OR2AG2 Olfactory Receptor
| Gene Symbol | OR2AG21 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | AG |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OR11-76, HsOR11.4.1 |
| External Ids | HGNC: 15143 GeneBank: AB065539, AF399487, BK004747, NM_001004490 |
| Build #39 labels | OR2AG2P |
| Chromosomal location | 11:6,768,010-6,768,957 (-) |
| Cluster | 11@7 |
| Synteny | CLIC#24 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2AG1 | 87.03% | 316 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2AG1 | 82% | 315 |
| Dog | OR2AG1C | 81% | 315 |
| Dog | OR2AG2C | 81% | 315 |
| Mouse | Or2ag2 | 82% | 316 |
| Mouse | Or2ag2b | 80% | 316 |
| Rat | Or2ag2 | 80% | 316 |
| Cow | OR2AG1 | 82% | 314 |
| Cow | OR2AG1E | 81% | 310 |
| Orang | OR2AG1P | 84% | 254 |
| Horse | OR2AG2C | 81% | 316 |
| Horse | OR2AG1 | 81% | 316 |
| Chimp | OR2AG1 | 87% | 316 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | EG357714 |
| mRNA | BC140734 |
Sequence information
| Nucleotide sequence |
ATGGAGCTCCGGAACTCCACCTTGGGAAGCGGCTTCATCTTGGTGGGGATTCTGAATGAC AGTGGGTCTCCTGAACTGCTCTATGCTACATTTACAATCCTATACATGTTGGCACTGACC AGCAATGGTCTGCTGCTCCTGGCCATCACCATAGAAGCCCGGCTCCACATGCCCATGTAC CTCCTGCTTGGGCAGCTCTCTCTCATGGACCTCCTGTTCACATCTGTTGTCACTCCCAAG GCCCTTGCGGACTTTCTGCGCAGAGAAAACACTATCTCCTTTGGAGGCTGTGCACTTCAG ATGTTCCTGGCACTGACAATGGGTAGCGCTGAGGACCTCCTACTGGCCTTCATGGCCTAT GACAGGTATGTGGCCATTTGTCATCCTCTGAAATACATGACCCTCATGAGCCCAAGAGTC TGCTGGATCATGGTGGCCACATCCTGGATCCTGGCATCCCTGATTGCTATAGGACATACC ATGTACACTATGCACCTCCCTTTCTGTGTGTCCTGGGAAATCAGGCATCTGCTCTGTGAG ATCCCACCCTTGCTGAAGTTGGCCTGTGCTGATACCTCCAGGTATGAGCTTATAATATAC GTGACAGGTGTGACTTTCCTCTTGCTCCCCATTTCTGCCATTGTGGCCTCCTACACACTA GTCCTATTCACTGTGCTTCGTATGCCATCAAATGAGGGGAGGAAGAAAGCCCTTGTCACC TGCTCTTCCCACCTGATTGTGGTCGGGATGTTCTATGGAGCTGCCACATTCATGTATGTC TTGCCCAGTTCCTTCCACAGCCCCAAACAAGACAACATCATCTCTGTTTTCTACACAATT GTCACTCCAGCCCTGAATCCACTCATCTACAGCCTGAGGAATAAGGAGGTCATGCGGGCC TTGAGGAGGGTCCTGGGAAAATACATACTGCTGGCACATTCCACGCTC |
| Conceptual translation |
MELRNSTLGSGFILVGILNDSGSPELLYATFTILYMLALTSNGLLLLAITIEARLHMPMY LLLGQLSLMDLLFTSVVTPKALADFLRRENTISFGGCALQMFLALTMGSAEDLLLAFMAY DRYVAICHPLKYMTLMSPRVCWIMVATSWILASLIAIGHTMYTMHLPFCVSWEIRHLLCE IPPLLKLACADTSRYELIIYVTGVTFLLLPISAIVASYTLVLFTVLRMPSNEGRKKALVT CSSHLIVVGMFYGAATFMYVLPSSFHSPKQDNIISVFYTIVTPALNPLIYSLRNKEVMRA LRRVLGKYILLAHSTL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 6,789,251 | 6,789,250 | Ins(1) | -/A | rs35806826 (DbSNP) | |
| 11 | 6,789,929 | 6,789,929 | NS | A/C | L/R | rs11828782 (DbSNP) |
| 11 | 6,790,028 | 6,790,028 | NS | C/G | R/P | rs10839616 (DbSNP) |
| 11 | 6,789,294 | 6,789,294 | NS | C/G | G/R | rs7924459 (DbSNP) |
| 11 | 6,790,106 | 6,790,106 | NS | C/T | C/Y | rs7102536 (DbSNP) |
| 11 | 6,768,875 | 6,768,875 | NS | T/C | Y/C | 1000GP (CEU, CHBJPT) |
| 11 | 6,768,797 | 6,768,797 | NS | C/G | R/P | 1000GP (CEU, CHBJPT) |
| 11 | 6,768,013 | 6,768,013 | SYN | C/T | T/T | 1000GP (CHBJPT) |
| 11 | 6,768,698 | 6,768,698 | NS | C/A | R/L | 1000GP (CHBJPT) |
| 11 | 100 | -100 | SYN | T/C | G/G | 1000GP (YRI, YRI) |
| 11 | 100 | -100 | NS | C/A | R/L | 1000GP (YRI, YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R299G | R87L | R54P | Y28C | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | R | R | R | C | 31.95 | 0.118 |
| 2 | R | L | R | C | 23.12 | 0.118 |
| 3 | G | R | P | C | 15.98 | 0.118 |
| 4 | R | R | R | Y | 13.21 | 0.118 |
| 5 | R | R | P | C | 9.68 | 0.118 |
| 6 | G | R | R | C | 5.61 | 0.118 |
| 7 | G | L | R | C | 0.31 | 0.118 |
| 8 | R | L | P | C | 0.08 | 0.118 |
| 9 | R | L | R | Y | 0.08 | 0.118 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2AG2.aApr07-unspliced | main_exon | 3UTR | chr11 | 6,767,856 | 6,768,010 | - |
| CDS | chr11 | 6,768,010 | 6,768,957 | - | ||