OR1N2 Olfactory Receptor
| Gene Symbol | OR1N21 (View this gene in GeneCards) |
| Family | 1 |
| Subfamily | N |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OR9-23, HsOR9.6.5, ORL3246 |
| External Ids | HGNC: 15111 GeneBank: AB065720, AF399536, BK004445, NM_001004457 ORDB: ORL3246 |
| Build #39 labels | OR1N2 |
| Chromosomal location | 9:122,553,212-122,554,159 (+) |
| Cluster | 9@125 |
| Synteny | CLIC#21 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR1E1 | 56.82% | 308 |
| OR1F1 | 56.49% | 308 |
| OR1N1 | 60.13% | 301 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR1D6 | 60% | 303 |
| Mouse | Or1n2 | 88% | 316 |
| Rat | Or1n2 | 87% | 316 |
| Cow | OR1F1 | 59% | 311 |
| Orang | OR1N17P | 62% | 302 |
| Horse | OR1N2B | 88% | 316 |
| Chimp | OR1N1 | 60% | 301 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB529310 |
| GNF Atlas2 | gnf1h10673_at |
Sequence information
| Nucleotide sequence |
ATGGGAAAACCAGGCAGAGTGAACCAAACCACTGTTTCAGACTTCCTCCTTCTAGGACTC TCTGAGTGGCCAGAGGAGCAGCCTCTTCTGTTTGGCATCTTCCTTGGCATGTACCTGGTC ACCATGGTGGGGAACCTGCTCATTATCCTGGCCATCAGCTCTGACCCACACCTCCATACT CCCATGTACTTCTTTCTGGCCAACCTGTCATTAACTGATGCCTGTTTCACTTCTGCCTCC ATCCCCAAAATGCTGGCCAACATTCATACCCAGAGTCAGATCATCTCGTATTCTGGGTGT CTTGCACAGCTATATTTCCTCCTTATGTTTGGTGGCCTTGACAACTGCCTGCTGGCTGTG ATGGCATATGACCGCTATGTGGCCATCTGCCAACCACTCCATTACAGCACATCTATGAGT CCCCAGCTCTGTGCACTAATGCTGGGTGTGTGCTGGGTGCTAACCAACTGTCCTGCCCTG ATGCACACACTGTTGCTGACCCGCGTGGCTTTCTGTGCCCAGAAAGCCATCCCTCATTTC TATTGTGATCCTAGTGCTCTCCTGAAGCTTGCCTGCTCAGATACCCATGTAAACGAGCTG ATGATCATCACCATGGGCTTGCTGTTCCTCACTGTTCCCCTCCTGCTGATCGTCTTCTCC TATGTCCGCATTTTCTGGGCTGTGTTTGTCATCTCATCTCCTGGAGGGAGATGGAAGGCC TTCTCTACCTGTGGTTCTCATCTCACGGTGGTTCTGCTCTTCTATGGGTCTCTTATGGGT GTGTATTTACTTCCTCCATCAACTTACTCTACAGAGAGGGAAAGTAGGGCTGCTGTTCTC TATATGGTGATTATTCCCACGCTAAACCCATTCATTTATAGCTTGAGGAACAGAGACATG AAGGAGGCTTTGGGTAAACTTTTTGTCAGTGGAAAAACATTCTTTTTA |
| Conceptual translation |
MGKPGRVNQTTVSDFLLLGLSEWPEEQPLLFGIFLGMYLVTMVGNLLIILAISSDPHLHT PMYFFLANLSLTDACFTSASIPKMLANIHTQSQIISYSGCLAQLYFLLMFGGLDNCLLAV MAYDRYVAICQPLHYSTSMSPQLCALMLGVCWVLTNCPALMHTLLLTRVAFCAQKAIPHF YCDPSALLKLACSDTHVNELMIITMGLLFLTVPLLLIVFSYVRIFWAVFVISSPGGRWKA FSTCGSHLTVVLLFYGSLMGVYLLPPSTYSTERESRAAVLYMVIIPTLNPFIYSLRNRDM KEALGKLFVSGKTFFL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 9 | 125,316,218 | 125,316,217 | Ins(1) | -/G | rs35880826 (DbSNP) | |
| 9 | 125,316,350 | 125,316,350 | NS | C/T | T/M | rs1411272 (DbSNP) |
| 9 | 125,316,157 | 125,316,157 | NS | C/T | R/C | rs41316976 (DbSNP) |
