OR1L6 Olfactory Receptor
| Gene Symbol | OR1L61 (View this gene in GeneCards) |
| Family | 1 |
| Subfamily | L |
| Pseudogene | No |
| CORP pseudogene probability score | 0.02 (functional) |
| Aliases | OR9-30, HShRPK-465_F_21, hg16, HsOR9.6.13, ORL3219 |
| External Ids | HGNC: 8218 GeneBank: AB065727, AF399563, BK004234, NM_001004453 ORDB: ORL3219 |
| Build #39 labels | OR1L6 |
| Chromosomal location | 9:122,749,848-122,750,780 (+) |
| Cluster | 9@125 |
| Synteny | CLIC#21 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR1L4 | 94.19% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR1L6BP | 87% | 310 |
| Mouse | Or1l4b | 86% | 307 |
| Mouse | Or1l4 | 88% | 298 |
| Rat | Or1l4 | 87% | 310 |
| Rat | Or1l4b | 87% | 304 |
| Cow | OR1L4 | 85% | 310 |
| Cow | OR1L6C | 84% | 307 |
| Orang | OR1L4P | 91% | 298 |
| Horse | OR1L6E | 86% | 310 |
| Horse | OR1L4C | 86% | 310 |
| Horse | OR1L4E | 85% | 310 |
| Chimp | OR1L4 | 95% | 310 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB529307 |
| GNF Atlas2 | gnf1h10670_at |
Sequence information
| Nucleotide sequence |
ATGGAGATAAAGAACTACAGCAGCAGCACCTCAGGCTTCATCCTCCTGGGCCTCTCTTCC AACCCTCAGCTGCAGAAACCTCTCTTTGCCATCTTCCTCATCATGTACCTGCTCGCTGCG GTGGGGAATGTGCTCATCATCCCGGCCATCTACTCTGACCCCAGGCTCCACACCCCTATG TACTTTTTTCTCAGCAACTTGTCTTTCATGGATATCTGCTTCACAACAGTCATAGTGCCT AAGATGCTGGTGAATTTTCTATCAGAGACAAAGGTTATCTCCTATGTGGGCTGCCTGGCC CAGATGTACTTCTTTATGGCATTTGGGAACACTGACAGCTACCTGCTGGCCTCTATGGCC ATCGACCGGCTGGTGGCCATCTGCAACCCCTTACACTATGATGTGGTTATGAAACCACGG CATTGCCTGCTCATGCTATTGGGTTCTTGCAGCATCTCCCACCTACATTCCCTGTTCCGC GTGCTACTTATGTCTCGCTTGTCTTTCTGTGCCTCTCACATCATTAAGCACTTTTTCTGT GACACCCAGCCTGTGCTAAAGCTCTCCTGCTCTGACACATCCTCCAGCCAGATGGTGGTG ATGACTGAGACCTTAGCTGTCATTGTGACCCCCTTCCTGTGTATCATCTTCTCCTACCTG CGAATCATGGTCACTGTGCTCAGAATCCCCTCTGCAGCCGGGAAGTGGAAGGCCTTCTCT ACCTGTGGCTCCCACCTCACTGCAGTAGCCCTTTTCTATGGGAGTATTATTTATGTCTAT TTTAGGCCCCTGTCCATGTACTCAGTGGTTAGGGACCGGGTAGCCACAGTTATGTACACA GTAGTGACACCCATGCTGAACCCTTTCATCTACAGCCTGAGGAACAAAGATATGAAGAGG GGTTTGAAGAAATTACAGGACAGAATTTACCGG |
| Conceptual translation |
MEIKNYSSSTSGFILLGLSSNPQLQKPLFAIFLIMYLLAAVGNVLIIPAIYSDPRLHTPM YFFLSNLSFMDICFTTVIVPKMLVNFLSETKVISYVGCLAQMYFFMAFGNTDSYLLASMA IDRLVAICNPLHYDVVMKPRHCLLMLLGSCSISHLHSLFRVLLMSRLSFCASHIIKHFFC DTQPVLKLSCSDTSSSQMVVMTETLAVIVTPFLCIIFSYLRIMVTVLRIPSAAGKWKAFS TCGSHLTAVALFYGSIIYVYFRPLSMYSVVRDRVATVMYTVVTPMLNPFIYSLRNKDMKR GLKKLQDRIYR Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 9 | 100 | -100 | NS | C/T | A/V | 1000GP (YRI, YRI, YRI, YRI) |
| 9 | 122,749,914 | 122,749,914 | NS | C/A | Q/K | 1000GP (CEU) |
| 9 | 122,750,159 | 122,750,159 | NS | C/G | F/L | 1000GP (CEU) |
| 9 | 122,750,491 | 122,750,491 | NS | T/C | I/T | 1000GP (CEU) |
