OR1E1 Olfactory Receptor
| Gene Symbol | OR1E11 (View this gene in GeneCards) |
| Family | 1 |
| Subfamily | E |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | OR17-2, OR17-32, OR17-18, HSA12, OR17-4, HGMP07I, OR13-66, OR5-85, HsOR17.1.14, ORL255, ORL20 |
| External Ids | HGNC: 8189 GeneBank: AF087916, AF179761, AF399550, BK004237, BK004353, HSHGM071, HSU04642, HSU04682, NM_003553, U86222, U86274 ORDB: ORL255, ORL20 |
| Build #39 labels | OR1E1, OR1E9P, OR1E5, OR1E6 |
| Chromosomal location | 17:3,397,469-3,398,410 (-) |
| Cluster | 17@3b |
| Synteny | CLIC#39 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR1E2 | 92.26% | 323 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR1E1F | 81% | 303 |
| Mouse | Or1e1 | 84% | 314 |
| Mouse | Or1e1c | 84% | 311 |
| Mouse | Or1e1b-ps | 81% | 312 |
| Rat | Or1e1 | 84% | 314 |
| Rat | Or1e1c | 82% | 311 |
| Cow | OR1E1H | 83% | 314 |
| Cow | OR1E1G | 83% | 314 |
| Cow | OR1E1I | 82% | 314 |
| Orang | OR1E2P | 81% | 354 |
| Horse | OR1E1L | 84% | 309 |
| Horse | OR1E1K | 81% | 314 |
| Horse | OR1E1MP | 81% | 314 |
| Chimp | OR1E2 | 94% | 312 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | CO247872 |
| mRNA | BC166630 |
| GNF Atlas2 | 214515_at |
Sequence information
| Nucleotide sequence |
ATGATGGGACAAAATCAAACCAGCATCTCAGACTTCCTGCTCCTGGGCCTGCCCATCCAA CCAGAGCAGCAAAACCTGTGCTATGCCCTGTTCTTGGCCATGTATCTTACCACCCTCCTG GGGAACCTCCTCATCATTGTCCTCATTCGACTGGACTCCCATCTCCACACGCCTATGTAT TTGTTTCTCAGCAACTTGTCCTTCTCTGACCTCTGCTTCTCTTCCGTGACCATTCCCAAG TTGTTACAGAACATGCAGAACCAGGACCCATCCATCCCCTATGCGGACTGCCTGACCCAA ATGTACTTCTTCCTGTTATTTGGAGACCTGGAGAGCTTCCTCCTTGTGGCCATGGCCTAT GACCGCTATGTGGCCATCTGCTTCCCCCTGCACTACACCGCCATCATGAGCCCCATGCTC TGTCTCGCCCTGGTGGCGCTGTCCTGGGTGCTGACCACCTTCCATGCCATGTTACACACT TTACTCATGGCCAGGTTGTGTTTTTGTGCAGACAATGTGATCCCCCACTTTTTCTGTGAT ATGTCTGCTCTGCTGAAGCTGGCCTTCTCTGACACTCGAGTTAATGAATGGGTGATATTT ATCATGGGAGGGCTCATTCTTGTCATCCCATTCCTACTCATCCTTGGGTCCTATGCAAGA ATTGTCTCCTCCATCCTCAAGGTCCCTTCTTCTAAGGGTATCTGCAAGGCCTTCTCTACT TGTGGCTCCCACCTGTCTGTGGTGTCACTGTTCTATGGAACCGTTATTGGTCTCTACTTA TGCTCATCAGCTAATAGTTCTACTCTAAAGGACACTGTCATGGCTATGATGTACACTGTG GTGACCCCCATGCTGAACCCCTTCATCTACAGCCTGAGGAACAGAGACATGAAGGGAGCC CTGAGCAGAGTCATTCATCAGAAGAAAACTTTCTTCTCTCTC |
| Conceptual translation |
MMGQNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPMY LFLSNLSFSDLCFSSVTIPKLLQNMQNQDPSIPYADCLTQMYFFLLFGDLESFLLVAMAY DRYVAICFPLHYTAIMSPMLCLALVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCD MSALLKLAFSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSILKVPSSKGICKAFST CGSHLSVVSLFYGTVIGLYLCSSANSSTLKDTVMAMMYTVVTPMLNPFIYSLRNRDMKGA LSRVIHQKKTFFSL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 17 | 100 | -100 | SYN | A/T | G/G | 1000GP (YRI, YRI) |
| 17 | 3,300,921 | 3,300,921 | NS | G/A | P/S | rs379856 (DbSNP) |
| 17 | 3,300,934 | 3,300,934 | SYN | A/T | G/G | rs769422 (DbSNP) |
| 17 | 3,300,943 | 3,300,943 | SYN | A/G | T/T | rs58631068 (DbSNP) |
| 17 | 3,300,946 | 3,300,946 | SYN | T/C | G/G | rs404983 (DbSNP) |
| 17 | 3,300,970 | 3,300,970 | SYN | C/G | L/L | rs61735439 (DbSNP) |
| 17 | 3,301,246 | 3,301,246 | SYN | A/G | T/T | rs11078447 (DbSNP) |
| 17 | 3,301,275 | 3,301,275 | NS | C/G | V/L | rs1735010 (DbSNP) |
| 17 | 3,301,278 | 3,301,278 | NS | C/T | A/T | rs150989 (DbSNP) |
| 17 | 3,301,319 | 3,301,319 | NS | A/G | L/P | rs1735011 (DbSNP) |
| 17 | 3,301,363 | 3,301,363 | SYN | G/T | L/L | rs11078448 (DbSNP) |
| 17 | 3,301,480 | 3,301,480 | SYN | G/A | S/S | rs61735437 (DbSNP) |
| 17 | 3,301,534 | 3,301,534 | SYN | T/C | T/T | rs61735436 (DbSNP) |
| 17 | 3,301,549 | 3,301,549 | SYN | A/G | D/D | rs150988 (DbSNP) |
| 17 | 3,301,626 | 3,301,626 | NS | A/G | C/R | rs62091316 (DbSNP) |
| 17 | 3,397,640 | 3,397,640 | SYN | A/T | G/G | 1000GP (CEU, CHBJPT) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 42 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| V280L | A143T | A95V | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | V | A | A | 98.62 | 0.068 |
| 2 | V | T | A | 0.92 | 0.068 |
| 3 | V | A | V | 0.31 | 0.068 |
| 4 | L | A | A | 0.15 | 0.068 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR1E1.aApr07-unspliced | main_exon | 3UTR | chr17 | 3,397,104 | 3,397,469 | - |
| CDS | chr17 | 3,397,469 | 3,398,410 | - | ||