OR1L3 Olfactory Receptor
| Gene Symbol | OR1L31 (View this gene in GeneCards) |
| Family | 1 |
| Subfamily | L |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | hRPK-465_F_21, OR9-28, OR9-D, HsOR9.6.11, ORL3218 |
| External Ids | HGNC: 8215 GeneBank: AB065492, BK004231, NM_001005234 ORDB: ORL3218 |
| Build #39 labels | OR1L3 |
| Chromosomal location | 9:122,675,130-122,676,101 (+) |
| Cluster | 9@125 |
| Synteny | CLIC#21 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR1L1 | 78.06% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR1L8 | 71% | 306 |
| Mouse | Or1l8 | 73% | 307 |
| Rat | Or1l8 | 73% | 307 |
| Cow | OR1L19 | 83% | 324 |
| Orang | OR1L12P | 94% | 321 |
| Horse | OR1L12 | 86% | 325 |
| Chimp | OR1L12P | 98% | 321 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136859 |
| GNF Atlas2 | gnf1h10671_at |
Sequence information
| Nucleotide sequence |
ATGGGAATGTCCAACCTGACAAGACTCTCTGAATTTATTCTCTTGGGACTCTCCTCTCGG TCTGAAGACCAGAGGCCACTCTTTGCCCTCTTTCTTATCATATACCTGGTCACTTTGATG GGAAATCTGCTCATCATCTTGGCTATCCACTCTGATCCTCGACTTCAAAACCCTATGTAT TTTTTCCTAAGCATCTTGTCCTTTGCTGATATTTGCTACACAACAGTCATAGTCCCAAAG ATGCTCGTGAACTTCTTATCAGAGAAAAAGACCATTTCCTATGCTGAATGTCTGGCACAG ATGTATTTCTTCCTGGTTTTTGGAAACATAGATAGTTATCTCCTGGCGGCTATGGCCATC AACCGCTGTGTAGCCATTTGTAACCCATTCCATTATGTCACTGTTATGAACCGCAGATGC TGTGTGTTGCTACTAGCATTCCCCATCACTTTCTCCTATTTCCACTCTCTCCTACATGTC CTCCTGGTGAATCGGCTCACCTTTTGTACATCAAATGTTATCCATCATTTTTTTTGTGAT GTCAACCCTGTGCTGAAACTGTCCTGCTCCTCCACCTTTGTCAATGAAATTGTGGCCATG ACAGAAGGGCTGGCCTCTGTGATGGCTCCATTTGTCTGTATCATCATCTCTTATCTAAGA ATTCTCATCGCTGTTCTCAAGATTCCCTCAGCAGCTGGAAAACACAAAGCCTTCTCCACC TGCAGCTCCCATCTCACTGTGGTGATTCTGTTTTATGGGAGTATTAGCTATGTCTATTTG CAGCCTTTGTCCAGCTATACTGTCAAGGACCGAATAGCAACAATCAACTACACTGTGTTG ACATCAGTGTTGAACCCATTTATCTACAGTTTAAGAAACAAAGACATGAAACGGGGCTTA CAGAAATTGATAAACAAGATTAAGTCTCAAATGAGTAGGTTCTCTACAAAGACCAATAAA ATCTGTGGACCC |
| Conceptual translation |
MGMSNLTRLSEFILLGLSSRSEDQRPLFALFLIIYLVTLMGNLLIILAIHSDPRLQNPMY FFLSILSFADICYTTVIVPKMLVNFLSEKKTISYAECLAQMYFFLVFGNIDSYLLAAMAI NRCVAICNPFHYVTVMNRRCCVLLLAFPITFSYFHSLLHVLLVNRLTFCTSNVIHHFFCD VNPVLKLSCSSTFVNEIVAMTEGLASVMAPFVCIIISYLRILIAVLKIPSAAGKHKAFST CSSHLTVVILFYGSISYVYLQPLSSYTVKDRIATINYTVLTSVLNPFIYSLRNKDMKRGL QKLINKIKSQMSRFSTKTNKICGP Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 9 | 125,437,411 | 125,437,410 | Ins(1) | -/G | rs35421332 (DbSNP) | |
| 9 | 125,437,482 | 125,437,482 | NS | A/G | K/R | rs61100236 (DbSNP) |
| 9 | 125,437,769 | 125,437,769 | NS | A/G | N/D | rs16912099 (DbSNP) |
| 9 | 125,437,568 | 125,437,568 | NS | C/G | R/G | rs12379744 (DbSNP) |
| 9 | 125,437,820 | 125,437,820 | NS | C/T | R/C | rs61480152 (DbSNP) |
| 9 | 125,437,725 | 125,437,725 | NS | C/T | A/V | rs16912096 (DbSNP) |
