OR10S1 Olfactory Receptor
| Gene Symbol | OR10S11 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | S |
| Pseudogene | No |
| CORP pseudogene probability score | 0.76 (pseudogene) |
| Aliases | OR11-279, HsOR11.18.8, ORL3374, ORL3375 |
| External Ids | HGNC: 14807 GeneBank: AB065758, AF399565, BK004509, NM_001004474 ORDB: ORL3374, ORL3375 |
| Build #39 labels | OR10S1 |
| Chromosomal location | 11:123,976,699-123,977,658 (-) |
| Cluster | 11@124 |
| Synteny | CLIC#29 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10G1P | 57.38% | 298 |
| OR10G4 | 54.52% | 299 |
| OR10G7 | 54.18% | 299 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10G6 | 58% | 299 |
| Mouse | Or10s1 | 87% | 314 |
| Rat | Or10s1 | 84% | 317 |
| Cow | OR10G6 | 56% | 302 |
| Orang | OR10G1P | 56% | 305 |
| Horse | OR10G6 | 57% | 303 |
| Chimp | OR10G1 | 57% | 305 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC137038 |
| GNF Atlas2 | gnf1h05562_at |
Sequence information
| Nucleotide sequence |
ATGACAACGGAGAACCCCAACCAGACTGTGGTGAGCCACTTCTTCCTGGAGGGTTTGAGG TACACCGCTAAACATTCTAGCCTCTTCTTCCTCCTCTTCCTCCTCATCTACAGCATCACT GTGGCTGGGAATCTCCTCATCCTCCTAACTGTGGGCTCTGACTCTCACCTCAGCTTACCC ATGTACCACTTCCTGGGGCACCTCTCCTTCCTGGATGCCTGTTTGTCTACAGTGACAGTG CCCAAGGTCATGGCAGGCCTGCTGACTCTGGATGGGAAGGTGATCTCCTTTGAGGGCTGT GCCGTACAGCTTTATTGCTTCCACTTTCTGGCCAGCACTGAGTGCTTCCTGTACACAGTC ATGGCCTATGACCGCTATCTGGCTATCTGTCAACCCCTGCACTACCCAGTGGCCATGAAC AGAAGGATGTGTGCAGAAATGGCTGGAATCACCTGGGCCATAGGTGCCACGCACGCTGCA ATCCACACCTCCCTCACCTTCCGCCTGCTCTACTGTGGGCCTTGCCACATTGCCTACTTC TTCTGCGACATACCCCCTGTCCTAAAGCTCGCCTGTACAGACACCACCATTAATGAGCTA GTCATGCTTGCCAGCATTGGCATCGTGGCTGCAGGCTGCCTCATCCTCATCGTTATTTCC TACATCTTCATCGTGGCAGCTGTGTTGCGCATCCGCACAGCCCAGGGCCGGCAGCGGGCC TTCTCCCCCTGCACTGCCCAGCTCACTGGGGTGCTCCTGTACTACGTGCCACCTGTCTGT ATCTACCTGCAGCCTCGCTCCAGTGAGGCAGGAGCTGGGGCCCCTGCTGTCTTCTACACA ATCGTAACTCCAATGCTCAACCCATTCATTTACACTTTGCGGAACAAGGAGGTGAAGCAT GCTCTGCAAAGGCTTTTGTGCAGCAGCTTCCGAGAGTCTACAGCAGGCAGCCCACCCCCA |
| Conceptual translation |
MTTENPNQTVVSHFFLEGLRYTAKHSSLFFLLFLLIYSITVAGNLLILLTVGSDSHLSLP MYHFLGHLSFLDACLSTVTVPKVMAGLLTLDGKVISFEGCAVQLYCFHFLASTECFLYTV MAYDRYLAICQPLHYPVAMNRRMCAEMAGITWAIGATHAAIHTSLTFRLLYCGPCHIAYF FCDIPPVLKLACTDTTINELVMLASIGIVAAGCLILIVISYIFIVAAVLRIRTAQGRQRA FSPCTAQLTGVLLYYVPPVCIYLQPRSSEAGAGAPAVFYTIVTPMLNPFIYTLRNKEVKH ALQRLLCSSFRESTAGSPPP Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | A/G | V/A | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | T/G | P/P | 1000GP (YRI) |
| 11 | 123,847,473 | 123,847,473 | NS | A/G | V/A | rs55944888 (DbSNP) |
| 11 | 123,847,659 | 123,847,659 | NS | C/T | G/D | rs35682880 (DbSNP) |
| 11 | 123,848,064 | 123,848,064 | NS | A/G | V/A | rs17759447 (DbSNP) |
| 11 | 123,848,110 | 123,848,110 | NS | A/C | C/G | rs11219384 (DbSNP) |
| 11 | 123,848,121 | 123,848,121 | NS | C/T | R/K | rs17686210 (DbSNP) |
| 11 | 123,848,212 | 123,848,212 | NS | C/T | G/S | rs17759513 (DbSNP) |
| 11 | 123,976,766 | 123,976,766 | NS | A/G | V/A | 1000GP (CEU, CHBJPT) |
| 11 | 123,977,414 | 123,977,414 | NS | T/C | K/R | 1000GP (CEU, CHBJPT) |
| 11 | 123,977,505 | 123,977,505 | NS | C/T | G/S | 1000GP (CEU, CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| V309A | A281T | I230T | A112V | K93R | G63S | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | V | A | I | A | K | G | 76.04 | 0.866 |
| 2 | A | A | I | A | R | S | 12.44 | 0.866 |
| 3 | V | A | I | A | R | S | 7.99 | 0.866 |
| 4 | V | T | I | A | K | G | 1.84 | 0.866 |
| 5 | V | A | I | A | R | G | 1.00 | 0.866 |
| 6 | V | A | T | A | K | G | 0.31 | 0.866 |
| 7 | V | A | I | V | K | G | 0.23 | 0.866 |
| 8 | A | A | I | A | K | G | 0.15 | 0.866 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10S1.aApr07-unspliced | main_exon | 3UTR | chr11 | 123,976,696 | 123,976,699 | - |
| CDS | chr11 | 123,976,699 | 123,977,658 | - | ||
| 5UTR | chr11 | 123,977,658 | 123,977,691 | - | ||