | NS | A/T | Y/F | rs41264479 (DbSNP) |
| 1 | 159,439,920 | 159,439,920 | SYN | C/A | I/I | 1000GP (CHBJPT) |
| 1 | 159,439,967 | 159,439,967 | NS | T/C | M/T | 1000GP (CEU, CHBJPT) |
| 1 | 159,440,067 | 159,440,067 | NS | A/G | I/M | 1000GP (CEU, CHBJPT) |
| 1 | 159,440,094 | 159,440,094 | NS | G/A | M/I | 1000GP (CEU, CHBJPT) |
| 1 | 159,440,217 | 159,440,217 | SYN | C/T | I/I | 1000GP (CHBJPT) |
| 1 | 159,440,427 | 159,440,427 | SYN | G/A | L/L | 1000GP (CEU) |
| 1 | 159,440,550 | 159,440,550 | nonsense SNP | T/A | C/* | 1000GP (CEU) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| M218I | M226T | I259M | M268I | T277I | M300R | C264* | Y269F | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | I | M | M | M | T | M | C | Y | 45.70 | 0.347 |
| 2 | I | M | I | M | T | M | C | Y | 27.34 | 0.347 |
| 3 | I | M | I | I | T | M | C | Y | 13.52 | 0.347 |
| 4 | I | M | I | M | T | M | * | Y | 7.14 | 1.200 |
| 5 | I | T | I | M | T | M | C | Y | 3.61 | 0.347 |
| 6 | M | M | I | M | T | M | C | Y | 0.84 | 0.347 |
| 7 | I | M | I | M | I | M | C | Y | 0.77 | 0.347 |
| 8 | I | M | M | M | T | R | C | Y | 0.69 | 0.347 |
| 9 | I | M | M | M | T | M | C | F | 0.23 | 0.347 |
| 10 | I | M | M | M | T | M | * | Y | 0.08 | 1.200 |
| 11 | I | M | I | I | T | M | * | Y | 0.08 | 1.200 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10J1.aApr07-unspliced | main_exon | 5UTR | chr1 | 159,439,722 | 159,439,792 | + |
| CDS | chr1 | 159,439,792 | 159,440,718 | + | ||
| 3UTR | chr1 | 159,440,718 | 159,440,811 | + | ||