OR2C3 Olfactory Receptor
Gene Symbol | OR2C31 (View this gene in GeneCards) |
Family | 2 |
Subfamily | C |
Pseudogene | No |
CORP pseudogene probability score | |
Aliases | OR1-30, OR1-29, HsOR1.5.3 |
External Ids | HGNC: 15005 GeneBank: AB065649, AF399495, BK004471, BK004609 |
Build #39 labels | OR2C3, OR2C5P |
Chromosomal location | 1:247,531,552-247,532,511 (-) |
Cluster | 1@248 |
Synteny | CLIC#5 |
Remarks |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR2B7P | 60% | 305 |
OR2G3 | 58.36% | 305 |
OR2W6P | 58.03% | 305 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR2B7 | 61% | 304 |
Mouse | Or2w6 | 61% | 306 |
Rat | Or2w6 | 61% | 305 |
Cow | OR2C3B | 85% | 310 |
Orang | OR2G6 | 59% | 315 |
Horse | OR2C3D | 84% | 319 |
Horse | OR2C3C | 83% | 320 |
Chimp | OR2G6P | 59% | 305 |
Expression evidences
Source | Accession |
---|---|
ESTs | EL735234 |
mRNA | CU689001 |
GNF Atlas2 | gnf1h03760_at |
Sequence information
Nucleotide sequence |
ATGATGGAAATAGCCAATGTGAGTTCTCCAGAAGTCTTTGTCCTCCTGGGCTTCTCCACA CGACCCTCACTAGAAACTGTCCTCTTCATAGTTGTCTTGAGTTTTTACATGGTATCGATC TTGGGCAATGGCATCATCATTCTGGTCTCCCATACAGATGTGCACCTCCACACACCTATG TACTTCTTTCTTGCCAACCTCCCCTTCCTGGACATGAGCTTCACCACGAGCATTGTCCCA CAGCTCCTGGCTAACCTCTGGGGACCACAGAAAACCATAAGCTATGGAGGGTGTGTGGTC CAGTTCTATATCTCCCATTGGCTGGGGGCAACCGAGTGTGTCCTGCTGGCCACCATGTCC TATGACCGCTACGCTGCCATCTGCAGGCCACTCCATTACACTGTCATTATGCATCCACAG CTTTGCCTTGGGCTAGCTTTGGCCTCCTGGCTGGGGGGTCTGACCACCAGCATGGTGGGC TCCACGCTCACCATGCTCCTACCGCTGTGTGGGAACAATTGCATCGACCACTTCTTTTGC GAGATGCCCCTCATTATGCAACTGGCTTGTGTGGATACCAGCCTCAATGAGATGGAGATG TACCTGGCCAGCTTTGTCTTTGTTGTCCTGCCTCTGGGGCTCATCCTGGTCTCTTACGGC CACATTGCCCGGGCCGTGTTGAAGATCAGGTCAGCAGAAGGGCGGAGAAAGGCATTCAAC ACCTGTTCTTCCCACGTGGCTGTGGTGTCTCTGTTTTACGGGAGCATCATCTTCATGTAT CTCCAGCCAGCCAAGAGCACCTCCCATGAGCAGGGCAAGTTCATAGCTCTGTTCTACACC GTAGTCACTCCTGCGCTGAACCCACTTATTTACACCCTGAGGAACACGGAGGTGAAGAGC GCCCTCCGGCACATGGTATTAGAGAACTGCTGTGGCTCTGCAGGCAAGCTGGCGCAAATT |
Conceptual translation |
MMEIANVSSPEVFVLLGFSTRPSLETVLFIVVLSFYMVSILGNGIIILVSHTDVHLHTPM YFFLANLPFLDMSFTTSIVPQLLANLWGPQKTISYGGCVVQFYISHWLGATECVLLATMS YDRYAAICRPLHYTVIMHPQLCLGLALASWLGGLTTSMVGSTLTMLLPLCGNNCIDHFFC EMPLIMQLACVDTSLNEMEMYLASFVFVVLPLGLILVSYGHIARAVLKIRSAEGRRKAFN TCSSHVAVVSLFYGSIIFMYLQPAKSTSHEQGKFIALFYTVVTPALNPLIYTLRNTEVKS ALRHMVLENCCGSAGKLAQI Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
1 | 100 | -100 | NS | G/C | L/V | 1000GP (YRI, YRI, YRI, YRI, YRI) |
1 | 100 | -100 | SYN | G/A | L/L | 1000GP (YRI) |
1 | 247,531,647 | 247,531,647 | NS | G/C | L/V | 1000GP (CEU, CHBJPT) |
1 | 247,531,656 | 247,531,656 | SYN | G/A | L/L | 1000GP (CEU, CHBJPT) |
1 | 247,532,125 | 247,532,125 | NS | C/G | R/S | 1000GP (CEU) |
1 | 247,532,310 | 247,532,310 | NS | G/A | P/S | 1000GP (CEU, CHBJPT) |
1 | 247,532,454 | 247,532,454 | NS | T/C | T/A | 1000GP (CEU, CHBJPT) |
1 | 247,694,949 | 247,694,949 | NS | C/G | V/L | rs6702693 (DbSNP) |
1 | 247,694,958 | 247,694,958 | SYN | A/G | L/L | rs6702695 (DbSNP) |
1 | 247,695,283 | 247,695,283 | NS | C/G | Q/H | rs58515573 (DbSNP) |
1 | 247,695,427 | 247,695,427 | NS | C/G | R/S | rs34220133 (DbSNP) |
1 | 247,695,612 | 247,695,612 | NS | A/G | S/P | rs6657127 (DbSNP) |
1 | 247,695,631 | 247,695,631 | Del(1) | -/G | rs71570435 (DbSNP) | |
1 | 247,695,756 | 247,695,756 | NS | C/T | A/T | rs6697472 (DbSNP) |
1 | 247,695,757 | 247,695,757 | SYN | G/A | S/S | rs61746303 (DbSNP) |
Variations - CNVs
Chr | Start | End | Type | Sources |
---|---|---|---|---|
1 | 247,074,430 | 248,328,835 | CopyNumber | Variation_6816 (DGV) |
1 | 247,692,854 | 247,695,913 | Deletion | #182 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
L288V | H176Q | R128S | P67S | S38L | I29L | T19A | % Freq | CORP | |
---|---|---|---|---|---|---|---|---|---|
1 | L | H | R | S | S | I | A | 75.73 | 0.954 |
2 | V | H | R | S | S | I | A | 12.44 | 0.954 |
3 | L | H | S | S | S | I | A | 7.37 | 0.954 |
4 | L | H | R | S | S | I | T | 2.38 | 0.954 |
5 | L | Q | R | S | S | I | A | 1.54 | 0.954 |
6 | L | H | R | P | S | I | T | 0.23 | 0.954 |
7 | L | H | R | S | L | I | A | 0.23 | 0.954 |
8 | L | H | R | S | S | L | A | 0.08 | 0.954 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR2C3.aApr07 | main_exon | 3UTR | chr1 | 247,530,133 | 247,531,552 | - |
CDS | chr1 | 247,531,552 | 247,532,511 | - | ||
5UTR | chr1 | 247,532,511 | 247,532,540 | - | ||
exon_5UTR | chr1 | 247,533,507 | 247,533,840 | - |