| 9 | 125,315,557 | 125,315,557 | NS | C/T | R/W | rs1831370 (DbSNP) |
| 9 | 125,316,028 | 125,316,028 | NS | C/T | L/F | rs41297203 (DbSNP) |
| 9 | 125,316,179 | 125,316,179 | NS | G/T | G/V | rs1341044 (DbSNP) |
| 9 | 125,316,240 | 125,316,240 | SYN | A/G | V/V | rs71511510 (DbSNP) |
| 9 | 125,315,778 | 125,315,778 | SYN | C/G | S/S | rs1411271 (DbSNP) |
| 9 | 125,315,542 | 125,315,542 | SYN | C/T | L/L | rs1831369 (DbSNP) |
| 9 | 125,316,042 | 125,316,042 | SYN | C/T | P/P | rs1341043 (DbSNP) |
| 9 | 125,316,033 | 125,316,033 | SYN | C/T | Y/Y | rs1341042 (DbSNP) |
| 9 | 122,553,878 | 122,553,878 | NS | C/T | R/C | 1000GP (CEU, CHBJPT) |
| 9 | 122,553,900 | 122,553,900 | NS | T/G | V/G | 1000GP (CEU) |
| 9 | 122,553,749 | 122,553,749 | NS | T/C | F/L | 1000GP (CEU) |
| 9 | 122,553,263 | 122,553,263 | SYN | C/T | L/L | 1000GP (CEU, CHBJPT) |
| 9 | 122,554,071 | 122,554,071 | NS | C/T | T/M | 1000GP (CEU, CHBJPT) |
| 9 | 122,553,763 | 122,553,763 | SYN | T/C | P/P | 1000GP (CEU, CHBJPT) |
| 9 | 122,553,278 | 122,553,278 | NS | T/C | W/R | 1000GP (CEU, CHBJPT) |
| 9 | 122,553,499 | 122,553,499 | SYN | G/C | S/S | 1000GP (CEU, CHBJPT) |
| 9 | 122,553,961 | 122,553,961 | SYN | G/A | V/V | 1000GP (CEU) |
| 9 | 122,553,754 | 122,553,754 | SYN | T/C | Y/Y | 1000GP (CEU, CHBJPT) |
| 9 | 100 | -100 | SYN | C/T | L/L | 1000GP (YRI, YRI, YRI, YRI) |
| 9 | 100 | -100 | NS | T/C | W/R | 1000GP (YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 9 | 125,313,731 | 125,319,766 | CopyNumber | Variation_70789 (DGV) |
| 9 | 125,315,391 | 125,318,438 | CopyNumber | #48 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| W37R | R139C | F194L | R237C | V244G | T301M | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | R | R | F | R | G | M | 51.84 | 0.371 |
| 2 | W | R | F | R | V | T | 17.97 | 0.371 |
| 3 | W | R | F | C | G | T | 11.29 | 0.327 |
| 4 | W | R | F | R | G | T | 7.53 | 0.371 |
| 5 | W | R | L | R | G | T | 5.84 | 0.371 |
| 6 | W | R | F | R | G | M | 3.69 | 0.371 |
| 7 | R | C | F | R | G | M | 1.15 | 0.371 |
| 8 | R | R | F | R | G | T | 0.23 | 0.371 |
| 9 | R | R | F | R | V | M | 0.15 | 0.371 |
| 10 | W | C | F | R | G | T | 0.15 | 0.371 |
| 11 | R | R | L | R | G | T | 0.08 | 0.371 |
| 12 | W | R | L | R | V | T | 0.08 | 0.371 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR1N2.aApr07-unspliced | main_exon | 5UTR | chr9 | 122,553,170 | 122,553,212 | + |
| CDS | chr9 | 122,553,212 | 122,554,159 | + | ||
| 3UTR | chr9 | 122,554,159 | 122,554,162 | + | ||