OR2C3 Olfactory Receptor
| Gene Symbol | OR2C31 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | C |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | OR1-30, OR1-29, HsOR1.5.3 |
| External Ids | HGNC: 15005 GeneBank: AB065649, AF399495, BK004471, BK004609 |
| Build #39 labels | OR2C3, OR2C5P |
| Chromosomal location | 1:247,531,552-247,532,511 (-) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2B7P | 60% | 305 |
| OR2G3 | 58.36% | 305 |
| OR2W6P | 58.03% | 305 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2B7 | 61% | 304 |
| Mouse | Or2w6 | 61% | 306 |
| Rat | Or2w6 | 61% | 305 |
| Cow | OR2C3B | 85% | 310 |
| Orang | OR2G6 | 59% | 315 |
| Horse | OR2C3D | 84% | 319 |
| Horse | OR2C3C | 83% | 320 |
| Chimp | OR2G6P | 59% | 305 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | EL735234 |
| mRNA | CU689001 |
| GNF Atlas2 | gnf1h03760_at |
Sequence information
| Nucleotide sequence |
ATGATGGAAATAGCCAATGTGAGTTCTCCAGAAGTCTTTGTCCTCCTGGGCTTCTCCACA CGACCCTCACTAGAAACTGTCCTCTTCATAGTTGTCTTGAGTTTTTACATGGTATCGATC TTGGGCAATGGCATCATCATTCTGGTCTCCCATACAGATGTGCACCTCCACACACCTATG TACTTCTTTCTTGCCAACCTCCCCTTCCTGGACATGAGCTTCACCACGAGCATTGTCCCA CAGCTCCTGGCTAACCTCTGGGGACCACAGAAAACCATAAGCTATGGAGGGTGTGTGGTC CAGTTCTATATCTCCCATTGGCTGGGGGCAACCGAGTGTGTCCTGCTGGCCACCATGTCC TATGACCGCTACGCTGCCATCTGCAGGCCACTCCATTACACTGTCATTATGCATCCACAG CTTTGCCTTGGGCTAGCTTTGGCCTCCTGGCTGGGGGGTCTGACCACCAGCATGGTGGGC TCCACGCTCACCATGCTCCTACCGCTGTGTGGGAACAATTGCATCGACCACTTCTTTTGC GAGATGCCCCTCATTATGCAACTGGCTTGTGTGGATACCAGCCTCAATGAGATGGAGATG TACCTGGCCAGCTTTGTCTTTGTTGTCCTGCCTCTGGGGCTCATCCTGGTCTCTTACGGC CACATTGCCCGGGCCGTGTTGAAGATCAGGTCAGCAGAAGGGCGGAGAAAGGCATTCAAC ACCTGTTCTTCCCACGTGGCTGTGGTGTCTCTGTTTTACGGGAGCATCATCTTCATGTAT CTCCAGCCAGCCAAGAGCACCTCCCATGAGCAGGGCAAGTTCATAGCTCTGTTCTACACC GTAGTCACTCCTGCGCTGAACCCACTTATTTACACCCTGAGGAACACGGAGGTGAAGAGC GCCCTCCGGCACATGGTATTAGAGAACTGCTGTGGCTCTGCAGGCAAGCTGGCGCAAATT |
| Conceptual translation |
MMEIANVSSPEVFVLLGFSTRPSLETVLFIVVLSFYMVSILGNGIIILVSHTDVHLHTPM YFFLANLPFLDMSFTTSIVPQLLANLWGPQKTISYGGCVVQFYISHWLGATECVLLATMS YDRYAAICRPLHYTVIMHPQLCLGLALASWLGGLTTSMVGSTLTMLLPLCGNNCIDHFFC EMPLIMQLACVDTSLNEMEMYLASFVFVVLPLGLILVSYGHIARAVLKIRSAEGRRKAFN TCSSHVAVVSLFYGSIIFMYLQPAKSTSHEQGKFIALFYTVVTPALNPLIYTLRNTEVKS ALRHMVLENCCGSAGKLAQI Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | G/C | L/V | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | G/A | L/L | 1000GP (YRI) |
| 1 | 247,531,647 | 247,531,647 | NS | G/C | L/V | 1000GP (CEU, CHBJPT) |
| 1 | 247,531,656 | 247,531,656 | SYN | G/A | L/L | 1000GP (CEU, CHBJPT) |
| 1 | 247,532,125 | 247,532,125 | NS | C/G | R/S | 1000GP (CEU) |
| 1 | 247,532,310 | 247,532,310 | NS | G/A | P/S | 1000GP (CEU, CHBJPT) |
| 1 | 247,532,454 | 247,532,454 | NS | T/C | T/A | 1000GP (CEU, CHBJPT) |
| 1 | 247,694,949 | 247,694,949 | NS | C/G | V/L | rs6702693 (DbSNP) |
| 1 | 247,694,958 | 247,694,958 | SYN | A/G | L/L | rs6702695 (DbSNP) |
| 1 | 247,695,283 | 247,695,283 | NS | C/G | Q/H | rs58515573 (DbSNP) |
| 1 | 247,695,427 | 247,695,427 | NS | C/G | R/S | rs34220133 (DbSNP) |
| 1 | 247,695,612 | 247,695,612 | NS | A/G | S/P | rs6657127 (DbSNP) |
| 1 | 247,695,631 | 247,695,631 | Del(1) | -/G | rs71570435 (DbSNP) | |
| 1 | 247,695,756 | 247,695,756 | NS | C/T | A/T | rs6697472 (DbSNP) |
| 1 | 247,695,757 | 247,695,757 | SYN | G/A | S/S | rs61746303 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 247,074,430 | 248,328,835 | CopyNumber | Variation_6816 (DGV) |
| 1 | 247,692,854 | 247,695,913 | Deletion | #182 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| L288V | H176Q | R128S | P67S | S38L | I29L | T19A | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | L | H | R | S | S | I | A | 75.73 | 0.954 |
| 2 | V | H | R | S | S | I | A | 12.44 | 0.954 |
| 3 | L | H | S | S | S | I | A | 7.37 | 0.954 |
| 4 | L | H | R | S | S | I | T | 2.38 | 0.954 |
| 5 | L | Q | R | S | S | I | A | 1.54 | 0.954 |
| 6 | L | H | R | P | S | I | T | 0.23 | 0.954 |
| 7 | L | H | R | S | L | I | A | 0.23 | 0.954 |
| 8 | L | H | R | S | S | L | A | 0.08 | 0.954 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2C3.aApr07 | main_exon | 3UTR | chr1 | 247,530,133 | 247,531,552 | - |
| CDS | chr1 | 247,531,552 | 247,532,511 | - | ||
| 5UTR | chr1 | 247,532,511 | 247,532,540 | - | ||
| exon_5UTR | chr1 | 247,533,507 | 247,533,840 | - | ||