| 9 | 125,437,664 | 125,437,664 | NS | G/T | V/L | rs56304399 (DbSNP) |
| 9 | 125,438,077 | 125,438,077 | SYN | C/T | I/I | rs16912101 (DbSNP) |
| 9 | 122,675,477 | 122,675,477 | SYN | G/A | A/A | 1000GP (CEU) |
| 9 | 122,675,997 | 122,675,997 | NS | A/T | S/C | 1000GP (CEU) |
| 9 | 122,675,937 | 122,675,937 | NS | G/T | D/Y | 1000GP (CEU) |
| 9 | 122,675,272 | 122,675,272 | NS | C/T | A/V | 1000GP (CHBJPT) |
| 9 | 122,675,446 | 122,675,446 | NS | T/C | V/A | 1000GP (CHBJPT) |
| 9 | 122,675,490 | 122,675,490 | NS | A/G | N/D | 1000GP (CHBJPT) |
| 9 | 122,675,965 | 122,675,965 | NS | T/C | V/A | 1000GP (CHBJPT) |
| 9 | 122,676,099 | 122,676,099 | NS | C/T | P/S | 1000GP (CHBJPT) |
| 9 | 100 | -100 | NS | G/A | R/K | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 9 | 100 | -100 | SYN | T/C | Y/Y | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 9 | 125,435,804 | 125,440,267 | Inversion | Variation_59875 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R25K | R54Q | I65N | F68S | L86V | V106A | N121D | R138C | R165W | L204Q | V279A | T281I | P324S | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | R | R | I | F | L | V | N | R | R | L | V | T | P | 85.41 | 1.000 |
| 2 | R | R | I | F | L | A | D | R | R | L | A | T | S | 7.45 | 0.016 |
| 3 | R | R | I | F | L | V | D | R | R | L | V | T | P | 2.76 | 0.016 |
| 4 | K | R | I | F | L | V | D | C | R | L | V | T | P | 1.38 | 0.016 |
| 5 | R | R | I | F | L | A | D | R | R | L | V | T | P | 0.54 | 0.016 |
| 6 | R | R | I | F | V | V | N | R | R | L | V | T | P | 0.46 | 1.000 |
| 7 | K | R | I | F | L | V | D | R | R | Q | V | T | P | 0.38 | 0.016 |
| 8 | K | R | I | F | L | V | D | C | R | Q | V | T | P | 0.31 | 0.016 |
| 9 | R | R | I | S | L | V | N | R | R | L | V | T | P | 0.31 | 1.000 |
| 10 | R | R | I | F | L | A | D | R | R | L | V | T | S | 0.15 | 0.016 |
| 11 | R | R | I | F | L | V | N | R | W | L | V | T | P | 0.15 | 1.000 |
| 12 | R | R | N | F | L | V | N | R | R | L | V | T | P | 0.15 | 1.000 |
| 13 | R | R | I | F | L | V | D | C | R | L | V | T | P | 0.08 | 0.016 |
| 14 | R | R | I | F | L | V | D | R | W | L | A | T | P | 0.08 | 0.016 |
| 15 | R | R | I | F | L | A | N | R | R | L | A | T | S | 0.08 | 1.000 |
| 16 | R | R | I | F | L | V | D | R | R | L | A | T | S | 0.08 | 0.016 |
| 17 | R | R | I | F | L | A | N | R | R | L | A | T | P | 0.08 | 1.000 |
| 18 | R | Q | I | F | L | V | D | R | R | L | V | T | P | 0.08 | 0.016 |
| 19 | R | R | I | F | L | V | N | R | R | L | V | I | P | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR1L3.aApr07-unspliced | main_exon | CDS | chr9 | 122,675,130 | 122,676,101 | + |
| 3UTR | chr9 | 122,676,101 | 122,676,104 | + | ||