OR10X1 Olfactory Receptor
| Gene Symbol | OR10X11 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | X |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | OR1-14, OR1-13, HsOR1.4.9 |
| External Ids | HGNC: 14995 GeneBank: AB065636, AF399455, BK004194, BK004529, NM_001004477 |
| Build #39 labels | OR10X1P |
| Chromosomal location | 1:158,578,922-158,579,848 (-) |
| Cluster | 1@159a |
| Synteny | CLIC#4 |
| Remarks | Segregating Pseudo Gene, a nonsynonymous SNP rs863362 (AA change=W/* ) |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10H1 | 50% | 302 |
| OR10H2 | 49.51% | 309 |
| OR10R3P | 50.66% | 304 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10R3 | 51% | 309 |
| Mouse | Or10x1 | 83% | 310 |
| Rat | Or10x1b | 83% | 310 |
| Rat | Or10x1 | 82% | 309 |
| Cow | OR10X1D | 84% | 310 |
| Cow | OR10X1C | 83% | 310 |
| Orang | OR10X1P | 96% | 309 |
| Horse | OR10X1E | 85% | 310 |
| Chimp | OR10R2 | 50% | 308 |
Sequence information
| Nucleotide sequence |
ATGAAGATCAACCAGACAATCCTGAAGGAATTCATTCTTGTTGGCTTTTCTGTGTACCCA CATGTACAGACATTTCTTTTTGTGGTCTTCTTTTGTCTCTACCTTCTCACCCTTGCAGGT AATCTGATCATCATGGGTCTAACTTGGGTGGACAGGTCCCTCCACACCCCTATGTATCTC TTCCTTAGTGCACTCTCCTTCTCTGAGACCTGCTATACGCTGACCATCGTCCCCAAGATG CTGGAAGATCTACTGGCCAAGGACAGAAGCATTTCAGTCACAGGTTGTAGCTTACAGATG TGCTTCTTCTTGGGACTTGGTGGCACAAACTGTATCATTCTCACTTTGATGGGATATGAC CGCTTCCTGGCCATCTGTAACCCTCTAAGATATCCACTGCTTATGACCAACATTGTATGT GGACAACTTGTGGCCTCTGCTTGCACTGCAGGCTTCTTTATCTCTCTTACAGAGACTGCA CTGATATTCAGGGACTCTTTCTGCAGACCCAACCTTGTCAAACACTTCTTCTGCCATATG CTGGCAGTTATTAGGCTGTCTTGTATAGACAGTAACCACACAGAATTCATTATAACACTG ATCTCAGTGTCTGGTTTGCTGGGTACCCTTCTGCTCATCATCCTGACTGATGTCTTCATT ATTTCTACTGTCCTCAGGATCCCTTCAGCTGAGGGCAAGCAGAAGGCCTTCACCACCTGT GCCTCCCACCTCACCGTGGTTATAATCCACTTTGGTTTTGCATCTATTGTTTATTTGAAG CCAGAAGCCTCAGGAGATGACACACTCATAGCAGTCCCTTATACTGTCATTACCCCCTTC CTCAGCCCCATCATATTCAGCCTGAGGAATAAGGACATGAAAAATGCTTTTAGAAGAATG ATGGGAAACACAGTTGCCTTGAAAAAA |
| Conceptual translation |
MKINQTILKEFILVGFSVYPHVQTFLFVVFFCLYLLTLAGNLIIMGLTWVDRSLHTPMYL FLSALSFSETCYTLTIVPKMLEDLLAKDRSISVTGCSLQMCFFLGLGGTNCIILTLMGYD RFLAICNPLRYPLLMTNIVCGQLVASACTAGFFISLTETALIFRDSFCRPNLVKHFFCHM LAVIRLSCIDSNHTEFIITLISVSGLLGTLLLIILTDVFIISTVLRIPSAEGKQKAFTTC ASHLTVVIIHFGFASIVYLKPEASGDDTLIAVPYTVITPFLSPIIFSLRNKDMKNAFRRM MGNTVALKK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | nonsense SNP | C/T | W/* | 1000GP (YRI) |
| 1 | 100 | -100 | NS | C/T | V/M | 1000GP (YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | G/A | P/P | 1000GP (YRI, YRI, YRI) |
| 1 | 158,548,788 | 158,548,788 | NS | A/G | I/T | rs72698782 (DbSNP) |
