OR2AP1 Olfactory Receptor
| Gene Symbol | OR2AP11 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | AP |
| Pseudogene | No |
| CORP pseudogene probability score | 0.08 (functional) |
| Aliases | OR12-9, HsOR12.5.24 |
| External Ids | HGNC: 15335 GeneBank: AB065868, BK004260, NG_004283 |
| Build #39 labels | OR2AP1P |
| Chromosomal location | 12:55,574,415-55,575,341 (+) |
| Cluster | 12@56 |
| Synteny | CLIC#31 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6C4 | 80.26% | 309 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|
Expression evidences
| Source | Accession |
|---|---|
| ESTs | BG186556 |
| GNF Atlas2 | gnf1h01630_s_at |
| GNF Atlas2 | gnf1h10896_at |
Sequence information
| Nucleotide sequence |
ATGAAAAATAAAACCGTGTTAACTGAGTTTATCCTTCTGGGTCTAACAGATGTCCCTGAA CTCCAGGTGGCAGTTTTCACCTTTCTTTTCCTTGCGTATTTACTCAGCATCCTTGGAAAT CTGACTATCCTCATCCTCACCTTGCTGGACTCCCACCTTCAGACTCCCATGTATTTCTTT CTCCGGAACTTCTCCTTCTTGGAAATTTCCTTCACAAACATCTTCATTCCAAGGGTCCTG ATTAGCATCACAACAGGGAACAAGAGTATCAGCTTTGCTGGCTGCTTCACTCAGTATTTC TTTGCCATGTTCCTTGGGGCTACAGAGTTTTACCTTCTGGCTGCCATGTCCTATGACCGC TATGTGGCCATCTGCAAACCTCTGCATTACACCACCATCATGAGCAGCAGAATCTGCATC CAGCTGATTTTCTGCTCTTGGCTGGGTGGGCTAATGGCTATTATACCAACAATCACCCTG ATGAGTCAGCAGGACTTTTGTGCATCCAACAGACTGAATCATTACTTCTGTGACTATGAG CCTCTTCTGGAACTCTCATGTTCAGACACAAGCCTCATAGAGAAGGTTGTCTTTCTTGTG GCATCTGTGACCCTGGTGGTCACTCTGGTGCTAGTGATTCTCTCCTATGCATTCATTATC AAGACTATTCTGAAGCTCCCCTCTGCCCAACAAAGGACAAAAGCCTTTTCCACATGTTCT TCCCACATGATTGTCATCTCCCTCTCTTACGGAAGCTGCATGTTTATGTACATTAATCCC TCTGCAAAAGAAGGGGATACATTCAACAAGGGAGTAGCTCTACTCATTACTTCAGTTGCT CCTTTGTTGAACCCCTTTATTTACACCCTAAGGAACCAACAGGTAAAACAACCCTTCAAG GATATGGTCAAAAAGCTTCTGAATCTT |
| Conceptual translation |
MKNKTVLTEFILLGLTDVPELQVAVFTFLFLAYLLSILGNLTILILTLLDSHLQTPMYFF LRNFSFLEISFTNIFIPRVLISITTGNKSISFAGCFTQYFFAMFLGATEFYLLAAMSYDR YVAICKPLHYTTIMSSRICIQLIFCSWLGGLMAIIPTITLMSQQDFCASNRLNHYFCDYE PLLELSCSDTSLIEKVVFLVASVTLVVTLVLVILSYAFIIKTILKLPSAQQRTKAFSTCS SHMIVISLSYGSCMFMYINPSAKEGDTFNKGVALLITSVAPLLNPFIYTLRNQQVKQPFK DMVKKLLNL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 12 | 55,968,949 | 55,968,949 | NS | A/G | R/G | rs61746285 (DbSNP) |
| 12 | 55,968,322 | 55,968,322 | NS | A/T | T/S | rs62623428 (DbSNP) |
| 12 | 55,968,498 | 55,968,498 | NS | C/A | F/L | rs1896038 (DbSNP) |
| 12 | 55,968,676 | 55,968,676 | NS | C/G | L/V | rs56012703 (DbSNP) |
| 12 | 55,968,994 | 55,968,994 | NS | C/G | H/D | rs17117692 (DbSNP) |
| 12 | 55,969,028 | 55,969,028 | NS | C/T | T/I | rs17117696 (DbSNP) |
| 12 | 55,968,284 | 55,968,284 | NS | C/T | P/L | rs62624967 (DbSNP) |
| 12 | 55,968,813 | 55,968,813 | SYN | G/T | L/L | rs11171571 (DbSNP) |
| 12 | 55,574,500 | 55,574,500 | NS | T/C | L/P | 1000GP (CEU) |
| 12 | 55,575,165 | 55,575,165 | NS | G/A | G/R | 1000GP (CEU, CHBJPT) |
| 12 | 55,575,149 | 55,575,149 | SYN | C/A | V/V | 1000GP (CHBJPT) |
| 12 | 100 | -100 | NS | T/C | L/P | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
| 12 | 100 | -100 | SYN | G/A | K/K | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 12 | 55,832,210 | 56,001,052 | CopyNumber | Variation_4780 (DGV) |
| CopyNumber | 206 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| L29P | L67S | R137K | L160V | S247F | G251R | D266H | T277I | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | L | L | R | L | S | G | D | T | 89.48 | 0.244 |
| 2 | L | L | R | L | S | R | D | T | 5.45 | 0.244 |
| 3 | L | L | R | L | S | G | H | I | 1.77 | 0.244 |
| 4 | P | L | R | L | S | R | D | T | 1.69 | 0.270 |
| 5 | L | L | R | V | S | G | D | T | 1.23 | 0.244 |
| 6 | L | S | R | L | S | G | D | T | 0.15 | 0.244 |
| 7 | L | L | R | V | F | G | D | T | 0.08 | 0.244 |
| 8 | L | L | K | L | S | G | D | T | 0.08 | 0.244 |
| 9 | L | L | R | L | S | G | D | I | 0.08 | 0.244 |