OR1F12 Olfactory Receptor
| Gene Symbol | OR1F121 (View this gene in GeneCards) |
| Family | 1 |
| Subfamily | F |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OR6-12, dJ313I6.5, hs6M1-35P, HsOR6.2.8, ORL3139 |
| External Ids | HGNC: 13964 GeneBank: AB065468, BK004273, NG_004691, XM_498061 ORDB: ORL3139 |
| Build #39 labels | OR1F12 |
| Chromosomal location | 6:28,073,316-28,074,236 (+) |
| Cluster | 6@28a |
| Synteny | CLIC#12 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR1F1 | 61.24% | 307 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR1F41P | 79% | 277 |
| Mouse | Or1f12 | 86% | 307 |
| Rat | Or1f12-ps | 82% | 307 |
| Cow | OR1F15P | 64% | 303 |
| Orang | OR1F1 | 61% | 303 |
| Horse | OR1F15 | 66% | 306 |
| Chimp | OR1F12P | 98% | 307 |
Sequence information
| Nucleotide sequence |
ATGGAAGGGAAAAATCAAACCAATATCTCTGAATTTCTCCTCCTGGGCTTCTCAAGTTGG CAACAACAGCAGGTGCTACTCTTTGCACTTTTCCTGTGTCTCTATTTAACAGGGCTGTTT GGAAACTTACTCATCTTGCTGGCCATTGGCTCGGATCACTGCCTTCACACACCCATGTAT TTCTTCCTTGCCAATCTGTCCTTGGTAGACCTCTGCCTTCCCTCAGCCACAGTCCCCAAG ATGCTACTGAACATCCAAACCCAAACCCAAACCATCTCCTATCCCGGCTGCCTGGCTCAG ATGTATTTCTGTATGATGTTTGCCAATATGGACAATTTTCTTCTCACAGTGATGGCATAT GACCGTTACGTGGCCATCTGTCACCCTTTACATTACTCCACCATTATGGCCCTGCGCCTC TGTGCCTCTCTGGTAGCTGCACCTTGGGTCATTGCCATTTTGAACCCTCTCTTGCACACT CTTATGATGGCCCATCTGCACTTCTGCTCTGATAATGTTATCCACCATTTCTTCTGTGAT ATCAACTCTCTCCTCCCTCTGTCCTGTTCCGACACCAGTCTTAATCAGTTGAGTGTTCTG GCTACGGTGGGGCTGATCTTTGTGGTACCTTCAGTGTGTATCCTGGTATCCTATATCCTC ATTGTTTCTGCTGTGATGAAAGTCCCTTCTGCCCAAGGAAAACTCAAGGCTTTCTCTACC TGTGGATCTCACCTTGCCTTGGTCATTCTTTTCTATGGAGCAATCACAGGGGTCTATATG AGCCCCTTATCCAATCACTCTACTGAAAAAGACTCAGCCGCATCAGTCATTTTTATGGTT GTAGCACCTGTGTTGAATCCATTCATTTACAGTTTAAGAAACAATGAACTGAAGGGGACT TTAAAAAAGACCCTAAGCCGA |
| Conceptual translation |
MEGKNQTNISEFLLLGFSSWQQQQVLLFALFLCLYLTGLFGNLLILLAIGSDHCLHTPMY FFLANLSLVDLCLPSATVPKMLLNIQTQTQTISYPGCLAQMYFCMMFANMDNFLLTVMAY DRYVAICHPLHYSTIMALRLCASLVAAPWVIAILNPLLHTLMMAHLHFCSDNVIHHFFCD INSLLPLSCSDTSLNQLSVLATVGLIFVVPSVCILVSYILIVSAVMKVPSAQGKLKAFST CGSHLALVILFYGAITGVYMSPLSNHSTEKDSAASVIFMVVAPVLNPFIYSLRNNELKGT LKKTLSR Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 6 | 28,041,996 | 28,041,996 | Del(1) | -/A | rs34495429 (DbSNP) | |
| 6 | 28,041,669 | 28,041,668 | Ins(2) | -/CC | rs67996847 (DbSNP) | |
| 6 | 28,041,670 | 28,041,669 | Ins(2) | -/CC | rs61630977 (DbSNP) | |
| 6 | 28,041,671 | 28,041,670 | Ins(2) | -/CC | rs72340643 (DbSNP) | |
| 6 | 28,041,668 | 28,041,667 | Ins(2) | -/CC | rs35106887 (DbSNP) | |
| 6 | 28,041,977 | 28,041,977 | NS | A/G | N/S | rs73396550 (DbSNP) |
| 6 | 28,041,857 | 28,041,857 | NS | A/T | N/I | rs203870 (DbSNP) |
| 6 | 28,042,014 | 28,042,014 | SYN | A/G | R/R | rs203871 (DbSNP) |
| 6 | 28,041,906 | 28,041,906 | SYN | C/T | D/D | rs9380048 (DbSNP) |
| 6 | 28,074,079 | 28,074,079 | NS | T/A | I/N | 1000GP (CEU, CHBJPT) |
| 6 | 28,074,199 | 28,074,199 | NS | A/G | N/S | 1000GP (CEU, CHBJPT) |
| 6 | 100 | -100 | SYN | G/A | Q/Q | 1000GP (YRI) |
| 6 | 100 | -100 | NS | T/A | I/N | 1000GP (YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| G96S | I255N | N295S | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | G | I | N | 66.51 | 0.098 |
| 2 | G | I | S | 24.35 | 0.098 |
| 3 | G | N | N | 9.06 | 0.098 |
| 4 | S | I | N | 0.08 | 0.098 |