OR1L4 Olfactory Receptor
| Gene Symbol | OR1L41 (View this gene in GeneCards) |
| Family | 1 |
| Subfamily | L |
| Pseudogene | No |
| CORP pseudogene probability score | 0.02 (functional) |
| Aliases | hRPK-465_F_21, OST046, OR9-29, OR9-E, HsOR9.6.12, ORL3244 |
| External Ids | HGNC: 8216 GeneBank: AB065724, AF399562, BK004232, NM_001005235 ORDB: ORL3244 |
| Build #39 labels | OR1L4 |
| Chromosomal location | 9:122,723,990-122,724,922 (+) |
| Cluster | 9@125 |
| Synteny | CLIC#21 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR1L6 | 94.19% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR1L6 | 87% | 311 |
| Dog | OR1L6BP | 87% | 311 |
| Mouse | Or1l4b | 86% | 310 |
| Mouse | Or1l4 | 88% | 299 |
| Rat | Or1l4 | 86% | 311 |
| Rat | Or1l4b | 87% | 305 |
| Cow | OR1L6 | 85% | 311 |
| Cow | OR1L6C | 85% | 306 |
| Orang | OR1L6 | 93% | 310 |
| Orang | OR1L4P | 93% | 299 |
| Horse | OR1L6 | 89% | 311 |
| Horse | OR1L4C | 87% | 311 |
| Chimp | OR1L6 | 95% | 310 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | EG357665 |
| GNF Atlas2 | gnf1h10931_at |
Sequence information
| Nucleotide sequence |
ATGGAGACAAAGAATTATAGCAGCAGCACCTCAGGCTTCATCCTCCTGGGCCTCTCTTCC AACCCTAAGCTGCAGAAACCTCTCTTTGCCATCTTCCTCATCATGTACCTACTCACTGCG GTGGGGAATGTGCTCATCATCCTGGCCATCTACTCTGACCCCAGGCTCCACACCCCTATG TACTTTTTTCTCAGCAACTTGTCTTTCATGGATATCTGCTTCACAACAGTCATAGTGCCT AAGATGCTGGTGAATTTTCTATCAGAGACAAAGATTATCTCTTATGTGGGCTGCCTGATC CAGATGTACTTCTTCATGGCATTTGGGAACACTGACAGCTACCTGCTGGCCTCTATGGCC ATCGACCGGCTGGTGGCCATCTGCAACCCCTTACACTATGATGTGGTTATGAAACCATGG CATTGCCTACTCATGCTATTGGGTTCTTGCAGCATCTCCCACCTACATTCCCTGTTCCGC GTGCTACTTATGTCTCGCTTGTCTTTCTGTGCCTCTCACATCATTAAGCACTTTTTCTGT GACACCCAGCCTGTGCTAAAGCTCTCCTGCTCTGACACATCCTCCAGCCAGATGGTGGTG ATGACTGAGACCTTAGCTGTCATTGTGACCCCCTTCCTGTGTACCATCTTCTCCTACCTG CAAATCATCGTCACTGTGCTCAGAATCCCCTCTGCAGCCGGGAAGTGGAAGGCCTTCTCT ACCTGTGGCTCCCACCTCACTGTAGTGGTCCTGTTCTATGGGAGTGTCATCTATGTCTAT TTTAGGCCTCTGTCCATGTACTCAGTGATGAAGGGCCGGGTAGCCACAGTTATGTACACA GTAGTGACACCCATGCTGAACCCTTTCATCTACAGCCTGAGGAACAAAGATATGAAAAGG GGTTTGAAGAAATTAAGACACAGAATTTACTCA |
| Conceptual translation |
METKNYSSSTSGFILLGLSSNPKLQKPLFAIFLIMYLLTAVGNVLIILAIYSDPRLHTPM YFFLSNLSFMDICFTTVIVPKMLVNFLSETKIISYVGCLIQMYFFMAFGNTDSYLLASMA IDRLVAICNPLHYDVVMKPWHCLLMLLGSCSISHLHSLFRVLLMSRLSFCASHIIKHFFC DTQPVLKLSCSDTSSSQMVVMTETLAVIVTPFLCTIFSYLQIIVTVLRIPSAAGKWKAFS TCGSHLTVVVLFYGSVIYVYFRPLSMYSVMKGRVATVMYTVVTPMLNPFIYSLRNKDMKR GLKKLRHRIYS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 9 | 100 | -100 | NS | C/T | T/I | 1000GP (YRI, YRI) |
| 9 | 122,724,757 | 122,724,757 | SYN | C/T | V/V | 1000GP (CHBJPT) |
| 9 | 125,486,335 | 125,486,335 | NS | A/C | K/Q | rs58159408 (DbSNP) |
| 9 | 125,486,446 | 125,486,446 | NS | A/G | M/V | rs41316502 (DbSNP) |
| 9 | 125,486,968 | 125,486,968 | NS | A/G | R/G | rs2215530 (DbSNP) |
| 9 | 125,487,196 | 125,487,196 | NS | C/T | H/Y | rs12341025 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 9 | 125,486,953 | 125,514,075 | CopyNumber | Variation_100776 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T3I | P22S | K23Q | W140R | H141Y | Y310H | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | T | P | K | W | H | Y | 97.08 | 0.079 |
| 2 | T | P | K | R | H | Y | 1.38 | 0.079 |
| 3 | T | S | K | W | H | Y | 0.54 | 0.079 |
| 4 | T | P | K | W | H | H | 0.54 | 0.079 |
| 5 | T | P | Q | W | H | Y | 0.23 | 0.079 |
| 6 | T | P | K | W | Y | Y | 0.15 | 0.079 |
| 7 | I | P | K | W | H | Y | 0.08 | 0.079 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR1L4.aApr07-unspliced | main_exon | CDS | chr9 | 122,723,990 | 122,724,922 | + |
| 3UTR | chr9 | 122,724,922 | 122,724,925 | + | ||