OR1K1 Olfactory Receptor
| Gene Symbol | OR1K11 (View this gene in GeneCards) |
| Family | 1 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.69 (pseudogene) |
| Aliases | hg99, HsOR9.6.15, ORL3219 |
| External Ids | HGNC: 8212 GeneBank: AB065726, AF399622, NM_080859 ORDB: ORL3219 |
| Build #39 labels | OR1K1 |
| Chromosomal location | 9:122,800,123-122,801,070 (+) |
| Cluster | 9@125 |
| Synteny | CLIC#21 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR1F1 | 55.34% | 309 |
| OR1L4 | 55.41% | 305 |
| OR1L6 | 54.75% | 305 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR1L6 | 56% | 305 |
| Mouse | Or1af1 | 55% | 301 |
| Rat | Or1af1 | 54% | 305 |
| Cow | OR1L4 | 56% | 305 |
| Orang | OR1K1P | 91% | 315 |
| Orang | OR1K1BP | 90% | 315 |
| Horse | OR1F1 | 56% | 312 |
| Chimp | OR1K1P | 96% | 316 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | AW858627 |
| mRNA | AB529306 |
| GNF Atlas2 | gnf1h10669_at |
Sequence information
| Nucleotide sequence |
ATGGAGGCTGCCAATGAGTCTTCAGAGGGAATCTCATTCGTTTTATTGGGACTGACAACA AGTCCTGGACAGCAGCGGCCTCTCTTTGTGCTGTTCTTGCTCTTGTATGTGGCCAGCCTC CTGGGTAATGGACTCATTGTGGCTGCCATCCAGGCCAGTCCAGCCCTTCATGCACCCATG TACTTCCTGCTGGCCCACCTGTCCTTTGCTGACCTCTGCTTCGCCTCCGTCACTGTGCCC AAGATGTTGGCCAACTTGTTGGCCCATGACCACTCCATCTCGCTGGCTGGCTGCCTGACC CAAATGTACTTCTTCTTTGCCCTGGGGGTAACTGATAGCTGTCTTCTGGCGGCCATGGCC TATGACTGCTACGTGGCCATCCGGCACCCCCTCCCCTATGCCACGAGGATGTCCCGGGCC ATGTGCGCAGCCCTGGTGGGAATGGCATGGCTGGTGTCCCACGTCCACTCCCTCCTGTAT ATCCTGCTCATGGCTCGCTTGTCCTTCTGTGCTTCCCACCAAGTGCCCCACTTCTTCTGT GACCACCAGCCTCTCTTAAGGCTCTCGTGCTCTGACACCCACCACATCCAGCTGCTCATC TTCACCGAGGGCGCCGCAGTGGTGGTCACTCCCTTCCTGCTCATCCTCGCCTCCTATGGG GCCATCGCAGCTGCCGTGCTCCAGCTGCCCTCAGCCTCTGGGAGGCTCCGGGCTGTGTCC ACCTGTGGCTCCCACCTGGCTGTGGTGAGCCTCTTCTATGGGACAGTCATTGCAGTCTAC TTCCAGGCCACATCCCGACGCGAGGCAGAGTGGGGCCGTGTGGCCACTGTCATGTACACT GTAGTCACCCCCATGCTGAACCCCATCATCTACAGCCTCTGGAATCGCGATGTACAGGGG GCACTCCGAGCCCTTCTCATTGGGCGAAGGATCTCAGCTAGTGACTCC |
| Conceptual translation |
MEAANESSEGISFVLLGLTTSPGQQRPLFVLFLLLYVASLLGNGLIVAAIQASPALHAPM YFLLAHLSFADLCFASVTVPKMLANLLAHDHSISLAGCLTQMYFFFALGVTDSCLLAAMA YDCYVAIRHPLPYATRMSRAMCAALVGMAWLVSHVHSLLYILLMARLSFCASHQVPHFFC DHQPLLRLSCSDTHHIQLLIFTEGAAVVVTPFLLILASYGAIAAAVLQLPSASGRLRAVS TCGSHLAVVSLFYGTVIAVYFQATSRREAEWGRVATVMYTVVTPMLNPIIYSLWNRDVQG ALRALLIGRRISASDS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 9 | 100 | -100 | NS | G/A | R/Q | 1000GP (YRI, YRI) |
| 9 | 100 | -100 | SYN | T/C | G/G | 1000GP (YRI) |
| 9 | 122,800,248 | 122,800,248 | SYN | T/C | G/G | 1000GP (CEU, CHBJPT) |
| 9 | 122,800,372 | 122,800,372 | NS | G/A | A/T | 1000GP (CEU) |
| 9 | 122,800,924 | 122,800,924 | NS | G/A | E/K | 1000GP (CHBJPT) |
| 9 | 122,800,933 | 122,800,933 | NS | T/C | W/R | 1000GP (CHBJPT) |
| 9 | 125,562,527 | 125,562,527 | SYN | C/T | G/G | rs10985782 (DbSNP) |
| 9 | 125,562,651 | 125,562,651 | NS | A/G | T/A | rs55961642 (DbSNP) |
| 9 | 125,563,212 | 125,563,212 | NS | C/T | R/W | rs7046603 (DbSNP) |
| 9 | 125,563,347 | 125,563,347 | NS | G/T | A/S | rs56032401 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 79 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| A84T | A88S | M102V | R128Q | W271R | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | A | A | M | R | W | 91.17 | 0.734 |
| 2 | A | A | M | R | R | 6.91 | 0.734 |
| 3 | T | A | M | R | W | 1.31 | 0.734 |
| 4 | A | A | M | Q | W | 0.31 | 0.734 |
| 5 | A | A | V | R | W | 0.15 | 0.734 |
| 6 | T | A | M | Q | W | 0.08 | 0.734 |
| 7 | A | S | M | R | W | 0.08 | 0.734 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR1K1.aApr07-unspliced | main_exon | CDS | chr9 | 122,800,123 | 122,801,070 | + |
| 3UTR | chr9 | 122,801,070 | 122,801,073 | + | ||