OR1E2 Olfactory Receptor
| Gene Symbol | OR1E21 (View this gene in GeneCards) |
| Family | 1 |
| Subfamily | E |
| Pseudogene | No |
| CORP pseudogene probability score | 0.14 (functional) |
| Aliases | OR17-136, OR17-135, OR17-93, OR17-17, OR17-19, OR17-3, HsOR17.1.16, ORL264, ORL738 |
| External Ids | HGNC: 8190 GeneBank: AF087925, AF399551, BK004235, BK004352, BK004585, HSU04686, NM_003554, U86241, U86242 ORDB: ORL264, ORL738 |
| Build #39 labels | OR1E2 |
| Chromosomal location | 17:3,432,873-3,433,841 (-) |
| Cluster | 17@3b |
| Synteny | CLIC#39 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR1E1 | 92.26% | 323 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR1E1 | 82% | 321 |
| Mouse | Or1e1c | 83% | 315 |
| Mouse | Or1e1 | 82% | 318 |
| Rat | Or1e1 | 82% | 318 |
| Rat | Or1e1c | 81% | 315 |
| Cow | OR1E1 | 80% | 323 |
| Cow | OR1E1H | 80% | 321 |
| Orang | OR1E2P | 81% | 365 |
| Horse | OR1E1 | 82% | 318 |
| Horse | OR1E1L | 81% | 318 |
| Chimp | OR1E1 | 93% | 321 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | CO249498 |
| mRNA | AB529302 |
| GNF Atlas2 | 208587_s_at |
Sequence information
| Nucleotide sequence |
ATGATGGGACAAAATCAAACCAGCATCTCAGACTTCCTGCTCCTGGGCCTGCCCATCCAA CCAGAGCAGCAAAACCTGTGCTATGCCCTGTTCTTGGCCATGTATCTTACCACCCTCCTG GGGAACCTCCTCATCATTGTCCTCATTCGACTGGACTCCCATCTCCACACGCCTGTGTAT TTGTTTCTCAGCAACTTGTCCTTCTCTGACCTCTGCTTTTCCTCAGTCACAATGCCCAAA TTGCTGCAGAACATGCAGAACCAAGACCCATCCATCCCCTATGCAGACTGCCTGACCCAA ATGTACTTCTTCTTGTATTTTTCGGATCTAGAGAGCTTCCTCCTTGTGGCCATGGCCTAT GACCGCTATGTGGCCATCTGCTTCCCCATGCACTACACCGCCATCTGCTTCCTCCTGCAC TACACCGCCATCATGAGCCCCATGCTCTGTCTCTCCGTGGTGGCGCTGTCCTGGGTGCTG ACCACCTTCCATGCCATGTTACACACTTTACTCATGGCCAGGTTGTGTTTTTGTGCAGAC AATGTGATCCCCCACTTTTTCTGTGATATGTCTGCTCTGCTGAAGCTGGCCTGCTCTGAC ACTCGAGTTAATGAATGGGTGATATTTATCATGGGAGGGCTCATTCTTGTCATCCCATTC CTACTCATCCTTGGGTCCTATGCAAGAATTGTCTCCTCCATCCTCAAGGTCCCTTCTTCT AAGGGTATCTGCAAGGCCTTCTCTACTTGTGGCTCCCACCTCTCTGTGGTGTCACTGTTC TATGGGACCGTTATTGGTCTCTACTTATGCCCATCAGCTAATAGTTCTACTCTAAAGGAC ACTGTCATGGCTATGATGTACACTGTGGTGACCCCTATGCTGACCCCCTTCATCTACAGC CTGAGGAACAGAGACATGAAGGGAGCCCTGGAAAGGGTCATTTGTAAAAGGAAAAATCCC TTCCTTCTA |
| Conceptual translation |
MMGQNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPVY LFLSNLSFSDLCFSSVTMPKLLQNMQNQDPSIPYADCLTQMYFFLYFSDLESFLLVAMAY DRYVAICFPMHYTAICFLLHYTAIMSPMLCLSVVALSWVLTTFHAMLHTLLMARLCFCAD NVIPHFFCDMSALLKLACSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSILKVPSS KGICKAFSTCGSHLSVVSLFYGTVIGLYLCPSANSSTLKDTVMAMMYTVVTPMLTPFIYS LRNRDMKGALERVICKRKNPFLL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 17 | 100 | -100 | NS | A/C | S/A | 1000GP (YRI, YRI, YRI, YRI) |
| 17 | 3,336,260 | 3,336,260 | SYN | G/A | P/P | rs61739591 (DbSNP) |
| 17 | 3,336,374 | 3,336,374 | SYN | C/G | L/L | rs436972 (DbSNP) |
| 17 | 3,336,723 | 3,336,723 | NS | A/G | L/P | rs73296096 (DbSNP) |
| 17 | 3,336,799 | 3,336,798 | Ins(1) | -/T | rs34073940 (DbSNP) | |
| 17 | 3,336,845 | 3,336,845 | SYN | G/A | C/C | rs2640077 (DbSNP) |
| 17 | 3,336,899 | 3,336,898 | Ins(1) | -/T | rs34838055 (DbSNP) | |
| 17 | 3,337,057 | 3,337,057 | NS | G/A | R/C | rs769431 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 139 (Hasin) | |||
| 17 | 3,334,167 | 3,337,235 | Deletion | #243 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| V153L | S152A | M145V | D109Y | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | V | S | M | D | 97.47 | 1.000 |
| 2 | L | A | M | D | 1.61 | 1.000 |
| 3 | V | S | M | Y | 0.61 | 1.000 |
| 4 | V | S | V | D | 0.31 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR1E2.aApr07-unspliced | main_exon | 3UTR | chr17 | 3,432,866 | 3,432,873 | - |
| CDS | chr17 | 3,432,873 | 3,433,841 | - | ||
| 5UTR | chr17 | 3,433,841 | 3,433,848 | - | ||