| 1 | 158,548,802 | 158,548,802 | SYN | A/G | P/P | rs36102561 (DbSNP) |
| 1 | 158,548,903 | 158,548,903 | NS | C/T | V/M | rs73016227 (DbSNP) |
| 1 | 158,548,922 | 158,548,922 | SYN | C/G | T/T | rs36024740 (DbSNP) |
| 1 | 158,548,931 | 158,548,931 | SYN | A/G | A/A | rs35360113 (DbSNP) |
| 1 | 158,549,082 | 158,549,082 | NS | A/T | L/Q | rs61755876 (DbSNP) |
| 1 | 158,549,151 | 158,549,151 | NS | A/C | F/C | rs41273505 (DbSNP) |
| 1 | 158,549,152 | 158,549,152 | NS | A/G | F/L | rs16840360 (DbSNP) |
| 1 | 158,549,176 | 158,549,176 | NS | A/G | S/P | rs7550131 (DbSNP) |
| 1 | 158,549,264 | 158,549,264 | SYN | A/G | I/I | rs863360 (DbSNP) |
| 1 | 158,549,277 | 158,549,277 | NS | C/T | R/H | rs41273507 (DbSNP) |
| 1 | 158,549,339 | 158,549,339 | NS | C/T | M/I | rs41273509 (DbSNP) |
| 1 | 158,549,402 | 158,549,401 | Ins(1) | -/A | rs35095271 (DbSNP) | |
| 1 | 158,549,420 | 158,549,420 | SYN | C/T | T/T | rs863361 (DbSNP) |
| 1 | 158,549,449 | 158,549,449 | NS | C/A | A/S | rs950164 (DbSNP) |
| 1 | 158,549,492 | 158,549,492 | nonsense SNP | C/T | W/* | rs863362 (DbSNP) |
| 1 | 158,549,511 | 158,549,511 | NS | A/G | I/T | rs863363 (DbSNP) |
| 1 | 158,579,420 | 158,579,420 | SYN | A/G | L/L | 1000GP (CEU) |
| 1 | 158,579,474 | 158,579,474 | SYN | G/A | I/I | 1000GP (CEU, CHBJPT) |
| 1 | 158,579,549 | 158,579,549 | NS | C/T | M/I | 1000GP (CEU) |
| 1 | 158,579,630 | 158,579,630 | SYN | C/T | T/T | 1000GP (CEU, CHBJPT) |
| 1 | 158,579,631 | 158,579,631 | NS | G/A | T/M | 1000GP (CEU) |
| 1 | 158,579,659 | 158,579,659 | NS | C/A | A/S | 1000GP (CEU) |
| 1 | 158,579,702 | 158,579,702 | nonsense SNP | C/T | W/* | 1000GP (CEU, CHBJPT) |
| 1 | 158,579,721 | 158,579,721 | NS | A/G | I/T | 1000GP (CEU, CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| V246M | S204A | L186Q | S155P | T73M | A64S | W49* | I43T | I7V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | V | S | L | S | T | A | * | T | I | 51.00 | 1.200 |
| 2 | V | S | L | S | T | A | W | I | I | 40.94 | 1.000 |
| 3 | V | S | L | S | M | A | W | I | I | 4.38 | 1.000 |
| 4 | M | S | L | S | T | A | * | T | I | 1.77 | 1.200 |
| 5 | V | S | Q | S | T | A | W | T | I | 1.00 | 1.000 |
| 6 | V | S | L | P | T | A | * | T | I | 0.46 | 1.200 |
| 7 | V | S | L | S | T | S | W | I | I | 0.31 | 1.000 |
| 8 | V | S | L | S | T | A | W | I | V | 0.08 | 1.000 |
| 9 | M | A | L | S | T | A | * | T | I | 0.08 | 1.200 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10X1.aApr07-unspliced | main_exon | 3UTR | chr1 | 158,578,919 | 158,578,922 | - |
| CDS | chr1 | 158,578,922 | 158,579,848 | - | ||
| 5UTR | chr1 | 158,579,848 | 158,579,899 | - | ||