| 9 | 122,750,509 | 122,750,509 | NS | G/A | R/Q | 1000GP (CEU) |
| 9 | 122,750,516 | 122,750,516 | NS | G/C | M/I | 1000GP (CEU) |
| 9 | 122,750,664 | 122,750,664 | NS | C/T | R/W | 1000GP (CEU) |
| 9 | 125,512,193 | 125,512,193 | NS | A/C | K/Q | rs10760252 (DbSNP) |
| 9 | 125,512,245 | 125,512,245 | NS | C/T | A/V | rs73571194 (DbSNP) |
| 9 | 125,512,408 | 125,512,408 | SYN | C/T | S/S | rs41309328 (DbSNP) |
| 9 | 125,512,575 | 125,512,575 | NS | A/G | Y/C | rs4838012 (DbSNP) |
| 9 | 125,512,770 | 125,512,770 | NS | C/T | T/I | rs10985760 (DbSNP) |
| 9 | 125,512,795 | 125,512,795 | NS | C/G | I/M | rs10818741 (DbSNP) |
| 9 | 125,512,826 | 125,512,826 | NS | A/G | R/G | rs28670025 (DbSNP) |
| 9 | 125,512,855 | 125,512,855 | SYN | C/T | G/G | rs10985761 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 9 | 125,486,953 | 125,514,075 | CopyNumber | Variation_100776 (DGV) |
| 9 | 125,512,027 | 125,515,059 | CopyNumber | #49 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| Q23K | A40V | M102T | F104L | C150Y | I215T | R221Q | M223I | G234R | R273W | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | K | A | M | F | Y | T | Q | I | R | R | 82.64 | 0.065 |
| 2 | Q | A | M | F | C | I | R | M | G | R | 6.22 | 0.079 |
| 3 | K | A | M | F | Y | I | R | M | R | R | 2.46 | 0.065 |
| 4 | K | A | M | F | Y | T | R | M | R | R | 2.00 | 0.065 |
| 5 | K | V | M | F | Y | T | Q | I | R | R | 1.69 | 0.065 |
| 6 | Q | A | M | L | C | I | R | M | G | R | 1.46 | 0.079 |
| 7 | K | A | M | F | C | I | R | M | G | R | 0.92 | 0.079 |
| 8 | K | A | M | F | Y | T | Q | I | R | W | 0.54 | 0.065 |
| 9 | K | A | M | F | Y | T | R | I | R | R | 0.46 | 0.065 |
| 10 | K | V | M | F | Y | I | R | M | R | R | 0.38 | 0.065 |
| 11 | K | A | M | F | Y | I | R | I | R | R | 0.23 | 0.065 |
| 12 | K | A | M | F | Y | I | Q | I | R | R | 0.15 | 0.065 |
| 13 | Q | A | M | F | Y | I | R | M | G | R | 0.15 | 0.079 |
| 14 | Q | A | M | F | Y | T | Q | I | R | R | 0.08 | 0.065 |
| 15 | Q | A | M | L | Y | I | R | M | G | R | 0.08 | 0.079 |
| 16 | K | A | M | F | Y | T | Q | I | G | R | 0.08 | 0.079 |
| 17 | K | A | M | L | C | I | R | M | G | R | 0.08 | 0.079 |
| 18 | K | V | M | F | Y | T | R | M | R | R | 0.08 | 0.065 |
| 19 | Q | A | M | F | C | I | R | M | G | W | 0.08 | 0.079 |
| 20 | Q | A | M | L | C | T | R | I | R | R | 0.08 | 0.065 |
| 21 | K | A | T | F | Y | T | Q | I | R | R | 0.08 | 0.065 |
| 22 | K | A | M | F | Y | I | R | M | G | R | 0.08 | 0.079 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR1L6.aApr07-unspliced | main_exon | 5UTR | chr9 | 122,749,740 | 122,749,848 | + |
| CDS | chr9 | 122,749,848 | 122,750,780 | + | ||
| 3UTR | chr9 | 122,750,780 | 122,750,783 | + | ||