OR2D3 Olfactory Receptor
| Gene Symbol | OR2D31 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | D |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OR11-89, HsOR11.4.8, ORL3430 |
| External Ids | HGNC: 15146 GeneBank: AB065825, AF399592, BK004294, NM_001004684 ORDB: ORL3430 |
| Build #39 labels | OR2D3 |
| Chromosomal location | 11:6,921,050-6,921,991 (+) |
| Cluster | 11@7 |
| Synteny | CLIC#24 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2D2 | 63.84% | 307 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2D3D | 89% | 314 |
| Mouse | Or2d3 | 84% | 304 |
| Mouse | Or2d3b | 83% | 307 |
| Mouse | Or2d3c | 82% | 307 |
| Rat | Or2d3 | 83% | 307 |
| Rat | Or2d36 | 80% | 314 |
| Cow | OR2D3G | 82% | 307 |
| Orang | OR2D3P | 94% | 314 |
| Horse | OR2D3I | 81% | 307 |
| Chimp | OR2F1D | 56% | 304 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | BX495865 |
| mRNA | BC137209 |
| GNF Atlas2 | gnf1h11112_at |
Sequence information
| Nucleotide sequence |
ATGGGAGAAGAAAACCAAACCTTTGTGTCCAAGTTTATCTTCCTGGGTCTTTCACAGGAC TTGCAGACCCAGATCCTGCTATTTATCCTTTTCCTCATCATTTATCTGCTGACCGTGCTT GGAAACCAGCTCATCATCATTCTCATCTTCCTGGATTCTCGCCTTCACACTCCCATGTAT TTTTTTCTTAGAAATCTCTCCTTTGCAGATCTCTGTTTCTCTACTAGCATTGTCCCTCAA GTGTTGGTTCACTTCTTGGTAAAGAGGAAAACCATTTCTTTTTATGGGTGTATGACACAG ATAATTGTCTTTCTTCTGGTTGGGTGTACAGAGTGTGCGCTGCTGGCAGTGATGTCCTAT GACCGGTATGTGGCTGTCTGCAAGCCCCTGTACTACTCTACCATCATGACACAACGGGTG TGTCTCTGGCTGTCCTTCAGGTCCTGGGCCAGTGGGGCACTAGTGTCTTTAGTAGATACC AGCTTTACTTTCCATCTTCCCTACTGGGGACAGAATATAATCAATCACTACTTTTGTGAA CCTCCTGCCCTCCTGAAGCTGGCTTCCATAGACACTTACAGCACAGAAATGGCCATCTTT TCAATGGGCGTGGTAATCCTCCTGGCCCCTGTCTCCCTGATTCTTGGTTCTTATTGGAAT ATTATCTCCACTGTTATCCAGATGCAGTCTGGGGAAGGGAGACTCAAGGCTTTTTCCACC TGTGGCTCCCATCTTATTGTTGTTGTCCTCTTCTATGGGTCAGGAATATTCACCTACATG CGACCAAACTCCAAGACTACAAAAGAACTGGATAAAATGATATCTGTGTTCTATACAGCG GTGACTCCAATGTTGAACCCCATAATTTATAGCTTGAGGAACAAAGATGTCAAAGGGGCT CTCAGGAAACTAGTTGGGAGAAAGTGCTTCTCTCATAGGCAG |
| Conceptual translation |
MGEENQTFVSKFIFLGLSQDLQTQILLFILFLIIYLLTVLGNQLIIILIFLDSRLHTPMY FFLRNLSFADLCFSTSIVPQVLVHFLVKRKTISFYGCMTQIIVFLLVGCTECALLAVMSY DRYVAVCKPLYYSTIMTQRVCLWLSFRSWASGALVSLVDTSFTFHLPYWGQNIINHYFCE PPALLKLASIDTYSTEMAIFSMGVVILLAPVSLILGSYWNIISTVIQMQSGEGRLKAFST CGSHLIVVVLFYGSGIFTYMRPNSKTTKELDKMISVFYTAVTPMLNPIIYSLRNKDVKGA LRKLVGRKCFSHRQ Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | C/A | L/I | 1000GP (YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | C/T | V/V | 1000GP (YRI, YRI, YRI, YRI) |
| 11 | 6,921,245 | 6,921,245 | NS | C/A | L/I | 1000GP (CEU, CHBJPT) |
| 11 | 6,921,286 | 6,921,286 | SYN | T/C | P/P | 1000GP (CEU) |
| 11 | 6,921,358 | 6,921,358 | SYN | C/T | V/V | 1000GP (CEU) |
| 11 | 6,921,388 | 6,921,388 | SYN | G/A | A/A | 1000GP (CEU) |
| 11 | 6,921,397 | 6,921,397 | SYN | A/C | A/A | 1000GP (CEU, CHBJPT) |
| 11 | 6,921,464 | 6,921,464 | NS | C/T | R/W | 1000GP (CEU, CHBJPT) |
| 11 | 6,921,495 | 6,921,495 | NS | G/C | W/S | 1000GP (CEU, CHBJPT) |
| 11 | 6,921,684 | 6,921,684 | NS | C/T | S/F | 1000GP (CEU) |
| 11 | 6,921,721 | 6,921,721 | SYN | T/C | T/T | 1000GP (CEU, CHBJPT) |
| 11 | 6,942,476 | 6,942,476 | NS | A/C | I/L | rs10839658 (DbSNP) |
| 11 | 6,942,589 | 6,942,589 | Del(1) | -/C | rs59264610 (DbSNP) | |
| 11 | 6,942,628 | 6,942,628 | SYN | A/C | A/A | rs11605995 (DbSNP) |
| 11 | 6,942,695 | 6,942,695 | NS | C/T | R/W | rs12806437 (DbSNP) |
| 11 | 6,942,726 | 6,942,726 | NS | C/G | S/W | rs10839659 (DbSNP) |
| 11 | 6,942,952 | 6,942,952 | SYN | T/C | T/T | rs2035844 (DbSNP) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T73A | L82I | I108T | R155W | S164F | W165S | L200F | S228F | M300V | A316V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | T | L | I | R | S | W | L | S | M | A | 35.48 | 0.141 |
| 2 | T | I | I | R | S | S | L | S | M | A | 28.88 | 0.141 |
| 3 | T | I | I | R | S | W | L | S | M | A | 18.13 | 0.141 |
| 4 | T | L | I | W | S | W | L | S | M | A | 12.60 | 0.141 |
| 5 | T | L | I | R | F | W | L | S | M | A | 2.46 | 0.141 |
| 6 | T | L | I | R | F | W | L | S | M | V | 0.92 | 0.141 |
| 7 | T | I | I | R | S | W | F | S | M | A | 0.38 | 0.141 |
| 8 | T | L | I | R | S | W | L | S | V | A | 0.38 | 0.141 |
| 9 | T | L | I | R | S | S | L | S | M | A | 0.23 | 0.141 |
| 10 | T | L | T | W | S | W | L | S | M | A | 0.23 | 0.141 |
| 11 | T | I | I | R | S | S | L | F | M | A | 0.15 | 0.141 |
| 12 | A | L | I | R | S | W | L | S | M | A | 0.08 | 0.141 |
| 13 | T | L | I | W | S | S | L | S | M | A | 0.08 | 0.141 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2D3.aApr07-unspliced | main_exon | 5UTR | chr11 | 6,921,002 | 6,921,050 | + |
| CDS | chr11 | 6,921,050 | 6,921,991 | + | ||
| 3UTR | chr11 | 6,921,991 | 6,921,994 | + | ||